Trends in national incidence, lifetime prevalence and adrenaline prescribing for anaphylaxis in England. Sheikh, A., Hippisley-Cox, J., Newton, J., & Fenty, J. Journal of the Royal Society of Medicine, 101(3):139--143, March, 2008. doi abstract bibtex BACKGROUND: Analysis of primary healthcare datasets offers the possibility to increase understanding of the epidemiology of acute uncommon conditions such as anaphylaxis, but these datasets remain under-exploited. AIM: To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis in England. METHODS: QRESEARCH is one of the world's largest national aggregated health databases containing the records of over nine million patients. We extracted data on all patients with a recorded diagnosis of anaphylaxis and calculated annual age-sex standardized incidence and lifetime period prevalence rates for each year from 2001-2005. We also analysed trends in adrenaline prescribing in those with a recorded diagnosis of anaphylaxis. National population figures were used to estimate numbers of people in England that have experienced anaphylaxis at some point in their lives. RESULTS: The age-sex standardized incidence of anaphylaxis was 6.7 per 100,000 person-years in 2001 and increased by 19% to 7.9 in 2005. Lifetime age-sex standardized prevalence of a recorded diagnosis of anaphylaxis was 50.0 per 100,000 in 2001 and increased by 51% to 75.5 in 2005. Prescribing of adrenaline increased by 97% over this period. By the end of 2005 there were an estimated 37,800 people that had experienced anaphylaxis at some point in their lives. CONCLUSIONS: Recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis all showed substantial increases in recent years. An estimated 1 in 1,333 of the English population have at some point in their lives experienced anaphylaxis.
@article{sheikh_trends_2008,
title = {Trends in national incidence, lifetime prevalence and adrenaline prescribing for anaphylaxis in {England}},
volume = {101},
issn = {0141-0768},
doi = {10.1258/jrsm.2008.070306},
abstract = {BACKGROUND: Analysis of primary healthcare datasets offers the possibility to increase understanding of the epidemiology of acute uncommon conditions such as anaphylaxis, but these datasets remain under-exploited.
AIM: To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis in England.
METHODS: QRESEARCH is one of the world's largest national aggregated health databases containing the records of over nine million patients. We extracted data on all patients with a recorded diagnosis of anaphylaxis and calculated annual age-sex standardized incidence and lifetime period prevalence rates for each year from 2001-2005. We also analysed trends in adrenaline prescribing in those with a recorded diagnosis of anaphylaxis. National population figures were used to estimate numbers of people in England that have experienced anaphylaxis at some point in their lives.
RESULTS: The age-sex standardized incidence of anaphylaxis was 6.7 per 100,000 person-years in 2001 and increased by 19\% to 7.9 in 2005. Lifetime age-sex standardized prevalence of a recorded diagnosis of anaphylaxis was 50.0 per 100,000 in 2001 and increased by 51\% to 75.5 in 2005. Prescribing of adrenaline increased by 97\% over this period. By the end of 2005 there were an estimated 37,800 people that had experienced anaphylaxis at some point in their lives.
CONCLUSIONS: Recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis all showed substantial increases in recent years. An estimated 1 in 1,333 of the English population have at some point in their lives experienced anaphylaxis.},
language = {eng},
number = {3},
journal = {Journal of the Royal Society of Medicine},
author = {Sheikh, Aziz and Hippisley-Cox, Julia and Newton, John and Fenty, Justin},
month = mar,
year = {2008},
pmid = {18344471},
pmcid = {PMC2270246},
keywords = {Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Anaphylaxis, Child, Child, Preschool, England, Epinephrine, Female, Humans, Male, Middle Aged, Physician's Practice Patterns, Prevalence, Sex Distribution, incidence},
pages = {139--143}
}
