Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea. Serrano-Pariente, J., Plaza, V., Soriano, J. B., Mayos, M., López-Viña, A., Picado, C., Vigil, L., & CPASMA Trial Group Allergy, 72(5):802–12, 2017. doi abstract bibtex BACKGROUND: Continuous positive airway pressure (CPAP) in asthma patients with concomitant obstructive sleep apnea syndrome (OSAS) seems to have a favorable impact on asthma, but data are inconsistent due to methodological limitations of previous studies. METHODS: Prospective, multicenter study. We examined asthma outcomes after 6 months of CPAP in 99 adult asthma patients (mean age 57 years) with OSAS (respiratory disturbance index ≥20). Asthma control and quality of life were assessed with the Asthma Control Questionnaire (ACQ) and the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), respectively. Data were analyzed by intention-to-treat basis. RESULTS: The mean ± SD score of the ACQ decreased from 1.39 ± 0.91 at baseline to 1.0 ± 0.78 at 6 months (P = 0.003), the percentage of patients with uncontrolled asthma from 41.4% to 17.2% (P = 0.006), and the percentage of patients with asthma attacks in the 6 months before and after treatment from 35.4% to 17.2% (P = 0.015). The score of the mAQLQ increased from 5.12 ± 1.38 to 5.63 ± 1.17 (P = 0.009). There were also significant improvements in symptoms of gastroesophageal reflux and rhinitis, bronchial reversibility, and exhaled nitric oxide values (all P \textless 0.05). No significant changes were observed in drug therapy for asthma or their comorbidities nor in the patients' weight. CONCLUSIONS: Asthma control (both actual and future risk), quality of life, and lung function improved after starting continuous positive airway pressure in asthmatics with moderate to severe obstructive sleep apnea syndrome.
@article{serrano-pariente_asthma_2017,
title = {Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea},
volume = {72},
issn = {1398-9995},
doi = {10.1111/all.13070},
abstract = {BACKGROUND: Continuous positive airway pressure (CPAP) in asthma patients with concomitant obstructive sleep apnea syndrome (OSAS) seems to have a favorable impact on asthma, but data are inconsistent due to methodological limitations of previous studies.
METHODS: Prospective, multicenter study. We examined asthma outcomes after 6 months of CPAP in 99 adult asthma patients (mean age 57 years) with OSAS (respiratory disturbance index ≥20). Asthma control and quality of life were assessed with the Asthma Control Questionnaire (ACQ) and the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), respectively. Data were analyzed by intention-to-treat basis.
RESULTS: The mean ± SD score of the ACQ decreased from 1.39 ± 0.91 at baseline to 1.0 ± 0.78 at 6 months (P = 0.003), the percentage of patients with uncontrolled asthma from 41.4\% to 17.2\% (P = 0.006), and the percentage of patients with asthma attacks in the 6 months before and after treatment from 35.4\% to 17.2\% (P = 0.015). The score of the mAQLQ increased from 5.12 ± 1.38 to 5.63 ± 1.17 (P = 0.009). There were also significant improvements in symptoms of gastroesophageal reflux and rhinitis, bronchial reversibility, and exhaled nitric oxide values (all P {\textless} 0.05). No significant changes were observed in drug therapy for asthma or their comorbidities nor in the patients' weight.
