Why Are Computational Neuroscience and Systems Biology So Separate?. Schutter, E. D. PLOS Computational Biology, 4(5):e1000078, May, 2008. ZSCC: 0000102 Publisher: Public Library of Science
Paper doi abstract bibtex Despite similar computational approaches, there is surprisingly little interaction between the computational neuroscience and the systems biology research communities. In this review I reconstruct the history of the two disciplines and show that this may explain why they grew up apart. The separation is a pity, as both fields can learn quite a bit from each other. Several examples are given, covering sociological, software technical, and methodological aspects. Systems biology is a better organized community which is very effective at sharing resources, while computational neuroscience has more experience in multiscale modeling and the analysis of information processing by biological systems. Finally, I speculate about how the relationship between the two fields may evolve in the near future.
@article{schutter_why_2008,
title = {Why {Are} {Computational} {Neuroscience} and {Systems} {Biology} {So} {Separate}?},
volume = {4},
issn = {1553-7358},
url = {https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000078},
doi = {10.1371/journal.pcbi.1000078},
abstract = {Despite similar computational approaches, there is surprisingly little interaction between the computational neuroscience and the systems biology research communities. In this review I reconstruct the history of the two disciplines and show that this may explain why they grew up apart. The separation is a pity, as both fields can learn quite a bit from each other. Several examples are given, covering sociological, software technical, and methodological aspects. Systems biology is a better organized community which is very effective at sharing resources, while computational neuroscience has more experience in multiscale modeling and the analysis of information processing by biological systems. Finally, I speculate about how the relationship between the two fields may evolve in the near future.},
language = {en},
number = {5},
urldate = {2021-04-20},
journal = {PLOS Computational Biology},
author = {Schutter, Erik De},
month = may,
year = {2008},
note = {ZSCC: 0000102
Publisher: Public Library of Science},
keywords = {Cellular neuroscience, Computational neuroscience, Computer software, Information processing, Neural networks, Neuronal dendrites, Neurons, Systems biology},
pages = {e1000078},
}
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