The effect of population history on the distribution of the Tajima’s D statistic. Schmidt, D. & Pool, J. abstract bibtex The Tajima’s D test measures the allele frequency distribution of nucleotide sequence data. This statistic can be influenced by both population history and natural selection. The purpose of this study is to distinguish between these two evolutionary forces. We observe the simulated distribution of Tajima’s D under an equilibrium model, an exponential growth model, and a population bottleneck model. We note the probability of rejection under Tajima’s published critical values, and subsequently generate a corrected set of critical values for each demographic scenario. Utilizing these adjusted values should increase the power and reduce the chance that demography will cause the rejection of the null hypothesis of the Tajima’s D test.
@article{schmidt_eect_nodate,
title = {The effect of population history on the distribution of the {Tajima}’s {D} statistic},
abstract = {The Tajima’s D test measures the allele frequency distribution of nucleotide sequence data. This statistic can be influenced by both population history and natural selection. The purpose of this study is to distinguish between these two evolutionary forces. We observe the simulated distribution of Tajima’s D under an equilibrium model, an exponential growth model, and a population bottleneck model. We note the probability of rejection under Tajima’s published critical values, and subsequently generate a corrected set of critical values for each demographic scenario. Utilizing these adjusted values should increase the power and reduce the chance that demography will cause the rejection of the null hypothesis of the Tajima’s D test.},
language = {en},
author = {Schmidt, Deena and Pool, John},
keywords = {⛔ No DOI found},
}
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