@Article{RSM:Rod2002,
  author =       "D.M. Roden and J.R. Balser and J.r. George AL and M.E.
                 Anderson",
  title =        "Cardiac ion channels.",
  journal =      "Annu Rev Physiol",
  year =         "2002",
  volume =       "64",
  pages =        "431--475",
  robnote =      "The normal electrophysiologic behavior of the heart is
                 determined by ordered propagation of excitatory stimuli
                 that result in rapid depolarization and slow
                 repolarization, thereby generating action potentials in
                 individual myocytes. Abnormalities of impulse
                 generation, propagation, or the duration and
                 configuration of individual cardiac action potentials
                 form the basis of disorders of cardiac rhythm, a
                 continuing major public health problem for which
                 available drugs are incompletetly effective and often
                 dangerous. The integrated activity of specific ionic
                 currents generates action potentials, and the genes
                 whose expression results in the molecular components
                 underlying individual ion currents in heart have been
                 cloned. This review discusses these new tools and how
                 their application to the problem of arrhythmias is
                 generating new mechanistic insights to identify
                 patients at risk for this condition and developing
                 improved antiarrhythmic therapies.",
  bibdate =      "Mon Nov 20 07:50:06 2006",
}

{"_id":"TZKC8FnwfboE84KdX","bibbaseid":"roden-balser-al-anderson-cardiacionchannels-2002","downloads":0,"creationDate":"2016-07-01T21:38:39.941Z","title":"Cardiac ion channels.","author_short":["Roden, D.","Balser, J.","AL, J. G.","Anderson, M."],"year":2002,"bibtype":"article","biburl":"http://www.sci.utah.edu/~macleod/Bibtex/biglit.bib","bibdata":{"bibtype":"article","type":"article","author":[{"firstnames":["D.M."],"propositions":[],"lastnames":["Roden"],"suffixes":[]},{"firstnames":["J.R."],"propositions":[],"lastnames":["Balser"],"suffixes":[]},{"firstnames":["J.r.","George"],"propositions":[],"lastnames":["AL"],"suffixes":[]},{"firstnames":["M.E."],"propositions":[],"lastnames":["Anderson"],"suffixes":[]}],"title":"Cardiac ion channels.","journal":"Annu Rev Physiol","year":"2002","volume":"64","pages":"431–475","robnote":"The normal electrophysiologic behavior of the heart is determined by ordered propagation of excitatory stimuli that result in rapid depolarization and slow repolarization, thereby generating action potentials in individual myocytes. Abnormalities of impulse generation, propagation, or the duration and configuration of individual cardiac action potentials form the basis of disorders of cardiac rhythm, a continuing major public health problem for which available drugs are incompletetly effective and often dangerous. The integrated activity of specific ionic currents generates action potentials, and the genes whose expression results in the molecular components underlying individual ion currents in heart have been cloned. This review discusses these new tools and how their application to the problem of arrhythmias is generating new mechanistic insights to identify patients at risk for this condition and developing improved antiarrhythmic therapies.","bibdate":"Mon Nov 20 07:50:06 2006","bibtex":"@Article{RSM:Rod2002,\n author = \"D.M. Roden and J.R. Balser and J.r. George AL and M.E.\n Anderson\",\n title = \"Cardiac ion channels.\",\n journal = \"Annu Rev Physiol\",\n year = \"2002\",\n volume = \"64\",\n pages = \"431--475\",\n robnote = \"The normal electrophysiologic behavior of the heart is\n determined by ordered propagation of excitatory stimuli\n that result in rapid depolarization and slow\n repolarization, thereby generating action potentials in\n individual myocytes. Abnormalities of impulse\n generation, propagation, or the duration and\n configuration of individual cardiac action potentials\n form the basis of disorders of cardiac rhythm, a\n continuing major public health problem for which\n available drugs are incompletetly effective and often\n dangerous. The integrated activity of specific ionic\n currents generates action potentials, and the genes\n whose expression results in the molecular components\n underlying individual ion currents in heart have been\n cloned. This review discusses these new tools and how\n their application to the problem of arrhythmias is\n generating new mechanistic insights to identify\n patients at risk for this condition and developing\n improved antiarrhythmic therapies.\",\n bibdate = \"Mon Nov 20 07:50:06 2006\",\n}\n\n","author_short":["Roden, D.","Balser, J.","AL, J. G.","Anderson, M."],"key":"RSM:Rod2002","id":"RSM:Rod2002","bibbaseid":"roden-balser-al-anderson-cardiacionchannels-2002","role":"author","urls":{},"metadata":{"authorlinks":{}},"downloads":0,"html":""},"search_terms":["cardiac","ion","channels","roden","balser","al","anderson"],"keywords":[],"authorIDs":[],"dataSources":["5HG3Kp8zRwDd7FotB"]}