@article{RN197,
   author = {Schnerr, R. S. and Jansen, J. F. A. and Uludag, K. and Hofman, P. A. M. and Wildberger, J. E. and van Oostenbrugge, R. J. and Backes, W. H.},
   title = {Pulsatility of Lenticulostriate Arteries Assessed by 7 Tesla Flow MRI-Measurement, Reproducibility, and Applicability to Aging Effect},
   journal = {Front Physiol},
   volume = {8},
   pages = {961},
   note = {Schnerr, Roald S
Jansen, Jacobus F A
Uludag, Kamil
Hofman, Paul A M
Wildberger, Joachim E
van Oostenbrugge, Robert J
Backes, Walter H
eng
Switzerland
2017/12/12 06:00
Front Physiol. 2017 Nov 24;8:961. doi: 10.3389/fphys.2017.00961. eCollection 2017.},
   abstract = {Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small lenticulostriate arteries with 7 Tesla velocity-sensitive MRI. The middle cerebral artery was included as reference. Imaging was performed in five young and five old healthy volunteers. Flow was calculated by integrating time-varying velocity values over the vascular cross-section. MRI acquisitions were performed twice in each subject to determine reproducibility. From the flow waveforms, the pulsatility index and damping factor were deduced. Reproducibility values, in terms of the intraclass correlation coefficients, were found to be good to excellent. Measured pulsatility index of the lenticulostriate arteries significantly increased and damping factor significantly decreased with age. In conclusion, we demonstrate that blood flow through the lenticostriate arteries can be precisely measured using 7 Tesla MRI and reveal effects of arterial stiffness due to aging. These findings hold promise to provide relevant insights into the pathologies involving perforating cerebral arteries.},
   keywords = {cerebral blood flow
cerebrovascular aging
damping factor
flow quantification
lenticostriate artery
middle cerebral artery
pulsatility
pulsatility index},
   ISSN = {1664-042X (Print)
1664-042X (Linking)},
   DOI = {10.3389/fphys.2017.00961},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/29225580
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705621/pdf/fphys-08-00961.pdf},
   year = {2017},
   type = {Journal Article}
}

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H."],"year":2017,"bibtype":"article","biburl":"https://raw.githubusercontent.com/jansenjfa1/bibbase.github.io/master/jansenjfa.bib","bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Schnerr"],"firstnames":["R.","S."],"suffixes":[]},{"propositions":[],"lastnames":["Jansen"],"firstnames":["J.","F.","A."],"suffixes":[]},{"propositions":[],"lastnames":["Uludag"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Hofman"],"firstnames":["P.","A.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Wildberger"],"firstnames":["J.","E."],"suffixes":[]},{"propositions":["van"],"lastnames":["Oostenbrugge"],"firstnames":["R.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Backes"],"firstnames":["W.","H."],"suffixes":[]}],"title":"Pulsatility of Lenticulostriate Arteries Assessed by 7 Tesla Flow MRI-Measurement, Reproducibility, and Applicability to Aging Effect","journal":"Front Physiol","volume":"8","pages":"961","note":"Schnerr, Roald S Jansen, Jacobus F A Uludag, Kamil Hofman, Paul A M Wildberger, Joachim E van Oostenbrugge, Robert J Backes, Walter H eng Switzerland 2017/12/12 06:00 Front Physiol. 2017 Nov 24;8:961. doi: 10.3389/fphys.2017.00961. eCollection 2017.","abstract":"Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small lenticulostriate arteries with 7 Tesla velocity-sensitive MRI. The middle cerebral artery was included as reference. Imaging was performed in five young and five old healthy volunteers. Flow was calculated by integrating time-varying velocity values over the vascular cross-section. MRI acquisitions were performed twice in each subject to determine reproducibility. From the flow waveforms, the pulsatility index and damping factor were deduced. Reproducibility values, in terms of the intraclass correlation coefficients, were found to be good to excellent. Measured pulsatility index of the lenticulostriate arteries significantly increased and damping factor significantly decreased with age. In conclusion, we demonstrate that blood flow through the lenticostriate arteries can be precisely measured using 7 Tesla MRI and reveal effects of arterial stiffness due to aging. These findings hold promise to provide relevant insights into the pathologies involving perforating cerebral arteries.","keywords":"cerebral blood flow cerebrovascular aging damping factor flow quantification lenticostriate artery middle cerebral artery pulsatility pulsatility index","issn":"1664-042X (Print) 1664-042X (Linking)","doi":"10.3389/fphys.2017.00961","url":"http://www.ncbi.nlm.nih.gov/pubmed/29225580 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705621/pdf/fphys-08-00961.pdf","year":"2017","bibtex":"@article{RN197,\n author = {Schnerr, R. S. and Jansen, J. F. A. and Uludag, K. and Hofman, P. A. M. and Wildberger, J. E. and van Oostenbrugge, R. J. and Backes, W. H.},\n title = {Pulsatility of Lenticulostriate Arteries Assessed by 7 Tesla Flow MRI-Measurement, Reproducibility, and Applicability to Aging Effect},\n journal = {Front Physiol},\n volume = {8},\n pages = {961},\n note = {Schnerr, Roald S\nJansen, Jacobus F A\nUludag, Kamil\nHofman, Paul A M\nWildberger, Joachim E\nvan Oostenbrugge, Robert J\nBackes, Walter H\neng\nSwitzerland\n2017/12/12 06:00\nFront Physiol. 2017 Nov 24;8:961. doi: 10.3389/fphys.2017.00961. eCollection 2017.},\n abstract = {Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small lenticulostriate arteries with 7 Tesla velocity-sensitive MRI. The middle cerebral artery was included as reference. Imaging was performed in five young and five old healthy volunteers. Flow was calculated by integrating time-varying velocity values over the vascular cross-section. MRI acquisitions were performed twice in each subject to determine reproducibility. From the flow waveforms, the pulsatility index and damping factor were deduced. Reproducibility values, in terms of the intraclass correlation coefficients, were found to be good to excellent. Measured pulsatility index of the lenticulostriate arteries significantly increased and damping factor significantly decreased with age. In conclusion, we demonstrate that blood flow through the lenticostriate arteries can be precisely measured using 7 Tesla MRI and reveal effects of arterial stiffness due to aging. These findings hold promise to provide relevant insights into the pathologies involving perforating cerebral arteries.},\n keywords = {cerebral blood flow\ncerebrovascular aging\ndamping factor\nflow quantification\nlenticostriate artery\nmiddle cerebral artery\npulsatility\npulsatility index},\n ISSN = {1664-042X (Print)\n1664-042X (Linking)},\n DOI = {10.3389/fphys.2017.00961},\n url = {http://www.ncbi.nlm.nih.gov/pubmed/29225580\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705621/pdf/fphys-08-00961.pdf},\n year = {2017},\n type = {Journal Article}\n}\n\n","author_short":["Schnerr, R. S.","Jansen, J. F. A.","Uludag, K.","Hofman, P. A. M.","Wildberger, J. E.","van Oostenbrugge, R. J.","Backes, W. 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