The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities. Schram, M. T., Sep, S. J., van der Kallen, C. J., Dagnelie, P. C., Koster, A., Schaper, N., Henry, R. M., & Stehouwer, C. D. Eur J Epidemiol, 29(6):439-51, 2014. Schram, Miranda T Sep, Simone J S van der Kallen, Carla J Dagnelie, Pieter C Koster, Annemarie Schaper, Nicolaas Henry, Ronald M A Stehouwer, Coen D A eng Research Support, Non-U.S. Gov't Netherlands Eur J Epidemiol. 2014 Jun;29(6):439-51. doi: 10.1007/s10654-014-9889-0. Epub 2014 Apr 23.
The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities [link]Paper  doi  abstract   bibtex   
The Maastricht Study is an extensive phenotyping study that focuses on the etiology of type 2 diabetes (T2DM), its classic complications, and its emerging comorbidities. The study uses state-of-the-art imaging techniques and extensive biobanking to determine health status in a population-based cohort of 10,000 individuals that is enriched with T2DM individuals. Enrollment started in November 2010 and is anticipated to last 5-7 years. The Maastricht Study is expected to become one of the most extensive phenotyping studies in both the general population and T2DM participants world-wide. The Maastricht study will specifically focus on possible mechanisms that may explain why T2DM accelerates the development and progression of classic complications, such as cardiovascular disease, retinopathy, neuropathy and nephropathy and of emerging comorbidities, such as cognitive decline, depression, and gastrointestinal, musculoskeletal and respiratory diseases. In addition, it will also examine the association of these variables with quality of life and use of health care resources. This paper describes the rationale, overall study design, recruitment strategy and methods of basic measurements, and gives an overview of all measurements that are performed within The Maastricht Study.
@article{RN293,
   author = {Schram, M. T. and Sep, S. J. and van der Kallen, C. J. and Dagnelie, P. C. and Koster, A. and Schaper, N. and Henry, R. M. and Stehouwer, C. D.},
   title = {The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities},
   journal = {Eur J Epidemiol},
   volume = {29},
   number = {6},
   pages = {439-51},
   note = {Schram, Miranda T
Sep, Simone J S
van der Kallen, Carla J
Dagnelie, Pieter C
Koster, Annemarie
Schaper, Nicolaas
Henry, Ronald M A
Stehouwer, Coen D A
eng
Research Support, Non-U.S. Gov't
Netherlands
Eur J Epidemiol. 2014 Jun;29(6):439-51. doi: 10.1007/s10654-014-9889-0. Epub 2014 Apr 23.},
   abstract = {The Maastricht Study is an extensive phenotyping study that focuses on the etiology of type 2 diabetes (T2DM), its classic complications, and its emerging comorbidities. The study uses state-of-the-art imaging techniques and extensive biobanking to determine health status in a population-based cohort of 10,000 individuals that is enriched with T2DM individuals. Enrollment started in November 2010 and is anticipated to last 5-7 years. The Maastricht Study is expected to become one of the most extensive phenotyping studies in both the general population and T2DM participants world-wide. The Maastricht study will specifically focus on possible mechanisms that may explain why T2DM accelerates the development and progression of classic complications, such as cardiovascular disease, retinopathy, neuropathy and nephropathy and of emerging comorbidities, such as cognitive decline, depression, and gastrointestinal, musculoskeletal and respiratory diseases. In addition, it will also examine the association of these variables with quality of life and use of health care resources. This paper describes the rationale, overall study design, recruitment strategy and methods of basic measurements, and gives an overview of all measurements that are performed within The Maastricht Study.},
   keywords = {Adult
Aged
Cardiovascular Diseases/complications/epidemiology/etiology
Comorbidity
Diabetes Mellitus, Type 2/complications/*epidemiology/*etiology
Female
Humans
*Life Style
Male
Middle Aged
Netherlands/epidemiology
*Phenotype
Population Surveillance
Prospective Studies
Risk Factors
*Social Support
Socioeconomic Factors},
   ISSN = {1573-7284 (Electronic)
0393-2990 (Linking)},
   DOI = {10.1007/s10654-014-9889-0},
   url = {https://www.ncbi.nlm.nih.gov/pubmed/24756374},
   year = {2014},
   type = {Journal Article}
}

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