@article{sabia_alcohol_2014,
	title = {Alcohol consumption and cognitive decline in early old age.},
	volume = {82},
	url = {http://www.neurology.org/content/82/4/332.full},
	doi = {10.1212/WNL.0000000000000063},
	abstract = {OBJECTIVE:To examine the association between alcohol consumption in midlife and subsequent cognitive decline. METHODS:Data are from 5,054 men and 2,099 women from the Whitehall II cohort study with a mean age of 56 years (range 44-69 years) at first cognitive assessment. Alcohol consumption was assessed 3 times in the 10 years preceding the first cognitive assessment (1997-1999). Cognitive tests were repeated in 2002-2004 and 2007-2009. The cognitive test battery included 4 tests assessing memory and executive function; a global cognitive score summarized performances across these tests. Linear mixed models were used to assess the association between alcohol consumption and cognitive decline, expressed as z scores (mean = 0, SD = 1). RESULTS:In men, there were no differences in cognitive decline among alcohol abstainers, quitters, and light or moderate alcohol drinkers ({\textless}20 g/d). However, alcohol consumption \${\textbackslash}ge\$36 g/d was associated with faster decline in all cognitive domains compared with consumption between 0.1 and 19.9 g/d: mean difference (95\% confidence interval) in 10-year decline in the global cognitive score = -0.10 (-0.16, -0.04), executive function = -0.06 (-0.12, 0.00), and memory = -0.16 (-0.26, -0.05). In women, compared with those drinking 0.1 to 9.9 g/d of alcohol, 10-year abstainers showed faster decline in the global cognitive score (-0.21 [-0.37, -0.04]) and executive function (-0.17 [-0.32, -0.01]). CONCLUSIONS:Excessive alcohol consumption in men (\${\textbackslash}ge\$36 g/d) was associated with faster cognitive decline compared with light to moderate alcohol consumption.},
	language = {English},
	number = {4},
	journal = {Neurology},
	author = {Sabia, Séverine and Elbaz, Alexis and Britton, Annie and Bell, Steven and Dugravot, Aline and Shipley, Martin and Kivimaki, Mika and Singh-Manoux, Archana},
	month = jan,
	year = {2014},
	pmid = {24431298},
	pmcid = {PMC3929201},
	pages = {332--339},
}

{"_id":"HEiwgy4eRRjMQh6qZ","bibbaseid":"sabia-elbaz-britton-bell-dugravot-shipley-kivimaki-singhmanoux-alcoholconsumptionandcognitivedeclineinearlyoldage-2014","author_short":["Sabia, S.","Elbaz, A.","Britton, A.","Bell, S.","Dugravot, A.","Shipley, M.","Kivimaki, M.","Singh-Manoux, A."],"bibdata":{"bibtype":"article","type":"article","title":"Alcohol consumption and cognitive decline in early old age.","volume":"82","url":"http://www.neurology.org/content/82/4/332.full","doi":"10.1212/WNL.0000000000000063","abstract":"OBJECTIVE:To examine the association between alcohol consumption in midlife and subsequent cognitive decline. METHODS:Data are from 5,054 men and 2,099 women from the Whitehall II cohort study with a mean age of 56 years (range 44-69 years) at first cognitive assessment. Alcohol consumption was assessed 3 times in the 10 years preceding the first cognitive assessment (1997-1999). Cognitive tests were repeated in 2002-2004 and 2007-2009. The cognitive test battery included 4 tests assessing memory and executive function; a global cognitive score summarized performances across these tests. Linear mixed models were used to assess the association between alcohol consumption and cognitive decline, expressed as z scores (mean = 0, SD = 1). RESULTS:In men, there were no differences in cognitive decline among alcohol abstainers, quitters, and light or moderate alcohol drinkers (\\textless20 g/d). However, alcohol consumption ${\\}ge$36 g/d was associated with faster decline in all cognitive domains compared with consumption between 0.1 and 19.9 g/d: mean difference (95% confidence interval) in 10-year decline in the global cognitive score = -0.10 (-0.16, -0.04), executive function = -0.06 (-0.12, 0.00), and memory = -0.16 (-0.26, -0.05). In women, compared with those drinking 0.1 to 9.9 g/d of alcohol, 10-year abstainers showed faster decline