@article{roos_change_2008,
	title = {Change in self-reported outcomes and objective physical function over 7 years in middle-aged subjects with or at high risk of knee osteoarthritis},
	volume = {67},
	issn = {1468-2060},
	doi = {10.1136/ard.2007.074088},
	abstract = {{OBJECTIVE}: In the present work, we describe the clinical course and predictors of change in self-reported outcomes and objectively assessed physical function over time in middle-aged subjects at high risk of, or with knee osteoarthritis ({OA}).
{METHODS}: We examined 259 subjects (mean ({SD}) age 52.6 (10.4)) at mean 18 and 25 years after previous meniscectomy and 50 population-based age- and sex-matched reference subjects with the Knee injury and Osteoarthritis Outcome Score ({KOOS}), one-leg hop for distance and number of knee-bendings in 30 s. Radiographic {OA} was defined as equivalent to Kellgren and Lawrence grade 2 or worse.
{RESULTS}: At first assessment, meniscectomised subjects reported worse pain, function and quality of life compared with the reference group (p{\textless}0.001). They also performed fewer knee-bendings per 30 s (27 vs 31, p = 0.02). The meniscectomised patients worsened over the 4-10-year observation time in all measured outcomes (p{\textless}0.001), and to a greater extent than the reference group in pain (-5, 95\% {CI} -10 to 0) and one-leg hop (-11, 95\% {CI} -18 to -3). Being a woman, or having radiographic knee {OA}, enhanced the worsening in self-reported and objectively assessed outcomes. Older age and a higher body mass index ({BMI}) influenced objectively assessed physical function, but not self-reported outcomes.
{CONCLUSION}: Worsening over time in knee-related pain and function is greater in meniscectomised subjects compared with reference subjects. Rehabilitative efforts may be warranted in middle-aged meniscectomised patients, especially in women and those who have developed radiographic knee {OA}, who are at greater risk of worsening.},
	pages = {505--510},
	number = {4},
	journaltitle = {Annals of the Rheumatic Diseases},
	shortjournal = {Ann. Rheum. Dis.},
	author = {Roos, E. M. and Bremander, A. B. and Englund, M. and Lohmander, L. S.},
	date = {2008-04},
	pmid = {17704069},
	keywords = {Adult, Age Factors, Disease Progression, Female, Follow-Up Studies, Humans, Knee Joint, Male, Menisci, Tibial, Middle Aged, Osteoarthritis, Knee, Postoperative Complications, Prognosis, Quality of Life, Risk Factors, Severity of Illness Index}
}

{"_id":"sSBxYgavnfkFnz6nf","bibbaseid":"roos-bremander-englund-lohmander-changeinselfreportedoutcomesandobjectivephysicalfunctionover7yearsinmiddleagedsubjectswithorathighriskofkneeosteoarthritis","downloads":0,"creationDate":"2017-03-31T11:02:37.150Z","title":"Change in self-reported outcomes and objective physical function over 7 years in middle-aged subjects with or at high risk of knee osteoarthritis","author_short":["Roos, E. M.","Bremander, A. B.","Englund, M.","Lohmander, L. S."],"year":null,"bibtype":"article","biburl":"http://clinicalepidemiology.se/ClinEpi_LU.bib","bibdata":{"bibtype":"article","type":"article","title":"Change in self-reported outcomes and objective physical function over 7 years in middle-aged subjects with or at high risk of knee osteoarthritis","volume":"67","issn":"1468-2060","doi":"10.1136/ard.2007.074088","abstract":"OBJECTIVE: In the present work, we describe the clinical course and predictors of change in self-reported outcomes and objectively assessed physical function over time in middle-aged subjects at high risk of, or with knee osteoarthritis (OA). METHODS: We examined 259 subjects (mean (SD) age 52.6 (10.4)) at mean 18 and 25 years after previous meniscectomy and 50 population-based age- and sex-matched reference subjects with the Knee injury and Osteoarthritis Outcome Score (KOOS), one-leg hop for distance and number of knee-bendings in 30 s. Radiographic OA was defined as equivalent to Kellgren and Lawrence grade 2 or worse. RESULTS: At first assessment, meniscectomised subjects reported worse pain, function and quality of life compared with the reference group (p\\textless0.001). They also performed fewer knee-bendings per 30 s (27 vs 31, p = 0.02). The