Comparison of Chronologic Change in the Size and Contrast-Enhancement of Ablation Zones on CT Images after Irreversible Electroporation and Radiofrequency Ablation. Scheck, J., Bruners, P., Schindler, D., Kuhl, C., & Isfort, P. Korean Journal of Radiology, 19(4):560–567, 2018. ![Comparison of Chronologic Change in the Size and Contrast-Enhancement of Ablation Zones on CT Images after Irreversible Electroporation and Radiofrequency Ablation [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Objective To compare short-, mid-, and long-term follow-up ablation zone volume alterations as well as imaging features on contrast-enhanced computed tomography (CT) after irreversible electroporation (IRE) of primary and secondary liver tumors with findings subsequent to radiofrequency ablation (RFA). Materials and Methods Volume assessment of 39 ablation zones (19 RFA, 20 IRE) after intervention was performed at four time intervals (day 0 [t1; n = 39], day 1–7 [t2; n = 25], day 8–55 [t3; n = 28], after day 55 [t4; n = 23]) on dual-phase CT. Analysis of peripheral rim enhancement was conducted. Lesion's volume decrease relative to the volume at t1 was calculated and statistically analyzed with respect to patient's sex, age, ablation modality (IRE/RFA), and history of platinum-based chemotherapy (PCT). Results No influence of patient's sex or age on ablation volume was detected. The decrease in ablation zones' volume was significantly larger (p \textless 0.05 for all time intervals) after IRE (arterial phase, 7.5%; venous phase, 9.7% of initial volume) compared to RFA (arterial phase, 39.6%; venous phase, 45.3% of initial volume). After RFA, significantly smaller decreases in the ablation volumes, in general, were detected in patients treated with PCT in their history (p = 0.004), which was not detected after IRE (p = 0.288). In the arterial phase, peripheral rim enhancement was frequently detected after both IRE and RFA. In the venous phase, rim-enhancement was depicted significantly more often following IRE at t1 and t2 (pt1 = 0.003, pt2 \textless 0.001). Conclusion As per our analysis, ablation zone volume decreased significantly in a more rapid and more profound manner after IRE. Lesion's remodeling after RFA but not IRE seems to be influenced by PCT, possibly due to the type of cell death induced by the different ablation modalities.
@article{scheck_comparison_2018,
title = {Comparison of {Chronologic} {Change} in the {Size} and {Contrast}-{Enhancement} of {Ablation} {Zones} on {CT} {Images} after {Irreversible} {Electroporation} and {Radiofrequency} {Ablation}},
volume = {19},
issn = {1229-6929},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005936/},
doi = {10.3348/kjr.2018.19.4.560},
abstract = {Objective
To compare short-, mid-, and long-term follow-up ablation zone volume alterations as well as imaging features on contrast-enhanced computed tomography (CT) after irreversible electroporation (IRE) of primary and secondary liver tumors with findings subsequent to radiofrequency ablation (RFA).
Materials and Methods
Volume assessment of 39 ablation zones (19 RFA, 20 IRE) after intervention was performed at four time intervals (day 0 [t1; n = 39], day 1–7 [t2; n = 25], day 8–55 [t3; n = 28], after day 55 [t4; n = 23]) on dual-phase CT. Analysis of peripheral rim enhancement was conducted. Lesion's volume decrease relative to the volume at t1 was calculated and statistically analyzed with respect to patient's sex, age, ablation modality (IRE/RFA), and history of platinum-based chemotherapy (PCT).
Results
No influence of patient's sex or age on ablation volume was detected. The decrease in ablation zones' volume was significantly larger (p {\textless} 0.05 for all time intervals) after IRE (arterial phase, 7.5\%; venous phase, 9.7\% of initial volume) compared to RFA (arterial phase, 39.6\%; venous phase, 45.3\% of initial volume). After RFA, significantly smaller decreases in the ablation volumes, in general, were detected in patients treated with PCT in their history (p = 0.004), which was not detected after IRE (p = 0.288). In the arterial phase, peripheral rim enhancement was frequently detected after both IRE and RFA. In the venous phase, rim-enhancement was depicted significantly more often following IRE at t1 and t2 (pt1 = 0.003, pt2 {\textless} 0.001).
