@article{rojas_novel_2019,
	title = {Novel {Organ}-{Specific} {Genetic} {Factors} for {Quantitative} {Resistance} to {Late} {Blight} in {Potato}},
	copyright = {© 2019, Posted by Cold Spring Harbor Laboratory. This pre-print is available under a Creative Commons License (Attribution 4.0 International), CC BY 4.0, as described at http://creativecommons.org/licenses/by/4.0/},
	url = {https://www.biorxiv.org/content/biorxiv/early/2019/03/04/567289.full.pdf},
	doi = {10.1101/567289},
	abstract = {{\textless}h3{\textgreater}Abstract{\textless}/h3{\textgreater} {\textless}p{\textgreater}Potato, \textit{Solanum tuberosum}, is one of the highest consumed food in the world, being the basis of the diet of millions of people. The main limiting and destructive disease of potato is late blight, caused by \textit{Phytophtora infestans}. Here, we present a multi-environmental analysis of the response to \textit{P. infestans} using an association panel of 150 accessions of \textit{S. tuberosum} Group Phureja, evaluated in two localities in Colombia. Disease resistance data were merged with a genotyping matrix of 83,862 SNPs obtained by 2b-restriction site–associated DNA and Genotyping by sequencing approaches into a Genome-wide association study. We are reporting 16 organ-specific QTL conferring resistance to late blight. These QTL explain from 13.7\% to 50.9\% of the phenotypic variance. Six and ten QTL were detected for resistance response in leaves and stem, respectively. \textit{In silico} analysis revealed 15 candidate genes for resistance to late blight. Four of them have no functional genome annotation, while eleven candidate genes code for diverse proteins, including one leucine-rich repeat kinase.{\textless}/p{\textgreater}},
	language = {en},
	urldate = {2020-07-02},
	journal = {bioRxiv},
	author = {Rojas, Deissy Katherine Juyo and Sedano, Johana Carolina Soto and Ballvora, Agim and Léon, Jens and Vásquez, Teresa Mosquera},
	month = mar,
	year = {2019},
	note = {Publisher: Cold Spring Harbor Laboratory
Section: New Results},
	pages = {31}
}

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The main limiting and destructive disease of potato is late blight, caused by <i>Phytophtora infestans</i>. Here, we present a multi-environmental analysis of the response to <i>P. infestans</i> using an association panel of 150 accessions of <i>S. tuberosum</i> Group Phureja, evaluated in two localities in Colombia. Disease resistance data were merged with a genotyping matrix of 83,862 SNPs obtained by 2b-restriction site–associated DNA and Genotyping by sequencing approaches into a Genome-wide association study. We are reporting 16 organ-specific QTL conferring resistance to late blight. These QTL explain from 13.7% to 50.9% of the phenotypic variance. Six and ten QTL were detected for resistance response in leaves and stem, respectively. <i>In silico</i> analysis revealed 15 candidate genes for resistance to late blight. Four of them have no functional genome annotation, while eleven candidate genes code for diverse proteins, including one leucine-rich repeat kinase.\\textless/p\\textgreater","language":"en","urldate":"2020-07-02","journal":"bioRxiv","author":[{"propositions":[],"lastnames":["Rojas"],"firstnames":["Deissy","Katherine","Juyo"],"suffixes":[]},{"propositions":[],"lastnames":["Sedano"],"firstnames":["Johana","Carolina","Soto"],"suffixes":[]},{"propositions":[],"lastnames":["Ballvora"],"firstnames":["Agim"],"suffixes":[]},{"propositions":[],"lastnames":["Léon"],"firstnames":["Jens"],"suffixes":[]},{"propositions":[],"lastnames":["Vásquez"],"firstnames":["Teresa","Mosquera"],"suffixes":[]}],"month":"March","year":"2019","note":"Publisher: Cold Spring Harbor Laboratory Section: New Results","pages":"31","bibtex":"@article{rojas_novel_2019,\n\ttitle = {Novel {Organ}-{Specific} {Genetic} {Factors} for {Quantitative} {Resistance} to {Late} {Blight} in {Potato}},\n\tcopyright = {© 2019, Posted by Cold Spring Harbor Laboratory. This pre-print is available under a Creative Commons License (Attribution 4.0 International), CC BY 4.0, as described at http://creativecommons.org/licenses/by/4.0/},\n\turl = {https://www.biorxiv.org/content/biorxiv/early/2019/03/04/567289.full.pdf},\n\tdoi = {10.1101/567289},\n\tabstract = {{\\textless}h3{\\textgreater}Abstract{\\textless}/h3{\\textgreater} {\\textless}p{\\textgreater}Potato, \\textit{Solanum tuberosum}, is one of the highest consumed food in the world, being the basis of the diet of millions of people. The main limiting and destructive disease of potato is late blight, caused by \\textit{Phytophtora infestans}. Here, we present a multi-environmental analysis of the response to \\textit{P. infestans} using an association panel of 150 accessions of \\textit{S. tuberosum} Group Phureja, evaluated in two localities in Colombia. Disease resistance data were merged with a genotyping matrix of 83,862 SNPs obtained by 2b-restriction site–associated DNA and Genotyping by sequencing approaches into a Genome-wide association study. We are reporting 16 organ-specific QTL conferring resistance to late blight. These QTL explain from 13.7\\% to 50.9\\% of the phenotypic variance. Six and ten QTL were detected for resistance response in leaves and stem, respectively. \\textit{In silico} analysis revealed 15 candidate genes for resistance to late blight. 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