@article{siedler_hospitalization_2014,
	title = {Hospitalization with varicella and shingles before and after introduction of childhood varicella vaccination in {Germany}},
	volume = {10},
	issn = {2164-5515},
	url = {https://doi.org/10.4161/hv.34426},
	doi = {10.4161/hv.34426},
	abstract = {In Germany, one dose of varicella vaccination has been recommended for children aged {\textless}24 months since 2004, and 2 doses have been recommended since 2009. Vaccination coverage (VC) is above 80\% for one dose and 60\% for 2 doses. In this study, data on varicella- and shingles-associated hospitalizations before and after vaccine introduction were assessed. Based on ICD-coded data of the main diagnosis of hospitalized cases from 1995–2012 in Germany, annual age-adjusted and age-specific hospitalization incidences (cases/100,000; HI) were calculated. HI means 1995–2003 (pre-vaccination-period) versus 2005–2012 (post-vaccination-period) were compared. Age-specific trends and annual percentage change rates (APC) were assessed by joinpoint regression. Overall age-adjusted varicella-HI decreased from 3.3/100,000 pre-vaccination to 1.9/100,000 post vaccination. The decline was greatest in regions with the highest VC. The post-vaccination decline was greatest in children aged {\textless}1, 1–4, and 5–9 y, who had APCs of –18.2,–27.2 and –15.2, respectively, and significant joinpoints. In all other age groups no post-vaccination joinpoints were detected or they did not lead to a consistent trend. Age-adjusted shingles-HI increased from 8.8/100,000 (1995) to 16.8/100,000 (2012). Shingles-HI increased in all age groups with no significant post-vaccination joinpoints, except in children {\textless}1 and 1–4 y, where APCs of –5.6 and –3.6 were detected.Varicella vaccination significantly reduced varicella-HI in children below 10 y, but was not definitely related to varicella-HI in older age groups. A consistent increase of shingles-HI began before varicella vaccination was introduced and was not affected by vaccination.},
	number = {12},
	urldate = {2022-06-16},
	journal = {Human Vaccines \& Immunotherapeutics},
	author = {Siedler, Anette and Dettmann, Marleen},
	month = dec,
	year = {2014},
	pmid = {25483695},
	note = {Publisher: Taylor \& Francis
\_eprint: https://doi.org/10.4161/hv.34426},
	pages = {3594--3600},
}

{"_id":"mAprtKPoZdKQ6a7yY","bibbaseid":"siedler-dettmann-hospitalizationwithvaricellaandshinglesbeforeandafterintroductionofchildhoodvaricellavaccinationingermany-2014","author_short":["Siedler, A.","Dettmann, M."],"bibdata":{"bibtype":"article","type":"article","title":"Hospitalization with varicella and shingles before and after introduction of childhood varicella vaccination in Germany","volume":"10","issn":"2164-5515","url":"https://doi.org/10.4161/hv.34426","doi":"10.4161/hv.34426","abstract":"In Germany, one dose of varicella vaccination has been recommended for children aged \\textless24 months since 2004, and 2 doses have been recommended since 2009. Vaccination coverage (VC) is above 80% for one dose and 60% for 2 doses. In this study, data on varicella- and shingles-associated hospitalizations before and after vaccine introduction were assessed. Based on ICD-coded data of the main diagnosis of hospitalized cases from 1995–2012 in Germany, annual age-adjusted and age-specific hospitalization incidences (cases/100,000; HI) were calculated. HI means 1995–2003 (pre-vaccination-period) versus 2005–2012 (post-vaccination-period) were compared. Age-specific trends and annual percentage change rates (APC) were assessed by joinpoint regression. Overall age-adjusted varicella-HI decreased from 3.3/100,000 pre-vaccination to 1.9/100,000 post vaccination. The decline was greatest in regions with the highest VC. The post-vaccination decline was greatest in children aged \\textless1, 1–4, and 5–9 y, who had APCs of –18.2,–27.2 and –15.2, respectively, and significant joinpoints. In all other age groups no post-vaccination joinpoints were detected or they did not lead to a consistent trend. Age-adjusted