CONCLUSIONS: Asthma control (both actual and future risk), quality of life, and lung function improved after starting continuous positive airway pressure in asthmatics with moderate to severe obstructive sleep apnea syndrome.},
language = {ENG},
number = {5},
journal = {Allergy},
author = {Serrano-Pariente, J. and Plaza, V. and Soriano, J. B. and Mayos, M. and López-Viña, A. and Picado, C. and Vigil, L. and {CPASMA Trial Group}},
year = {2017},
pmid = {27732758},
keywords = {Article, Asthma, Continuous positive airway pressure, Quality of Life, acute stroke, bronchial hyperreactivity, obstructive sleep apnea syndrome},
pages = {802--12},
}
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B.","Mayos, M.","López-Viña, A.","Picado, C.","Vigil, L.","CPASMA Trial Group"],"year":2017,"bibtype":"article","biburl":"https://bibbase.org/zotero/Bibliotecacst","bibdata":{"bibtype":"article","type":"article","title":"Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea","volume":"72","issn":"1398-9995","doi":"10.1111/all.13070","abstract":"BACKGROUND: Continuous positive airway pressure (CPAP) in asthma patients with concomitant obstructive sleep apnea syndrome (OSAS) seems to have a favorable impact on asthma, but data are inconsistent due to methodological limitations of previous studies. METHODS: Prospective, multicenter study. We examined asthma outcomes after 6 months of CPAP in 99 adult asthma patients (mean age 57 years) with OSAS (respiratory disturbance index ≥20). Asthma control and quality of life were assessed with the Asthma Control Questionnaire (ACQ) and the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), respectively. Data were analyzed by intention-to-treat basis. RESULTS: The mean ± SD score of the ACQ decreased from 1.39 ± 0.91 at baseline to 1.0 ± 0.78 at 6 months (P = 0.003), the percentage of patients with uncontrolled asthma from 41.4% to 17.2% (P = 0.006), and the percentage of patients with asthma attacks in the 6 months before and after treatment from 35.4% to 17.2% (P = 0.015). The score of the mAQLQ increased from 5.12 ± 1.38 to 5.63 ± 1.17 (P = 0.009). There were also significant improvements in symptoms of gastroesophageal reflux and rhinitis, bronchial reversibility, and exhaled nitric oxide values (all P \\textless 0.05). No significant changes were observed in drug therapy for asthma or their comorbidities nor in the patients' weight. CONCLUSIONS: Asthma control (both actual and future risk), quality of life, and lung function improved after starting continuous positive airway pressure in asthmatics with moderate to severe obstructive sleep apnea syndrome.","language":"ENG","number":"5","journal":"Allergy","author":[{"propositions":[],"lastnames":["Serrano-Pariente"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Plaza"],"firstnames":["V."],"suffixes":[]},{"propositions":[],"lastnames":["Soriano"],"firstnames":["J.","B."],"suffixes":[]},{"propositions":[],"lastnames":["Mayos"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["López-Viña"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Picado"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Vigil"],"firstnames":["L."],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["CPASMA Trial Group"],"suffixes":[]}],"year":"2017","pmid":"27732758","keywords":"Article, Asthma, Continuous positive airway pressure, Quality of Life, acute stroke, bronchial hyperreactivity, obstructive sleep apnea syndrome","pages":"802–12","bibtex":"@article{serrano-pariente_asthma_2017,\n\ttitle = {Asthma outcomes improve with continuous positive airway pressure for obstructive sleep apnea},\n\tvolume = {72},\n\tissn = {1398-9995},\n\tdoi = {10.1111/all.13070},\n\tabstract = {BACKGROUND: Continuous positive airway pressure (CPAP) in asthma patients with concomitant obstructive sleep apnea syndrome (OSAS) seems to have a favorable impact on asthma, but data are inconsistent due to methodological limitations of previous studies.\nMETHODS: Prospective, multicenter study. We examined asthma outcomes after 6 months of CPAP in 99 adult asthma patients (mean age 57 years) with OSAS (respiratory disturbance index ≥20). Asthma control and quality of life were assessed with the Asthma Control Questionnaire (ACQ) and the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), respectively. Data were analyzed by intention-to-treat basis.\nRESULTS: The mean ± SD score of the ACQ decreased from 1.39 ± 0.91 at baseline to 1.0 ± 0.78 at 6 months (P = 0.003), the percentage of patients with uncontrolled asthma from 41.4\\% to 17.2\\% (P = 0.006), and the percentage of patients with asthma attacks in the 6 months before and after treatment from 35.4\\% to 17.2\\% (P = 0.015). The score of the mAQLQ increased from 5.12 ± 1.38 to 5.63 ± 1.17 (P = 0.009). There were also significant improvements in symptoms of gastroesophageal reflux and rhinitis, bronchial reversibility, and exhaled nitric oxide values (all P {\\textless} 0.05). No significant changes were observed in drug therapy for asthma or their comorbidities nor in the patients' weight.\nCONCLUSIONS: Asthma control (both actual and future risk), quality of life, and lung function improved after starting continuous positive airway pressure in asthmatics with moderate to severe obstructive sleep apnea syndrome.},\n\tlanguage = {ENG},\n\tnumber = {5},\n\tjournal = {Allergy},\n\tauthor = {Serrano-Pariente, J. and Plaza, V. and Soriano, J. B. and Mayos, M. and López-Viña, A. and Picado, C. and Vigil, L. and {CPASMA Trial Group}},\n\tyear = {2017},\n\tpmid = {27732758},\n\tkeywords = {Article, Asthma, Continuous positive airway pressure, Quality of Life, acute stroke, bronchial hyperreactivity, obstructive sleep apnea syndrome},\n\tpages = {802--12},\n}\n\n","author_short":["Serrano-Pariente, J.","Plaza, V.","Soriano, J. 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