Conclusion
As per our analysis, ablation zone volume decreased significantly in a more rapid and more profound manner after IRE. Lesion's remodeling after RFA but not IRE seems to be influenced by PCT, possibly due to the type of cell death induced by the different ablation modalities.},
number = {4},
urldate = {2018-07-12},
journal = {Korean Journal of Radiology},
author = {Scheck, Jonas and Bruners, Philipp and Schindler, David and Kuhl, Christiane and Isfort, Peter},
year = {2018},
pmid = {29962862},
pmcid = {PMC6005936},
pages = {560--567},
}
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{"_id":"aeNu9M24967jGhoMT","bibbaseid":"scheck-bruners-schindler-kuhl-isfort-comparisonofchronologicchangeinthesizeandcontrastenhancementofablationzonesonctimagesafterirreversibleelectroporationandradiofrequencyablation-2018","downloads":0,"creationDate":"2019-03-08T19:02:46.352Z","title":"Comparison of Chronologic Change in the Size and Contrast-Enhancement of Ablation Zones on CT Images after Irreversible Electroporation and Radiofrequency Ablation","author_short":["Scheck, J.","Bruners, P.","Schindler, D.","Kuhl, C.","Isfort, P."],"year":2018,"bibtype":"article","biburl":"https://bibbase.org/zotero/sannpeterson","bibdata":{"bibtype":"article","type":"article","title":"Comparison of Chronologic Change in the Size and Contrast-Enhancement of Ablation Zones on CT Images after Irreversible Electroporation and Radiofrequency Ablation","volume":"19","issn":"1229-6929","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005936/","doi":"10.3348/kjr.2018.19.4.560","abstract":"Objective To compare short-, mid-, and long-term follow-up ablation zone volume alterations as well as imaging features on contrast-enhanced computed tomography (CT) after irreversible electroporation (IRE) of primary and secondary liver tumors with findings subsequent to radiofrequency ablation (RFA). Materials and Methods Volume assessment of 39 ablation zones (19 RFA, 20 IRE) after intervention was performed at four time intervals (day 0 [t1; n = 39], day 1–7 [t2; n = 25], day 8–55 [t3; n = 28], after day 55 [t4; n = 23]) on dual-phase CT. Analysis of peripheral rim enhancement was conducted. Lesion's volume decrease relative to the volume at t1 was calculated and statistically analyzed with respect to patient's sex, age, ablation modality (IRE/RFA), and history of platinum-based chemotherapy (PCT). Results No influence of patient's sex or age on ablation volume was detected. The decrease in ablation zones' volume was significantly larger (p \\textless 0.05 for all time intervals) after IRE (arterial phase, 7.5%; venous phase, 9.7% of initial volume) compared to RFA (arterial phase, 39.6%; venous phase, 45.3% of initial volume). After RFA, significantly smaller decreases in the ablation volumes, in general, were detected in patients treated with PCT in their history (p = 0.004), which was not detected after IRE (p = 0.288). In the arterial phase, peripheral rim enhancement was frequently detected after both IRE and RFA. In the venous phase, rim-enhancement was depicted significantly more often following IRE at t1 and t2 (pt1 = 0.003, pt2 \\textless 0.001). Conclusion As per our analysis, ablation zone volume decreased significantly in a more rapid and more profound manner after IRE. Lesion's remodeling after RFA but not IRE seems to be influenced by PCT, possibly due to the type of cell death induced by the different ablation modalities.","number":"4","urldate":"2018-07-12","journal":"Korean Journal of