shingles-HI increased from 8.8/100,000 (1995) to 16.8/100,000 (2012). Shingles-HI increased in all age groups with no significant post-vaccination joinpoints, except in children \\textless1 and 1–4 y, where APCs of –5.6 and –3.6 were detected.Varicella vaccination significantly reduced varicella-HI in children below 10 y, but was not definitely related to varicella-HI in older age groups. A consistent increase of shingles-HI began before varicella vaccination was introduced and was not affected by vaccination.","number":"12","urldate":"2022-06-16","journal":"Human Vaccines & Immunotherapeutics","author":[{"propositions":[],"lastnames":["Siedler"],"firstnames":["Anette"],"suffixes":[]},{"propositions":[],"lastnames":["Dettmann"],"firstnames":["Marleen"],"suffixes":[]}],"month":"December","year":"2014","pmid":"25483695","note":"Publisher: Taylor & Francis _eprint: https://doi.org/10.4161/hv.34426","pages":"3594–3600","bibtex":"@article{siedler_hospitalization_2014,\n\ttitle = {Hospitalization with varicella and shingles before and after introduction of childhood varicella vaccination in {Germany}},\n\tvolume = {10},\n\tissn = {2164-5515},\n\turl = {https://doi.org/10.4161/hv.34426},\n\tdoi = {10.4161/hv.34426},\n\tabstract = {In Germany, one dose of varicella vaccination has been recommended for children aged {\\textless}24 months since 2004, and 2 doses have been recommended since 2009. Vaccination coverage (VC) is above 80\\% for one dose and 60\\% for 2 doses. In this study, data on varicella- and shingles-associated hospitalizations before and after vaccine introduction were assessed. Based on ICD-coded data of the main diagnosis of hospitalized cases from 1995–2012 in Germany, annual age-adjusted and age-specific hospitalization incidences (cases/100,000; HI) were calculated. HI means 1995–2003 (pre-vaccination-period) versus 2005–2012 (post-vaccination-period) were compared. Age-specific trends and annual percentage change rates (APC) were assessed by joinpoint regression. Overall age-adjusted varicella-HI decreased from 3.3/100,000 pre-vaccination to 1.9/100,000 post vaccination. The decline was greatest in regions with the highest VC. The post-vaccination decline was greatest in children aged {\\textless}1, 1–4, and 5–9 y, who had APCs of –18.2,–27.2 and –15.2, respectively, and significant joinpoints. In all other age groups no post-vaccination joinpoints were detected or they did not lead to a consistent trend. Age-adjusted shingles-HI increased from 8.8/100,000 (1995) to 16.8/100,000 (2012). Shingles-HI increased in all age groups with no significant post-vaccination joinpoints, except in children {\\textless}1 and 1–4 y, where APCs of –5.6 and –3.6 were detected.Varicella vaccination significantly reduced varicella-HI in children below 10 y, but was not definitely related to varicella-HI in older age groups. A consistent increase of shingles-HI began before varicella vaccination was introduced and was not affected by vaccination.},\n\tnumber = {12},\n\turldate = {2022-06-16},\n\tjournal = {Human Vaccines \\& Immunotherapeutics},\n\tauthor = {Siedler, Anette and Dettmann, Marleen},\n\tmonth = dec,\n\tyear = {2014},\n\tpmid = {25483695},\n\tnote = {Publisher: Taylor \\& Francis\n\\_eprint: https://doi.org/10.4161/hv.34426},\n\tpages = {3594--3600},\n}\n\n","author_short":["Siedler, A.","Dettmann, M."],"key":"siedler_hospitalization_2014","id":"siedler_hospitalization_2014","bibbaseid":"siedler-dettmann-hospitalizationwithvaricellaandshinglesbeforeandafterintroductionofchildhoodvaricellavaccinationingermany-2014","role":"author","urls":{"Paper":"https://doi.org/10.4161/hv.34426"},"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/robin.marlow","dataSources":["ix72eqAAMGCuupBaz"],"keywords":[],"search_terms":["hospitalization","varicella","shingles","before","introduction","childhood","varicella","vaccination","germany","siedler","dettmann"],"title":"Hospitalization with varicella and shingles before and after introduction of childhood varicella vaccination in Germany","year":2014}