meniscectomised patients worsened over the 4-10-year observation time in all measured outcomes (p\\textless0.001), and to a greater extent than the reference group in pain (-5, 95% CI -10 to 0) and one-leg hop (-11, 95% CI -18 to -3). Being a woman, or having radiographic knee OA, enhanced the worsening in self-reported and objectively assessed outcomes. Older age and a higher body mass index (BMI) influenced objectively assessed physical function, but not self-reported outcomes. CONCLUSION: Worsening over time in knee-related pain and function is greater in meniscectomised subjects compared with reference subjects. Rehabilitative efforts may be warranted in middle-aged meniscectomised patients, especially in women and those who have developed radiographic knee OA, who are at greater risk of worsening.","pages":"505--510","number":"4","journaltitle":"Annals of the Rheumatic Diseases","shortjournal":"Ann. Rheum. Dis.","author":[{"propositions":[],"lastnames":["Roos"],"firstnames":["E.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Bremander"],"firstnames":["A.","B."],"suffixes":[]},{"propositions":[],"lastnames":["Englund"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Lohmander"],"firstnames":["L.","S."],"suffixes":[]}],"date":"2008-04","pmid":"17704069","keywords":"Adult, Age Factors, Disease Progression, Female, Follow-Up Studies, Humans, Knee Joint, Male, Menisci, Tibial, Middle Aged, Osteoarthritis, Knee, Postoperative Complications, Prognosis, Quality of Life, Risk Factors, Severity of Illness Index","bibtex":"@article{roos_change_2008,\n\ttitle = {Change in self-reported outcomes and objective physical function over 7 years in middle-aged subjects with or at high risk of knee osteoarthritis},\n\tvolume = {67},\n\tissn = {1468-2060},\n\tdoi = {10.1136/ard.2007.074088},\n\tabstract = {{OBJECTIVE}: In the present work, we describe the clinical course and predictors of change in self-reported outcomes and objectively assessed physical function over time in middle-aged subjects at high risk of, or with knee osteoarthritis ({OA}).\n{METHODS}: We examined 259 subjects (mean ({SD}) age 52.6 (10.4)) at mean 18 and 25 years after previous meniscectomy and 50 population-based age- and sex-matched reference subjects with the Knee injury and Osteoarthritis Outcome Score ({KOOS}), one-leg hop for distance and number of knee-bendings in 30 s. Radiographic {OA} was defined as equivalent to Kellgren and Lawrence grade 2 or worse.\n{RESULTS}: At first assessment, meniscectomised subjects reported worse pain, function and quality of life compared with the reference group (p{\\textless}0.001). They also performed fewer knee-bendings per 30 s (27 vs 31, p = 0.02). The meniscectomised patients worsened over the 4-10-year observation time in all measured outcomes (p{\\textless}0.001), and to a greater extent than the reference group in pain (-5, 95\\% {CI} -10 to 0) and one-leg hop (-11, 95\\% {CI} -18 to -3). Being a woman, or having radiographic knee {OA}, enhanced the worsening in self-reported and objectively assessed outcomes. Older age and a higher body mass index ({BMI}) influenced objectively assessed physical function, but not self-reported outcomes.\n{CONCLUSION}: Worsening over time in knee-related pain and function is greater in meniscectomised subjects compared with reference subjects. Rehabilitative efforts may be warranted in middle-aged meniscectomised patients, especially in women and those who have developed radiographic knee {OA}, who are at greater risk of worsening.},\n\tpages = {505--510},\n\tnumber = {4},\n\tjournaltitle = {Annals of the Rheumatic Diseases},\n\tshortjournal = {Ann. Rheum. Dis.},\n\tauthor = {Roos, E. M. and Bremander, A. B. and Englund, M. and Lohmander, L. S.},\n\tdate = {2008-04},\n\tpmid = {17704069},\n\tkeywords = {Adult, Age Factors, Disease Progression, Female, Follow-Up Studies, Humans, Knee Joint, Male, Menisci, Tibial, Middle Aged, Osteoarthritis, Knee, Postoperative Complications, Prognosis, Quality of Life, Risk Factors, Severity of Illness Index}\n}\n\n","author_short":["Roos, E. M.","Bremander, A. B.","Englund, M.","Lohmander, L. 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