DNA methylation in Trypanosoma cruzi. Rojas, M. V. & Galanti, N. FEBS letters, 263(1):113–116, April, 1990. doi abstract bibtex DNA isolated from the protozoan Trypanosoma cruzi has been found to contain 5-methylcytosine. Analysis of T. cruzi DNA by both HpaII and MspI restriction endonucleases suggests that the sequence -CCGG- is not methylated. Probably T. cruzi DNA also contains N6-methyladenine. This report constitutes the first clear demonstration of the presence of methylated bases in the nuclear DNA from trypanosomes.
@article{rojas_dna_1990,
title = {{DNA} methylation in {Trypanosoma} cruzi},
volume = {263},
issn = {0014-5793},
doi = {10.1016/0014-5793(90)80717-w},
abstract = {DNA isolated from the protozoan Trypanosoma cruzi has been found to contain 5-methylcytosine. Analysis of T. cruzi DNA by both HpaII and MspI restriction endonucleases suggests that the sequence -CCGG- is not methylated. Probably T. cruzi DNA also contains N6-methyladenine. This report constitutes the first clear demonstration of the presence of methylated bases in the nuclear DNA from trypanosomes.},
language = {eng},
number = {1},
journal = {FEBS letters},
author = {Rojas, M. V. and Galanti, N.},
month = apr,
year = {1990},
pmid = {2185032},
keywords = {Adenine, Animals, DNA, Hydrolysis, Methionine, Methylation, Molecular Weight, Purine Nucleotides, Pyrimidine Nucleotides, Trypanosoma cruzi},
pages = {113--116},
}
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