European population substructure: clustering of northern and southern populations. Seldin, M., F., Shigeta, R., Villoslada, P., Selmi, C., Tuomilehto, J., Silva, G., Belmont, J., W., Klareskog, L., & Gregersen, P., K. PLoS genetics, 2(9):e143, 9, 2006. ![European population substructure: clustering of northern and southern populations. [pdf]](https://bibbase.org/img/filetypes/pdf.svg "pdf")
Paper ![European population substructure: clustering of northern and southern populations. [link]](https://bibbase.org/img/filetypes/link.svg "link")
Website abstract bibtex Using a genome-wide single nucleotide polymorphism (SNP) panel, we observed population structure in a diverse group of Europeans and European Americans. Under a variety of conditions and tests, there is a consistent and reproducible distinction between "northern" and "southern" European population groups: most individual participants with southern European ancestry (Italian, Spanish, Portuguese, and Greek) have >85% membership in the "southern" population; and most northern, western, eastern, and central Europeans have >90% in the "northern" population group. Ashkenazi Jewish as well as Sephardic Jewish origin also showed >85% membership in the "southern" population, consistent with a later Mediterranean origin of these ethnic groups. Based on this work, we have developed a core set of informative SNP markers that can control for this partition in European population structure in a variety of clinical and genetic studies.
@article{
title = {European population substructure: clustering of northern and southern populations.},
type = {article},
year = {2006},
identifiers = {[object Object]},
keywords = {Arthritis, Rheumatoid,Arthritis, Rheumatoid: genetics,Cluster Analysis,Europe,Europe: ethnology,European Continental Ancestry Group,European Continental Ancestry Group: genetics,Gene Frequency,Genetic Markers,Genetics, Population,Humans,Jews,Jews: genetics,Lactase,Lactase: deficiency,New York,Polymorphism, Single Nucleotide,Polymorphism, Single Nucleotide: genetics,Reproducibility of Results},
pages = {e143},
volume = {2},
websites = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1564423&tool=pmcentrez&rendertype=abstract},
month = {9},
day = {15},
id = {a1cd57d8-8feb-3e70-8e33-05d94d2a8d0c},
created = {2017-06-19T13:46:16.494Z},
accessed = {2012-10-16},
file_attached = {true},
profile_id = {de68dde1-2ff3-3a4e-a214-ef424d0c7646},
group_id = {b2078731-0913-33b9-8902-a53629a24e83},
last_modified = {2017-06-19T13:46:16.740Z},
read = {false},
starred = {false},
authored = {false},
confirmed = {true},
hidden = {false},
abstract = {Using a genome-wide single nucleotide polymorphism (SNP) panel, we observed population structure in a diverse group of Europeans and European Americans. Under a variety of conditions and tests, there is a consistent and reproducible distinction between "northern" and "southern" European population groups: most individual participants with southern European ancestry (Italian, Spanish, Portuguese, and Greek) have >85% membership in the "southern" population; and most northern, western, eastern, and central Europeans have >90% in the "northern" population group. Ashkenazi Jewish as well as Sephardic Jewish origin also showed >85% membership in the "southern" population, consistent with a later Mediterranean origin of these ethnic groups. Based on this work, we have developed a core set of informative SNP markers that can control for this partition in European population structure in a variety of clinical and genetic studies.},
bibtype = {article},
author = {Seldin, Michael F and Shigeta, Russell and Villoslada, Pablo and Selmi, Carlo and Tuomilehto, Jaakko and Silva, Gabriel and Belmont, John W and Klareskog, Lars and Gregersen, Peter K},
journal = {PLoS genetics},
number = {9}
}