@article{RN413,
   author = {Sing, C. W. and Lin, T. C. and Bartholomew, S. and Bell, J. S. and Bennett, C. and Beyene, K. and Bosco-Levy, P. and Bradbury, B. D. and Chan, A. H. Y. and Chandran, M. and Cooper, C. and de Ridder, M. and Doyon, C. Y. and Droz-Perroteau, C. and Ganesan, G. and Hartikainen, S. and Ilomaki, J. and Jeong, H. E. and Kiel, D. P. and Kubota, K. and Lai, E. C. and Lange, J. L. and Lewiecki, E. M. and Lin, J. and Liu, J. and Maskell, J. and de Abreu, M. M. and O'Kelly, J. and Ooba, N. and Pedersen, A. B. and Prats-Uribe, A. and Prieto-Alhambra, D. and Qin, S. X. and Shin, J. Y. and Sørensen, H. T. and Tan, K. B. and Thomas, T. and Tolppanen, A. M. and Verhamme, K. M. C. and Wang, G. H. and Watcharathanakij, S. and Wood, S. J. and Cheung, C. L. and Wong, I. C. K.},
   title = {Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality},
   journal = {J Bone Miner Res},
   volume = {38},
   number = {8},
   pages = {1064-1075},
   note = {1523-4681 Sing, Chor-Wing Orcid: 0000-0002-2180-3676 Lin, Tzu-Chieh Bartholomew, Sharon Bell, J Simon Bennett, Corina Beyene, Kebede Bosco-Levy, Pauline Bradbury, Brian D Chan, Amy Hai Yan Chandran, Manju Cooper, Cyrus Orcid: 0000-0003-3510-0709 de Ridder, Maria Doyon, Caroline Y Droz-Perroteau, Cécile Ganesan, Ganga Hartikainen, Sirpa Ilomaki, Jenni Jeong, Han Eol Kiel, Douglas P Orcid: 0000-0001-8474-0310 Kubota, Kiyoshi Lai, Edward Chia-Cheng Lange, Jeff L Lewiecki, E Michael Orcid: 0000-0003-2026-9587 Lin, Julian Liu, Jiannong Maskell, Joe de Abreu, Mirhelen Mendes O'Kelly, James Ooba, Nobuhiro Pedersen, Alma B Orcid: 0000-0002-3288-9401 Prats-Uribe, Albert Prieto-Alhambra, Daniel Orcid: 0000-0002-3950-6346 Qin, Simon Xiwen Shin, Ju-Young Orcid: 0000-0002-2791-1037 Sørensen, Henrik T Tan, Kelvin Bryan Thomas, Tracy Tolppanen, Anna-Maija Verhamme, Katia M C Wang, Grace Hsin-Min Watcharathanakij, Sawaeng Wood, Stephen J Cheung, Ching-Lung Orcid: 0000-0002-6233-9144 Wong, Ian C K Journal Article Research Support, Non-U.S. Gov't United States 2023/04/29 J Bone Miner Res. 2023 Aug;38(8):1064-1075. doi: 10.1002/jbmr.4821. Epub 2023 May 29.},
   abstract = {In this international study, we examined the incidence of hip fractures, postfracture treatment, and all-cause mortality following hip fractures, based on demographics, geography, and calendar year. We used patient-level healthcare data from 19 countries and regions to identify patients aged 50 years and older hospitalized with a hip fracture from 2005 to 2018. The age- and sex-standardized incidence rates of hip fractures, post-hip fracture treatment (defined as the proportion of patients receiving anti-osteoporosis medication with various mechanisms of action [bisphosphonates, denosumab, raloxifene, strontium ranelate, or teriparatide] following a hip fracture), and the all-cause mortality rates after hip fractures were estimated using a standardized protocol and common data model. The number of hip fractures in 2050 was projected based on trends in the incidence and estimated future population demographics. In total, 4,115,046 hip fractures were identified from 20 databases. The reported age- and sex-standardized incidence rates of hip fractures ranged from 95.1 (95% confidence interval [CI] 94.8-95.4) in Brazil to 315.9 (95% CI 314.0-317.7) in Denmark per 100,000 population. Incidence rates decreased over the study period in most countries; however, the estimated total annual number of hip fractures nearly doubled from 2018 to 2050. Within 1 year following a hip fracture, post-hip fracture treatment ranged from 11.5% (95% CI 11.1% to 11.9%) in Germany to 50.3% (95% CI 50.0% to 50.7%) in the United Kingdom, and all-cause mortality rates ranged from 14.4% (95% CI 14.0% to 14.8%) in Singapore to 28.3% (95% CI 28.0% to 28.6%) in the United Kingdom. Males had lower use of anti-osteoporosis medication than females, higher rates of all-cause mortality, and a larger increase in the projected number of hip fractures by 2050. Substantial variations exist in the global epidemiology of hip fractures and postfracture outcomes. Our findings inform possible actions to reduce the projected public health burden of osteoporotic fractures among the aging population. © 2023 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).},