Radiology","author":[{"propositions":[],"lastnames":["Scheck"],"firstnames":["Jonas"],"suffixes":[]},{"propositions":[],"lastnames":["Bruners"],"firstnames":["Philipp"],"suffixes":[]},{"propositions":[],"lastnames":["Schindler"],"firstnames":["David"],"suffixes":[]},{"propositions":[],"lastnames":["Kuhl"],"firstnames":["Christiane"],"suffixes":[]},{"propositions":[],"lastnames":["Isfort"],"firstnames":["Peter"],"suffixes":[]}],"year":"2018","pmid":"29962862","pmcid":"PMC6005936","pages":"560–567","bibtex":"@article{scheck_comparison_2018,\n\ttitle = {Comparison of {Chronologic} {Change} in the {Size} and {Contrast}-{Enhancement} of {Ablation} {Zones} on {CT} {Images} after {Irreversible} {Electroporation} and {Radiofrequency} {Ablation}},\n\tvolume = {19},\n\tissn = {1229-6929},\n\turl = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005936/},\n\tdoi = {10.3348/kjr.2018.19.4.560},\n\tabstract = {Objective\nTo compare short-, mid-, and long-term follow-up ablation zone volume alterations as well as imaging features on contrast-enhanced computed tomography (CT) after irreversible electroporation (IRE) of primary and secondary liver tumors with findings subsequent to radiofrequency ablation (RFA).\n\nMaterials and Methods\nVolume assessment of 39 ablation zones (19 RFA, 20 IRE) after intervention was performed at four time intervals (day 0 [t1; n = 39], day 1–7 [t2; n = 25], day 8–55 [t3; n = 28], after day 55 [t4; n = 23]) on dual-phase CT. Analysis of peripheral rim enhancement was conducted. Lesion's volume decrease relative to the volume at t1 was calculated and statistically analyzed with respect to patient's sex, age, ablation modality (IRE/RFA), and history of platinum-based chemotherapy (PCT).\n\nResults\nNo influence of patient's sex or age on ablation volume was detected. The decrease in ablation zones' volume was significantly larger (p {\\textless} 0.05 for all time intervals) after IRE (arterial phase, 7.5\\%; venous phase, 9.7\\% of initial volume) compared to RFA (arterial phase, 39.6\\%; venous phase, 45.3\\% of initial volume). After RFA, significantly smaller decreases in the ablation volumes, in general, were detected in patients treated with PCT in their history (p = 0.004), which was not detected after IRE (p = 0.288). In the arterial phase, peripheral rim enhancement was frequently detected after both IRE and RFA. In the venous phase, rim-enhancement was depicted significantly more often following IRE at t1 and t2 (pt1 = 0.003, pt2 {\\textless} 0.001).\n\nConclusion\nAs per our analysis, ablation zone volume decreased significantly in a more rapid and more profound manner after IRE. Lesion's remodeling after RFA but not IRE seems to be influenced by PCT, possibly due to the type of cell death induced by the different ablation modalities.},\n\tnumber = {4},\n\turldate = {2018-07-12},\n\tjournal = {Korean Journal of Radiology},\n\tauthor = {Scheck, Jonas and Bruners, Philipp and Schindler, David and Kuhl, Christiane and Isfort, Peter},\n\tyear = {2018},\n\tpmid = {29962862},\n\tpmcid = {PMC6005936},\n\tpages = {560--567},\n}\n\n","author_short":["Scheck, J.","Bruners, P.","Schindler, D.","Kuhl, C.","Isfort, P."],"key":"scheck_comparison_2018","id":"scheck_comparison_2018","bibbaseid":"scheck-bruners-schindler-kuhl-isfort-comparisonofchronologicchangeinthesizeandcontrastenhancementofablationzonesonctimagesafterirreversibleelectroporationandradiofrequencyablation-2018","role":"author","urls":{"Paper":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005936/"},"downloads":0,"html":""},"search_terms":["comparison","chronologic","change","size","contrast","enhancement","ablation","zones","images","irreversible","electroporation","radiofrequency","ablation","scheck","bruners","schindler","kuhl","isfort"],"keywords":["ct","ire","minimally invasive therapy","rfa","tumor volume"],"authorIDs":[],"dataSources":["JPAoq8b4ppzXj5XYZ"]}