From immune surveillance to tumor-immune escape: the story of an enemy with multiple strategies of resistance and counterattack. Scharovsky, O G, Matar, P, Fluck, M Z, Rico, M J, & Rabinovich, G A 25(2):14, 2006. abstract bibtex Tumors must circumvent the immune response of the host to become clinically detectable. For this purpose, malignant cells have devised multiple strategies to thwart immune attack. These mechanisms are suggested to conspire in advanced stages of cancer to limit the ability of the immune system to restrain the tumor and the effectiveness of immunotherapy strategies to successfully eradicate malignant cells. From tumor biology to cancer immunotherapy and back again, we will summarize here some of the most important mechanisms used by tumors to evade the immune response and their potential impact in the design of cancer immunotherapy strategies.
@article{scharovsky_immune_2006,
title = {From immune surveillance to tumor-immune escape: the story of an enemy with multiple strategies of resistance and counterattack},
volume = {25},
abstract = {Tumors must circumvent the immune response of the host to become clinically detectable. For this purpose, malignant cells have devised multiple strategies to thwart immune attack. These mechanisms are suggested to conspire in advanced stages of cancer to limit the ability of the immune system to restrain the tumor and the effectiveness of immunotherapy strategies to successfully eradicate malignant cells. From tumor biology to cancer immunotherapy and back again, we will summarize here some of the most important mechanisms used by tumors to evade the immune response and their potential impact in the design of cancer immunotherapy strategies.},
language = {en},
number = {2},
author = {Scharovsky, O G and Matar, P and Fluck, M Z and Rico, M J and Rabinovich, G A},
year = {2006},
keywords = {Unfinished},
pages = {14},
}
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