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AIM: To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis in England. METHODS: QRESEARCH is one of the world's largest national aggregated health databases containing the records of over nine million patients. We extracted data on all patients with a recorded diagnosis of anaphylaxis and calculated annual age-sex standardized incidence and lifetime period prevalence rates for each year from 2001-2005. We also analysed trends in adrenaline prescribing in those with a recorded diagnosis of anaphylaxis. National population figures were used to estimate numbers of people in England that have experienced anaphylaxis at some point in their lives. RESULTS: The age-sex standardized incidence of anaphylaxis was 6.7 per 100,000 person-years in 2001 and increased by 19% to 7.9 in 2005. Lifetime age-sex standardized prevalence of a recorded diagnosis of anaphylaxis was 50.0 per 100,000 in 2001 and increased by 51% to 75.5 in 2005. Prescribing of adrenaline increased by 97% over this period. By the end of 2005 there were an estimated 37,800 people that had experienced anaphylaxis at some point in their lives. CONCLUSIONS: Recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis all showed substantial increases in recent years. An estimated 1 in 1,333 of the English population have at some point in their lives experienced anaphylaxis.","language":"eng","number":"3","journal":"Journal of the Royal Society of Medicine","author":[{"propositions":[],"lastnames":["Sheikh"],"firstnames":["Aziz"],"suffixes":[]},{"propositions":[],"lastnames":["Hippisley-Cox"],"firstnames":["Julia"],"suffixes":[]},{"propositions":[],"lastnames":["Newton"],"firstnames":["John"],"suffixes":[]},{"propositions":[],"lastnames":["Fenty"],"firstnames":["Justin"],"suffixes":[]}],"month":"March","year":"2008","pmid":"18344471","pmcid":"PMC2270246","keywords":"Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Anaphylaxis, Child, Child, Preschool, England, Epinephrine, Female, Humans, Male, Middle Aged, Physician's Practice Patterns, Prevalence, Sex Distribution, incidence","pages":"139--143","bibtex":"@article{sheikh_trends_2008,\n\ttitle = {Trends in national incidence, lifetime prevalence and adrenaline prescribing for anaphylaxis in {England}},\n\tvolume = {101},\n\tissn = {0141-0768},\n\tdoi = {10.1258/jrsm.2008.070306},\n\tabstract = {BACKGROUND: Analysis of primary healthcare datasets offers the possibility to increase understanding of the epidemiology of acute uncommon conditions such as anaphylaxis, but these datasets remain under-exploited.\nAIM: To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis in England.\nMETHODS: QRESEARCH is one of the world's largest national aggregated health databases containing the records of over nine million patients. We extracted data on all patients with a recorded diagnosis of anaphylaxis and calculated annual age-sex standardized incidence and lifetime period prevalence rates for each year from 2001-2005. We also analysed trends in adrenaline prescribing in those with a recorded diagnosis of anaphylaxis. National population figures were used to estimate numbers of people in England that have experienced anaphylaxis at some point in their lives.\nRESULTS: The age-sex standardized incidence of anaphylaxis was 6.7 per 100,000 person-years in 2001 and increased by 19\\% to 7.9 in 2005. Lifetime age-sex standardized prevalence of a recorded diagnosis of anaphylaxis was 50.0 per 100,000 in 2001 and increased by 51\\% to 75.5 in 2005. Prescribing of adrenaline increased by 97\\% over this period. By the end of 2005 there were an estimated 37,800 people that had experienced anaphylaxis at some point in their lives.\nCONCLUSIONS: Recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis all showed substantial increases in recent years. An estimated 1 in 1,333 of the English population have at some point in their lives experienced anaphylaxis.},\n\tlanguage = {eng},\n\tnumber = {3},\n\tjournal = {Journal of the Royal Society of Medicine},\n\tauthor = {Sheikh, Aziz and Hippisley-Cox, Julia and Newton, John and Fenty, Justin},\n\tmonth = mar,\n\tyear = {2008},\n\tpmid = {18344471},\n\tpmcid = {PMC2270246},\n\tkeywords = {Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Anaphylaxis, Child, Child, Preschool, England, Epinephrine, Female, Humans, Male, Middle Aged, Physician's Practice Patterns, Prevalence, Sex Distribution, incidence},\n\tpages = {139--143}\n}\n\n","author_short":["Sheikh, A.","Hippisley-Cox, J.","Newton, J.","Fenty, J."],"key":"sheikh_trends_2008","id":"sheikh_trends_2008","bibbaseid":"sheikh-hippisleycox-newton-fenty-trendsinnationalincidencelifetimeprevalenceandadrenalineprescribingforanaphylaxisinengland-2008","role":"author","urls":{},"keyword":["Adolescent","Adult","Age Distribution","Aged","Aged","80 and over","Anaphylaxis","Child","Child","Preschool","England","Epinephrine","Female","Humans","Male","Middle Aged","Physician's Practice Patterns","Prevalence","Sex Distribution","incidence"],"downloads":0},"search_terms":["trends","national","incidence","lifetime","prevalence","adrenaline","prescribing","anaphylaxis","england","sheikh","hippisley-cox","newton","fenty"],"keywords":["adolescent","adult","age distribution","aged","aged","80 and over","anaphylaxis","child","child","preschool","england","epinephrine","female","humans","male","middle aged","physician's practice patterns","prevalence","sex distribution","incidence"],"authorIDs":[],"dataSources":["FmCWXwJibZiWNzpdc"]}