Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk. Roosens, L., D'Hollander, W., Bervoets, L., Reynders, H., Van Campenhout, K., Cornelis, C., Van Den Heuvel, R., Koppen, G., & Covaci, A. Environmental pollution (Barking, Essex : 1987), 158(8):2546--52, August, 2010.
Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk. [link]Paper  doi  abstract   bibtex   
We assessed the exposure of the Flemish population to brominated flame retardants (BFRs) and perfluorinated compounds (PFCs) by analysis of pooled cord blood, adolescent and adult serum, and human milk. Levels of polybrominated diphenyl ethers (PBDEs) in blood (range 1.6-6.5 ng/g lipid weight, lw) and milk (range 2.0-6.4 ng/g lw) agreed with European data. Hexabromocyclododecane ranged between \textbackslashtextless2.1-5.7 ng/g lw in milk. Perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) dominated in blood and ranged between 1 and 171 ng/mL and \textbackslashtextless0.9-9.5 ng/mL, respectively. Total PFC levels in milk ranged between \textbackslashtextless0.5-29 ng/mL. A significant increase in PBDE concentrations was detected from newborns (median 2.1) to the adolescents and adults (medians 3.8 and 4.6 ng/g lw, respectively). An identical trend was observed for PFOS, but not for PFOA. We estimated that newborn exposure to BFRs and PFCs occurs predominantly post-natally, whereas placental transfer has a minor impact on the body burden.
@article{roosens_brominated_2010,
	title = {Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in {Belgian} human blood and milk.},
	volume = {158},
	issn = {1873-6424},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/20573431},
	doi = {10.1016/j.envpol.2010.05.022},
	abstract = {We assessed the exposure of the Flemish population to brominated flame retardants (BFRs) and perfluorinated compounds (PFCs) by analysis of pooled cord blood, adolescent and adult serum, and human milk. Levels of polybrominated diphenyl ethers (PBDEs) in blood (range 1.6-6.5 ng/g lipid weight, lw) and milk (range 2.0-6.4 ng/g lw) agreed with European data. Hexabromocyclododecane ranged between {\textbackslash}textless2.1-5.7 ng/g lw in milk. Perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) dominated in blood and ranged between 1 and 171 ng/mL and {\textbackslash}textless0.9-9.5 ng/mL, respectively. Total PFC levels in milk ranged between {\textbackslash}textless0.5-29 ng/mL. A significant increase in PBDE concentrations was detected from newborns (median 2.1) to the adolescents and adults (medians 3.8 and 4.6 ng/g lw, respectively). An identical trend was observed for PFOS, but not for PFOA. We estimated that newborn exposure to BFRs and PFCs occurs predominantly post-natally, whereas placental transfer has a minor impact on the body burden.},
	number = {8},
	journal = {Environmental pollution (Barking, Essex : 1987)},
	author = {Roosens, Laurence and D'Hollander, Wendy and Bervoets, Lieven and Reynders, Hans and Van Campenhout, Karen and Cornelis, Christa and Van Den Heuvel, Rosette and Koppen, Gudrun and Covaci, Adrian},
	month = aug,
	year = {2010},
	pmid = {20573431},
	keywords = {Adolescent, Adult, Aged, Alkanesulfonic Acids, Alkanesulfonic Acids: blood, Alkanesulfonic Acids: metabolism, Belgium, Brominated, Brominated: blood, Brominated: metabolism, Caprylates, Caprylates: blood, Caprylates: metabolism, Environmental Exposure, Environmental Exposure: analysis, Environmental Exposure: statistics \& numerical dat, Environmental Monitoring, Environmental Pollutants, Environmental Pollutants: blood, Environmental Pollutants: metabolism, Environmental Pollution, Environmental Pollution: statistics \& numerical da, Female, Fetal Blood, Fetal Blood: metabolism, Flame Retardants: metabolism, Flame retardants, Fluorinated, Fluorinated: blood, Fluorinated: metabolism, Fluorocarbons, Fluorocarbons: blood, Fluorocarbons: metabolism, Halogenated Diphenyl Ethers, Halogenated Diphenyl Ethers: blood, Halogenated Diphenyl Ethers: metabolism, Human, Human: metabolism, Humans, Hydrocarbons, Infant, Male, Middle Aged, Milk, Newborn, Young Adult},
	pages = {2546--52}
}

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