Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects. Rousseau, A., Ayoubi, F., Deveaux, C., Charbit, B., Delmau, C., Christin-Maitre, S., Jaillon, P., Uzan, G., & Simon, T. Fertil Steril, 93(3):843–6, 2010. Paper abstract bibtex OBJECTIVE: To assess the level of circulating endothelial progenitor cells (CEPC) in cycling women compared with men and menopausal women. DESIGN: Controlled clinical study. SETTING: Healthy, nonsmoking volunteers. PATIENT(S): Twelve women, aged 18-40 years, with regular menstrual cycles, 12 menopausal women, and two groups of 12 age-matched men were recruited. Women did not receive any hormone therapy. INTERVENTION(S): Collection of 20 mL of peripheral blood. MAIN OUTCOME MEASURE(S): The number of CEPC, defined as (Lin-/7AAD-/CD34+/CD133+/KDR+) cells per 10(6) mononuclear cells (MNC), was measured by flow cytometry. RESULT(S): The number of CEPC was significantly higher in cycling women than in age-matched men and menopausal women (26.5 per 10(6) MNC vs. 10.5 per 10(6) MNC vs. 10 per 10(6) MNC, respectively). The number of CEPC was similar in menopausal women, age-matched, and young men. CONCLUSION(S): The number of CEPC is influenced by an age-gender interaction. This phenomenon may explain in part the better vascular repair and relative cardiovascular protection in younger women as compared with age-matched men.
@article{rousseau_impact_2010,
title = {Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects},
volume = {93},
issn = {1556-5653},
shorttitle = {Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects},
url = {http://dx.doi.org/10.1016/j.fertnstert.2008.10.062},
abstract = {OBJECTIVE: To assess the level of circulating endothelial progenitor cells (CEPC) in cycling women compared with men and menopausal women. DESIGN: Controlled clinical study. SETTING: Healthy, nonsmoking volunteers. PATIENT(S): Twelve women, aged 18-40 years, with regular menstrual cycles, 12 menopausal women, and two groups of 12 age-matched men were recruited. Women did not receive any hormone therapy. INTERVENTION(S): Collection of 20 mL of peripheral blood. MAIN OUTCOME MEASURE(S): The number of CEPC, defined as (Lin-/7AAD-/CD34+/CD133+/KDR+) cells per 10(6) mononuclear cells (MNC), was measured by flow cytometry. RESULT(S): The number of CEPC was significantly higher in cycling women than in age-matched men and menopausal women (26.5 per 10(6) MNC vs. 10.5 per 10(6) MNC vs. 10 per 10(6) MNC, respectively). The number of CEPC was similar in menopausal women, age-matched, and young men. CONCLUSION(S): The number of CEPC is influenced by an age-gender interaction. This phenomenon may explain in part the better vascular repair and relative cardiovascular protection in younger women as compared with age-matched men.},
number = {3},
journal = {Fertil Steril},
author = {Rousseau, Alexandra and Ayoubi, Fida and Deveaux, Christel and Charbit, Beny and Delmau, Catherine and Christin-Maitre, Sophie and Jaillon, Patrice and Uzan, Georges and Simon, Tabassome},
year = {2010},
pages = {843--6},
}
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PATIENT(S): Twelve women, aged 18-40 years, with regular menstrual cycles, 12 menopausal women, and two groups of 12 age-matched men were recruited. Women did not receive any hormone therapy. INTERVENTION(S): Collection of 20 mL of peripheral blood. MAIN OUTCOME MEASURE(S): The number of CEPC, defined as (Lin-/7AAD-/CD34+/CD133+/KDR+) cells per 10(6) mononuclear cells (MNC), was measured by flow cytometry. RESULT(S): The number of CEPC was significantly higher in cycling women than in age-matched men and menopausal women (26.5 per 10(6) MNC vs. 10.5 per 10(6) MNC vs. 10 per 10(6) MNC, respectively). The number of CEPC was similar in