Different risk factor profiles distinguish early-onset from late-onset. Schachtner, T., Babel, N., & Reinke, P. Transplant international : official journal of the European Society for Organ Transplantation, 28(9):1081--1091, September, 2015.
doi  abstract   bibtex   
Two of three reactivations of latent BKV-infection occur within the first 6 months after renal transplantation. However, a clear differentiation between early-onset and late-onset BKV-replication is lacking. Here, we studied all kidney transplant recipients (KTRs) at our single transplant center between 2004 and 2012. A total of 103 of 862 KTRs were diagnosed with BK viremia (11.9%), among which 24 KTRs (2.8%) showed progression to BKV-associated nephropathy (BKVN). Sixty-seven KTRs with early-onset BKV-replication (65%) and 36 KTRs with late-onset BKV-replication (35%) were identified. A control group of 598 KTRs without BKV-replication was used for comparison. Lymphocyte-depleting induction,
@article{schachtner_different_2015,
	title = {Different risk factor profiles distinguish early-onset from late-onset},
	volume = {28},
	copyright = {(c) 2015 Steunstichting ESOT.},
	issn = {1432-2277 0934-0874},
	doi = {10.1111/tri.12601},
	abstract = {Two of three reactivations of latent BKV-infection occur within the first 6 months after renal transplantation. However, a clear differentiation between early-onset and late-onset BKV-replication is lacking. Here, we studied all kidney transplant recipients (KTRs) at our single transplant center between 2004  and 2012. A total of 103 of 862 KTRs were diagnosed with BK viremia (11.9\%), among which 24 KTRs (2.8\%) showed progression to BKV-associated nephropathy (BKVN). Sixty-seven KTRs with early-onset BKV-replication (65\%) and 36 KTRs with  late-onset BKV-replication (35\%) were identified. A control group of 598 KTRs without BKV-replication was used for comparison. Lymphocyte-depleting induction,},
	language = {eng},
	number = {9},
	journal = {Transplant international : official journal of the European Society for Organ Transplantation},
	author = {Schachtner, Thomas and Babel, Nina and Reinke, Petra},
	month = sep,
	year = {2015},
	pmid = {25959355},
	keywords = {Adolescent, Adult, Aged, BK Virus, BK polyomavirus, CMV, Creatinine/blood, Disease Progression, Female, Graft Rejection, Humans, Immunosuppression, Immunosuppressive Agents/therapeutic use, Inflammation, Kidney Transplantation/*adverse effects, Male, Middle Aged, Polymerase Chain Reaction, Polyomavirus Infections/etiology, Renal Insufficiency/complications/*surgery, Retrospective Studies, Risk Factors, Treatment Outcome, Virus Replication, Young Adult, renal transplantation},
	pages = {1081--1091}
}

Downloads: 0