Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging. Scollan, D., Holmes, A., Winslow, R., & Forder, J. j-AJP, 275:H2308–H2318, 1998.
bibtex   
@Article{RSM:Sco98,
  author =       "D.F. Scollan and A. Holmes and R. Winslow and J.
                 Forder",
  title =        "Histological validation of myocardial microstructure
                 obtained from diffusion tensor magnetic resonance
                 imaging",
  journal =      j-AJP,
  year =         "1998",
  volume =       "275",
  pages =        "H2308--H2318",
  robnote =      "Diffusion tensor magnetic resonance imaging (MRI) is a
                 possible new means of elucidating the anatomic
                 structure of the myocardium. It enjoys several
                 advantages over traditional histological approaches,
                 including the ability to rapidly measure fiber
                 organization in isolated, perfused, arrested hearts,
                 thereby avoiding fixation and sectioning of artifacts.
                 However, quantitative validation of this MRI method has
                 been lacking. Here, fiber orientations estimated in the
                 same locations in the same heart using both diffusion
                 tensor MRI and histology are compared in a total of two
                 perfused rabbit hearts. Fiber orientations were
                 statistically similar for both methods and differed on
                 average by 12 degrees at any single location. This is
                 similar to the 10 degrees uncertainty in fiber
                 orientation achieved with histology. In addition,
                 imaging studies performed in a total of seven hearts
                 support a level of organization beyond the myofiber,
                 the recently described laminar organization of the
                 ventricular myocardium. Important paper for using
                 diffusion tensor imaging to image cardiac structure",
  bibdate =      "Sun Nov 19 13:36:14 2000",
}

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