Psychiatric comorbidities and therapeutic management in opiate-dependent patients undergoing a replacement therapy program in Spain: the Proteus study. Roncero, C., Box, B., Fuste, G., Barral, C., Llaudó, J., Eiroa-Orosa, F., López, C., & Casas, M. In European Psychiatry special issue: European Psychiatric Association 18th European Congress of Psychiatry, volume 25, pages 1323, 1, 2010.
Psychiatric comorbidities and therapeutic management in opiate-dependent patients undergoing a replacement therapy program in Spain: the Proteus study [pdf]Paper  Psychiatric comorbidities and therapeutic management in opiate-dependent patients undergoing a replacement therapy program in Spain: the Proteus study [link]Website  abstract   bibtex   
Introduction According to 2008 data, there are 80.000 patients undergoing replacement opiate programs (RMP) in Spain. However, the clinical therapeutic management and the psychiatric and medical comorbidities have not been well described. Objectives To describe the current therapeutic management and psychiatric comorbilities of opiate-dependent patients undergoing a RMP in Spain. Methods We carried out an observational, cross-sectional, multicenter study from September 2008 to February 2009. Patients > 18 years, with written informed consent, with a opiate-dependence according to DSM-IV-TR criteria and currently scheduled in a RMP in Spain were included. Results 624 patients (38.89±7.95 y.o.,84% men) were included in the study from 74 centers.

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