menopausal women, age-matched, and young men. CONCLUSION(S): The number of CEPC is influenced by an age-gender interaction. This phenomenon may explain in part the better vascular repair and relative cardiovascular protection in younger women as compared with age-matched men.","number":"3","journal":"Fertil Steril","author":[{"propositions":[],"lastnames":["Rousseau"],"firstnames":["Alexandra"],"suffixes":[]},{"propositions":[],"lastnames":["Ayoubi"],"firstnames":["Fida"],"suffixes":[]},{"propositions":[],"lastnames":["Deveaux"],"firstnames":["Christel"],"suffixes":[]},{"propositions":[],"lastnames":["Charbit"],"firstnames":["Beny"],"suffixes":[]},{"propositions":[],"lastnames":["Delmau"],"firstnames":["Catherine"],"suffixes":[]},{"propositions":[],"lastnames":["Christin-Maitre"],"firstnames":["Sophie"],"suffixes":[]},{"propositions":[],"lastnames":["Jaillon"],"firstnames":["Patrice"],"suffixes":[]},{"propositions":[],"lastnames":["Uzan"],"firstnames":["Georges"],"suffixes":[]},{"propositions":[],"lastnames":["Simon"],"firstnames":["Tabassome"],"suffixes":[]}],"year":"2010","pages":"843–6","bibtex":"@article{rousseau_impact_2010,\n\ttitle = {Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects},\n\tvolume = {93},\n\tissn = {1556-5653},\n\tshorttitle = {Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects},\n\turl = {http://dx.doi.org/10.1016/j.fertnstert.2008.10.062},\n\tabstract = {OBJECTIVE: To assess the level of circulating endothelial progenitor cells (CEPC) in cycling women compared with men and menopausal women. DESIGN: Controlled clinical study. SETTING: Healthy, nonsmoking volunteers. PATIENT(S): Twelve women, aged 18-40 years, with regular menstrual cycles, 12 menopausal women, and two groups of 12 age-matched men were recruited. Women did not receive any hormone therapy. INTERVENTION(S): Collection of 20 mL of peripheral blood. MAIN OUTCOME MEASURE(S): The number of CEPC, defined as (Lin-/7AAD-/CD34+/CD133+/KDR+) cells per 10(6) mononuclear cells (MNC), was measured by flow cytometry. RESULT(S): The number of CEPC was significantly higher in cycling women than in age-matched men and menopausal women (26.5 per 10(6) MNC vs. 10.5 per 10(6) MNC vs. 10 per 10(6) MNC, respectively). The number of CEPC was similar in menopausal women, age-matched, and young men. CONCLUSION(S): The number of CEPC is influenced by an age-gender interaction. This phenomenon may explain in part the better vascular repair and relative cardiovascular protection in younger women as compared with age-matched men.},\n\tnumber = {3},\n\tjournal = {Fertil Steril},\n\tauthor = {Rousseau, Alexandra and Ayoubi, Fida and Deveaux, Christel and Charbit, Beny and Delmau, Catherine and Christin-Maitre, Sophie and Jaillon, Patrice and Uzan, Georges and Simon, Tabassome},\n\tyear = {2010},\n\tpages = {843--6},\n}\n\n","author_short":["Rousseau, A.","Ayoubi, F.","Deveaux, C.","Charbit, B.","Delmau, C.","Christin-Maitre, S.","Jaillon, P.","Uzan, G.","Simon, T."],"key":"rousseau_impact_2010","id":"rousseau_impact_2010","bibbaseid":"rousseau-ayoubi-deveaux-charbit-delmau-christinmaitre-jaillon-uzan-etal-impactofageandgenderinteractiononcirculatingendothelialprogenitorcellsinhealthysubjects-2010","role":"author","urls":{"Paper":"http://dx.doi.org/10.1016/j.fertnstert.2008.10.062"},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"http://bibbase.org/zotero/biblioial","dataSources":["ftoP3zPyb2N3b9Noc"],"keywords":[],"search_terms":["impact","age","gender","interaction","circulating","endothelial","progenitor","cells","healthy","subjects","rousseau","ayoubi","deveaux","charbit","delmau","christin-maitre","jaillon","uzan","simon"],"title":"Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects","year":2010}