in the global cognitive score (-0.21 [-0.37, -0.04]) and executive function (-0.17 [-0.32, -0.01]). CONCLUSIONS:Excessive alcohol consumption in men (${\\}ge$36 g/d) was associated with faster cognitive decline compared with light to moderate alcohol consumption.","language":"English","number":"4","journal":"Neurology","author":[{"propositions":[],"lastnames":["Sabia"],"firstnames":["Séverine"],"suffixes":[]},{"propositions":[],"lastnames":["Elbaz"],"firstnames":["Alexis"],"suffixes":[]},{"propositions":[],"lastnames":["Britton"],"firstnames":["Annie"],"suffixes":[]},{"propositions":[],"lastnames":["Bell"],"firstnames":["Steven"],"suffixes":[]},{"propositions":[],"lastnames":["Dugravot"],"firstnames":["Aline"],"suffixes":[]},{"propositions":[],"lastnames":["Shipley"],"firstnames":["Martin"],"suffixes":[]},{"propositions":[],"lastnames":["Kivimaki"],"firstnames":["Mika"],"suffixes":[]},{"propositions":[],"lastnames":["Singh-Manoux"],"firstnames":["Archana"],"suffixes":[]}],"month":"January","year":"2014","pmid":"24431298","pmcid":"PMC3929201","pages":"332–339","bibtex":"@article{sabia_alcohol_2014,\n\ttitle = {Alcohol consumption and cognitive decline in early old age.},\n\tvolume = {82},\n\turl = {http://www.neurology.org/content/82/4/332.full},\n\tdoi = {10.1212/WNL.0000000000000063},\n\tabstract = {OBJECTIVE:To examine the association between alcohol consumption in midlife and subsequent cognitive decline. METHODS:Data are from 5,054 men and 2,099 women from the Whitehall II cohort study with a mean age of 56 years (range 44-69 years) at first cognitive assessment. Alcohol consumption was assessed 3 times in the 10 years preceding the first cognitive assessment (1997-1999). Cognitive tests were repeated in 2002-2004 and 2007-2009. The cognitive test battery included 4 tests assessing memory and executive function; a global cognitive score summarized performances across these tests. Linear mixed models were used to assess the association between alcohol consumption and cognitive decline, expressed as z scores (mean = 0, SD = 1). RESULTS:In men, there were no differences in cognitive decline among alcohol abstainers, quitters, and light or moderate alcohol drinkers ({\\textless}20 g/d). However, alcohol consumption \\${\\textbackslash}ge\\$36 g/d was associated with faster decline in all cognitive domains compared with consumption between 0.1 and 19.9 g/d: mean difference (95\\% confidence interval) in 10-year decline in the global cognitive score = -0.10 (-0.16, -0.04), executive function = -0.06 (-0.12, 0.00), and memory = -0.16 (-0.26, -0.05). In women, compared with those drinking 0.1 to 9.9 g/d of alcohol, 10-year abstainers showed faster decline in the global cognitive score (-0.21 [-0.37, -0.04]) and executive function (-0.17 [-0.32, -0.01]). CONCLUSIONS:Excessive alcohol consumption in men (\\${\\textbackslash}ge\\$36 g/d) was associated with faster cognitive decline compared with light to moderate alcohol consumption.},\n\tlanguage = {English},\n\tnumber = {4},\n\tjournal = {Neurology},\n\tauthor = {Sabia, Séverine and Elbaz, Alexis and Britton, Annie and Bell, Steven and Dugravot, Aline and Shipley, Martin and Kivimaki, Mika and Singh-Manoux, Archana},\n\tmonth = jan,\n\tyear = {2014},\n\tpmid = {24431298},\n\tpmcid = {PMC3929201},\n\tpages = {332--339},\n}\n\n","author_short":["Sabia, S.","Elbaz, A.","Britton, A.","Bell, S.","Dugravot, A.","Shipley, M.","Kivimaki, M.","Singh-Manoux, A."],"key":"sabia_alcohol_2014","id":"sabia_alcohol_2014","bibbaseid":"sabia-elbaz-britton-bell-dugravot-shipley-kivimaki-singhmanoux-alcoholconsumptionandcognitivedeclineinearlyoldage-2014","role":"author","urls":{"Paper":"http://www.neurology.org/content/82/4/332.full"},"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/kountour","dataSources":["MnayAXw3qciX87bz7"],"keywords":[],"search_terms":["alcohol","consumption","cognitive","decline","early","old","age","sabia","elbaz","britton","bell","dugravot","shipley","kivimaki","singh-manoux"],"title":"Alcohol consumption and cognitive decline in early old age.","year":2014}