   keywords = {Male
Female
Humans
Middle Aged
Aged
Incidence
*Hip Fractures/drug therapy/epidemiology
*Osteoporosis/drug therapy
*Osteoporotic Fractures/epidemiology
Diphosphonates/therapeutic use
Epidemiology
Fracture prevention
Hip fracture
Mortality
Osteoporosis ,
ISSN = 0884-0431 ,
DOI = 10.1002/jbmr.4821},
   year = {2023},
   type = {Journal Article}
}

{"_id":"rzdR8pqT5v8d7zheY","bibbaseid":"sing-lin-bartholomew-bell-bennett-beyene-boscolevy-bradbury-etal-globalepidemiologyofhipfracturesseculartrendsinincidenceratepostfracturetreatmentandallcausemortality-2023","author_short":["Sing, C. W.","Lin, T. C.","Bartholomew, S.","Bell, J. S.","Bennett, C.","Beyene, K.","Bosco-Levy, P.","Bradbury, B. D.","Chan, A. H. Y.","Chandran, M.","Cooper, C.","de Ridder, M.","Doyon, C. Y.","Droz-Perroteau, C.","Ganesan, G.","Hartikainen, S.","Ilomaki, J.","Jeong, H. E.","Kiel, D. P.","Kubota, K.","Lai, E. C.","Lange, J. L.","Lewiecki, E. M.","Lin, J.","Liu, J.","Maskell, J.","de Abreu, M. M.","O'Kelly, J.","Ooba, N.","Pedersen, A. B.","Prats-Uribe, A.","Prieto-Alhambra, D.","Qin, S. X.","Shin, J. Y.","Sørensen, H. T.","Tan, K. B.","Thomas, T.","Tolppanen, A. M.","Verhamme, K. M. C.","Wang, G. H.","Watcharathanakij, S.","Wood, S. J.","Cheung, C. L.","Wong, I. C. K."],"bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Sing"],"firstnames":["C.","W."],"suffixes":[]},{"propositions":[],"lastnames":["Lin"],"firstnames":["T.","C."],"suffixes":[]},{"propositions":[],"lastnames":["Bartholomew"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Bell"],"firstnames":["J.","S."],"suffixes":[]},{"propositions":[],"lastnames":["Bennett"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Beyene"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Bosco-Levy"],"firstnames":["P."],"suffixes":[]},{"propositions":[],"lastnames":["Bradbury"],"firstnames":["B.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Chan"],"firstnames":["A.","H.","Y."],"suffixes":[]},{"propositions":[],"lastnames":["Chandran"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Cooper"],"firstnames":["C."],"suffixes":[]},{"propositions":["de"],"lastnames":["Ridder"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Doyon"],"firstnames":["C.","Y."],"suffixes":[]},{"propositions":[],"lastnames":["Droz-Perroteau"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Ganesan"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Hartikainen"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Ilomaki"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Jeong"],"firstnames":["H.","E."],"suffixes":[]},{"propositions":[],"lastnames":["Kiel"],"firstnames":["D.","P."],"suffixes":[]},{"propositions":[],"lastnames":["Kubota"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Lai"],"firstnames":["E.","C."],"suffixes":[]},{"propositions":[],"lastnames":["Lange"],"firstnames":["J.","L."],"suffixes":[]},{"propositions":[],"lastnames":["Lewiecki"],"firstnames":["E.