Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue. Scuotto, M, Persico, M, Bucci, M, Vellecco, V, Borbone, N, Morelli, E, Oliviero, G, Novellino, E, Piccialli, G, Cirino, G, Varra, M, Fattorusso, C, & Mayol, L Organic & biomolecular chemistry, 12(28):5235–42, June, 2014. ![Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue. [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Herein, we report optically pure modified acyclic nucleosides as ideal probes for aptamer modification. These new monomers offer unique advantages in exploring the role played in thrombin inhibition by a single residue modification at key positions of the TBA structure.
@article{Scuotto2014,
title = {Outstanding effects on antithrombin activity of modified {TBA} diastereomers containing an optically pure acyclic nucleotide analogue.},
volume = {12},
issn = {1477-0539},
url = {http://www.ncbi.nlm.nih.gov/pubmed/24920241},
doi = {10.1039/c4ob00149d},
abstract = {Herein, we report optically pure modified acyclic nucleosides as ideal probes for aptamer modification. These new monomers offer unique advantages in exploring the role played in thrombin inhibition by a single residue modification at key positions of the TBA structure.},
number = {28},
journal = {Organic \& biomolecular chemistry},
author = {Scuotto, M and Persico, M and Bucci, M and Vellecco, V and Borbone, N and Morelli, E and Oliviero, G and Novellino, E and Piccialli, G and Cirino, G and Varra, M and Fattorusso, C and Mayol, L},
month = jun,
year = {2014},
pmid = {24920241},
keywords = {\#nosource},
pages = {5235--42},
}
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