Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Roemer, F. W., Zhang, Y., Niu, J., Lynch, J. A., Crema, M. D., Marra, M. D., Nevitt, M. C., Felson, D. T., Hughes, L. B., El-Khoury, G. Y., Englund, M., & Guermazi, A. 252(3):772--780. doi abstract bibtex PURPOSE: To assess baseline factors that may predict fast tibiofemoral cartilage loss over a 30-month period. MATERIALS AND METHODS: The Multicenter Osteoarthritis (MOST) study is a longitudinal study of individuals who have or who are at high risk for knee osteoarthritis. The HIPAA-compliant protocol was approved by the institutional review boards of all participating centers, and written informed consent was obtained from all participants. Magnetic resonance (MR) images were read according to the Whole-Organ Magnetic Resonance Imaging Score (WORMS) system. Only knees with minimal baseline cartilage damage (WORMS \textless or = 2.5) were included. Fast cartilage loss was defined as a WORMS of at least 5 (large full-thickness loss, less than 75% of the subregion) in any subregion at
@article{roemer_tibiofemoral_2009,
title = {Tibiofemoral joint osteoarthritis: risk factors for {MR}-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study.},
volume = {252},
issn = {1527-1315 0033-8419},
doi = {10.1148/radiol.2523082197},
abstract = {{PURPOSE}: To assess baseline factors that may predict fast tibiofemoral cartilage loss over a 30-month period. {MATERIALS} {AND} {METHODS}: The Multicenter Osteoarthritis ({MOST}) study is a longitudinal study of individuals who have or who are at high risk for knee osteoarthritis. The {HIPAA}-compliant protocol was approved by the institutional review boards of all participating centers, and written informed consent was obtained from all participants. Magnetic resonance ({MR}) images were read according to the Whole-Organ Magnetic Resonance Imaging Score ({WORMS}) system. Only knees with minimal baseline cartilage damage ({WORMS} {\textless} or = 2.5) were included. Fast cartilage loss was defined as a {WORMS} of at least 5 (large full-thickness loss, less than 75\% of the subregion) in any subregion at},
pages = {772--780},
number = {3},
journaltitle = {Radiology},
shortjournal = {Radiology},
author = {Roemer, Frank W. and Zhang, Yuqing and Niu, Jingbo and Lynch, John A. and Crema, Michel D. and Marra, Monica D. and Nevitt, Michael C. and Felson, David T. and Hughes, Laura B. and El-Khoury, George Y. and Englund, Martin and Guermazi, Ali},
date = {2009-09},
pmid = {19635831},
pmcid = {PMC2734891},
keywords = {Aged, Cartilage, Articular/*pathology, Female, Femur/pathology, Humans, Image Interpretation, Computer-Assisted/methods, Logistic Models, Longitudinal Studies, Magnetic Resonance Imaging/*methods, Male, Middle Aged, Osteoarthritis, Knee/*pathology, Risk Factors, Tibia/pathology, United States/epidemiology}
}
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