Magnetic resonance elastography and diffusion-weighted imaging of the sol/gel phase transition in agarose. Sack, I., Gedat, E., Bernarding, J., Buntkowsky, G., & Braun, J.R. J Magn Reson, 166(2):252--261, Feb, 2004. abstract bibtex The dynamics of the sol/gel phase transition in agarose was analyzed with magnetic resonance elastography (MRE) and diffusion-weighted imaging, providing complementary information on a microstructural as well as on a macroscopic spatial scale. In thermal equilibrium, the diffusion coefficient of agarose is linearly correlated with temperature, independent of the sol/gel phase transition. In larger agarose samples, the transition from the sol to the gel state was characterized by a complex position and temperature dependency of both MRE shear wave patterns and apparent diffusion coefficients (ADC). The position dependency of the temperature was experimentally found to be qualitatively similar to the behavior of the ADC maps. The dynamics of the temperature could be described with a simplified model that described the heat exchange between sol and gel compartments. The experiments supported the approach to derive temperature maps from the ADC maps by a linear relationship. The spatially resolved dynamics of the temperature maps were therefore employed to determine the elasticities. For this reason, experimental MRE data were simulated using a model of coupled harmonic oscillators. The calculated images agreed well with the experimentally observed MRE wave patterns.
@article{ Sack2004a,
author = {Sack, Ingolf and Gedat, Egbert and Bernarding, Johannes and Buntkowsky,
Gerd and Braun, J�rgen},
title = {Magnetic resonance elastography and diffusion-weighted imaging of
the sol/gel phase transition in agarose.},
journal = {J Magn Reson},
year = {2004},
volume = {166},
pages = {252--261},
number = {2},
month = {Feb},
abstract = {The dynamics of the sol/gel phase transition in agarose was analyzed
with magnetic resonance elastography (MRE) and diffusion-weighted
imaging, providing complementary information on a microstructural
as well as on a macroscopic spatial scale. In thermal equilibrium,
the diffusion coefficient of agarose is linearly correlated with
temperature, independent of the sol/gel phase transition. In larger
agarose samples, the transition from the sol to the gel state was
characterized by a complex position and temperature dependency of
both MRE shear wave patterns and apparent diffusion coefficients
(ADC). The position dependency of the temperature was experimentally
found to be qualitatively similar to the behavior of the ADC maps.
The dynamics of the temperature could be described with a simplified
model that described the heat exchange between sol and gel compartments.
The experiments supported the approach to derive temperature maps
from the ADC maps by a linear relationship. The spatially resolved
dynamics of the temperature maps were therefore employed to determine
the elasticities. For this reason, experimental MRE data were simulated
using a model of coupled harmonic oscillators. The calculated images
agreed well with the experimentally observed MRE wave patterns.},
institution = {Department of Medical Informatics, Charit�-University Medicine Berlin,
Campus Benjamin Franklin, Hindenburgdamm 30, D-12200 Berlin, Germany.},
keywords = {Elasticity; Gels; Magnetic Resonance Imaging, methods; Phantoms, Imaging;
Sepharose, chemistry; Temperature},
language = {eng},
medline-pst = {ppublish},
owner = {Heiko},
pii = {S1090780703003732},
pmid = {14729037},
timestamp = {2013.07.26}
}
Downloads: 0
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[bib]\" \n\t class=\"bibbase_icon\"\n\t style=\"width: 24px; height: 24px; border: 0px; vertical-align: text-top\"><span class=\"bibbase_icon_text\">Bibtex</span></a>\n \n \n\n \n \n \n \n \n\n \n <a class=\"bibbase_abstract_link\" href=\"javascript:showAbstract('Sack2004a')\">Abstract</a>\n \n \n</span>\n\n<!-- -->\n<!-- <div id=\"abstract_Sack2004a\"> -->\n<!-- The dynamics of the sol/gel phase transition in agarose was analyzed with magnetic resonance elastography (MRE) and diffusion-weighted imaging, providing complementary information on a microstructural as well as on a macroscopic spatial scale. In thermal equilibrium, the diffusion coefficient of agarose is linearly correlated with temperature, independent of the sol/gel phase transition. In larger agarose samples, the transition from the sol to the gel state was characterized by a complex position and temperature dependency of both MRE shear wave patterns and apparent diffusion coefficients (ADC). The position dependency of the temperature was experimentally found to be qualitatively similar to the behavior of the ADC maps. The dynamics of the temperature could be described with a simplified model that described the heat exchange between sol and gel compartments. The experiments supported the approach to derive temperature maps from the ADC maps by a linear relationship. The spatially resolved dynamics of the temperature maps were therefore employed to determine the elasticities. For this reason, experimental MRE data were simulated using a model of coupled harmonic oscillators. The calculated images agreed well with the experimentally observed MRE wave patterns. -->\n<!