Memory and Optogenetic Intervention: Separating the Engram from the Ecphory. Robins, S. K. Philosophy of Science. Paper doi abstract bibtex Optogenetics makes possible the control of neural activity with light. In this paper, I explore how the development of this experimental tool has brought about methodological and theoretical advances in the neurobiological study of memory. I begin with Semon's (1921) distinction between the engram and the ecphory, explaining how these concepts present a methodological challenge to investigating memory. Optogenetics provides a way to intervene into the engram without the ecphory that, in turn, opens up new means for testing theories of memory error. I focus on a series of experiments where optogenetics is used to study false memory and forgetting. Abstract Optogenetics makes possible the control of neural activity with light. In this paper, I explore how the development of this experimental tool has brought about methodological and theoretical advances in the neurobiological study of memory. I begin with Semon's (1921) distinction between the engram and the ecphory, explaining how these concepts present a methodological challenge to investigating memory. Optogenetics provides a way to intervene into the engram without the ecphory that, in turn, opens up new means for testing theories of memory error. I focus on a series of experiments where optogenetics is used to study false memory and forgetting.
@article{Robinsa,
abstract = {Optogenetics makes possible the control of neural activity with light. In this paper, I explore how the development of this experimental tool has brought about methodological and theoretical advances in the neurobiological study of memory. I begin with Semon's (1921) distinction between the engram and the ecphory, explaining how these concepts present a methodological challenge to investigating memory. Optogenetics provides a way to intervene into the engram without the ecphory that, in turn, opens up new means for testing theories of memory error. I focus on a series of experiments where optogenetics is used to study false memory and forgetting. Abstract Optogenetics makes possible the control of neural activity with light. In this paper, I explore how the development of this experimental tool has brought about methodological and theoretical advances in the neurobiological study of memory. I begin with Semon's (1921) distinction between the engram and the ecphory, explaining how these concepts present a methodological challenge to investigating memory. Optogenetics provides a way to intervene into the engram without the ecphory that, in turn, opens up new means for testing theories of memory error. I focus on a series of experiments where optogenetics is used to study false memory and forgetting.},
author = {Robins, Sarah K.},
doi = {10.1086/699692},
file = {:Users/khm/Library/Application Support/Mendeley Desktop/Downloaded/Robins - 2018 - Memory and Optogenetic Intervention Separating the Engram from the Ecphory.pdf:pdf},
journal = {Philosophy of Science},
title = {{Memory and Optogenetic Intervention: Separating the Engram from the Ecphory}},
url = {http://www.journals.uchicago.edu/t-and-c}
}
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