-- </div> -->\n<!-- -->\n\n</div>\n","downloads":0,"abstract":"The dynamics of the sol/gel phase transition in agarose was analyzed with magnetic resonance elastography (MRE) and diffusion-weighted imaging, providing complementary information on a microstructural as well as on a macroscopic spatial scale. In thermal equilibrium, the diffusion coefficient of agarose is linearly correlated with temperature, independent of the sol/gel phase transition. In larger agarose samples, the transition from the sol to the gel state was characterized by a complex position and temperature dependency of both MRE shear wave patterns and apparent diffusion coefficients (ADC). The position dependency of the temperature was experimentally found to be qualitatively similar to the behavior of the ADC maps. The dynamics of the temperature could be described with a simplified model that described the heat exchange between sol and gel compartments. The experiments supported the approach to derive temperature maps from the ADC maps by a linear relationship. The spatially resolved dynamics of the temperature maps were therefore employed to determine the elasticities. For this reason, experimental MRE data were simulated using a model of coupled harmonic oscillators. The calculated images agreed well with the experimentally observed MRE wave patterns.","author":["Sack, Ingolf","Gedat, Egbert","Bernarding, Johannes","Buntkowsky, Gerd","Braun, J�rgen"],"author_short":["Sack, I.","Gedat, E.","Bernarding, J.","Buntkowsky, G.","Braun, J.R."],"bibtex":"@article{ Sack2004a,\n author = {Sack, Ingolf and Gedat, Egbert and Bernarding, Johannes and Buntkowsky,\r\n\tGerd and Braun, J�rgen},\n title = {Magnetic resonance elastography and diffusion-weighted imaging of\r\n\tthe sol/gel phase transition in agarose.},\n journal = {J Magn Reson},\n year = {2004},\n volume = {166},\n pages = {252--261},\n number = {2},\n month = {Feb},\n abstract = {The dynamics of the sol/gel phase transition in agarose was analyzed\r\n\twith magnetic resonance elastography (MRE) and diffusion-weighted\r\n\timaging, providing complementary information on a microstructural\r\n\tas well as on a macroscopic spatial scale. In thermal equilibrium,\r\n\tthe diffusion coefficient of agarose is linearly correlated with\r\n\ttemperature, independent of the sol/gel phase transition. In larger\r\n\tagarose samples, the transition from the sol to the gel state was\r\n\tcharacterized by a complex position and temperature dependency of\r\n\tboth MRE shear wave patterns and apparent diffusion coefficients\r\n\t(ADC). The position dependency of the temperature was experimentally\r\n\tfound to be qualitatively similar to the behavior of the ADC maps.\r\n\tThe dynamics of the temperature could be described with a simplified\r\n\tmodel that described the heat exchange between sol and gel compartments.\r\n\tThe experiments supported the approach to derive temperature maps\r\n\tfrom the ADC maps by a linear relationship. The spatially resolved\r\n\tdynamics of the temperature maps were therefore employed to determine\r\n\tthe elasticities. For this reason, experimental MRE data were simulated\r\n\tusing a model of coupled harmonic oscillators. The calculated images\r\n\tagreed well with the experimentally observed MRE wave patterns.},\n institution = {Department of Medical Informatics, Charit�-University Medicine Berlin,\r\n\tCampus Benjamin Franklin, Hindenburgdamm 30, D-12200 Berlin, Germany.},\n keywords = {Elasticity; Gels; Magnetic Resonance Imaging, methods; Phantoms, Imaging;\r\n\tSepharose, chemistry; Temperature},\n language = {eng},\n medline-pst = {ppublish},\n owner = {Heiko},\n pii = {S1090780703003732},\n pmid = {14729037},\n timestamp = {2013.07.26}\n}","bibtype":"article","id":"Sack2004a","institution":"Department of Medical Informatics, Charit�-University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D-12200 Berlin, Germany.","journal":"J Magn Reson","key":"Sack2004a","keywords":"Elasticity; Gels; Magnetic Resonance Imaging, methods; Phantoms, Imaging; Sepharose, chemistry; Temperature","language":"eng","medline-pst":"ppublish","month":"Feb","number":"2","owner":"Heiko","pages":"252--261","pii":"S1090780703003732","pmid":"14729037","timestamp":"2013.07.26","title":"Magnetic resonance elastography and diffusion-weighted imaging of the sol/gel phase transition in agarose.","type":"article","volume":"166","year":"2004","role":"author","urls":{},"bibbaseid":"sack-gedat-bernarding-buntkowsky-braun-magneticresonanceelastographyanddiffusionweightedimagingofthesolgelphasetransitioninagarose-2004"},"bibtype":"article","biburl":"http://home.arcor.de/teambushido/Literatur.bib","downloads":0,"title":"Magnetic resonance elastography and diffusion-weighted imaging of the sol/gel phase transition in agarose.","year":2004,"dataSources":["z828pEjP7GR5ew7B7"]}