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Lin"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Liu"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Maskell"],"firstnames":["J."],"suffixes":[]},{"propositions":["de"],"lastnames":["Abreu"],"firstnames":["M.","M."],"suffixes":[]},{"propositions":[],"lastnames":["O'Kelly"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Ooba"],"firstnames":["N."],"suffixes":[]},{"propositions":[],"lastnames":["Pedersen"],"firstnames":["A.","B."],"suffixes":[]},{"propositions":[],"lastnames":["Prats-Uribe"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Prieto-Alhambra"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Qin"],"firstnames":["S.","X."],"suffixes":[]},{"propositions":[],"lastnames":["Shin"],"firstnames":["J.","Y."],"suffixes":[]},{"propositions":[],"lastnames":["Sørensen"],"firstnames":["H.","T."],"suffixes":[]},{"propositions":[],"lastnames":["Tan"],"firstnames":["K.","B."],"suffixes":[]},{"propositions":[],"lastnames":["Thomas"],"firstnames":["T."],"suffixes":[]},{"propositions":[],"lastnames":["Tolppanen"],"firstnames":["A.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Verhamme"],"firstnames":["K.","M.","C."],"suffixes":[]},{"propositions":[],"lastnames":["Wang"],"firstnames":["G.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Watcharathanakij"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Wood"],"firstnames":["S.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Cheung"],"firstnames":["C.","L."],"suffixes":[]},{"propositions":[],"lastnames":["Wong"],"firstnames":["I.","C.","K."],"suffixes":[]}],"title":"Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality","journal":"J Bone Miner Res","volume":"38","number":"8","pages":"1064-1075","note":"1523-4681 Sing, Chor-Wing Orcid: 0000-0002-2180-3676 Lin, Tzu-Chieh Bartholomew, Sharon Bell, J Simon Bennett, Corina Beyene, Kebede Bosco-Levy, Pauline Bradbury, Brian D Chan, Amy Hai Yan Chandran, Manju Cooper, Cyrus Orcid: 0000-0003-3510-0709 de Ridder, Maria Doyon, Caroline Y Droz-Perroteau, Cécile Ganesan, Ganga Hartikainen, Sirpa Ilomaki, Jenni Jeong, Han Eol Kiel, Douglas P Orcid: 0000-0001-8474-0310 Kubota, Kiyoshi Lai, Edward Chia-Cheng Lange, Jeff L Lewiecki, E Michael Orcid: 0000-0003-2026-9587 Lin, Julian Liu, Jiannong Maskell, Joe de Abreu, Mirhelen Mendes O'Kelly, James Ooba, Nobuhiro Pedersen, Alma B Orcid: 0000-0002-3288-9401 Prats-Uribe, Albert Prieto-Alhambra, Daniel Orcid: 0000-0002-3950-6346 Qin, Simon Xiwen Shin, Ju-Young Orcid: 0000-0002-2791-1037 Sørensen, Henrik T Tan, Kelvin Bryan Thomas, Tracy Tolppanen, Anna-Maija Verhamme, Katia M C Wang, Grace Hsin-Min Watcharathanakij, Sawaeng Wood, Stephen J Cheung, Ching-Lung Orcid: 0000-0002-6233-9144 Wong, Ian C K Journal Article Research Support, Non-U.S. Gov't United States 2023/04/29 J Bone Miner Res. 2023 Aug;38(8):1064-1075. doi: 10.1002/jbmr.4821. Epub 2023 May 29.","abstract":"In this international study, we examined the incidence of hip fractures, postfracture treatment, and all-cause mortality following hip fractures, based on demographics, geography, and calendar year. We used patient-level healthcare data from 19 countries and regions to identify patients aged 50 years and older hospitalized with a hip fracture from 2005 to 2018. The age- and sex-standardized incidence rates of hip fractures, post-hip fracture treatment (defined as the proportion of patients receiving anti-osteoporosis medication with various mechanisms of action [bisphosphonates, denosumab, raloxifene, strontium ranelate, or teriparatide] following a hip fracture), and the all-cause mortality rates after hip fractures were estimated using a standardized protocol and common data model. The number of hip fractures in 2050 was projected based on trends in the incidence and estimated future population demographics. In total, 4,115,046 hip fractures were identified from 20 databases. The reported age- and sex-standardized incidence rates of hip fractures ranged from 95.1 (95% confidence interval [CI] 94.8-95.4) in Brazil to 315.9 (95% CI 314.0-317.7) in Denmark per 100,000 population. Incidence rates decreased over the study period in most countries; however, the estimated total annual number of hip fractures nearly doubled from 2018 to 2050. Within 1 year following a hip fracture, post-hip fracture treatment ranged from 11.5% (95% CI 11.1% to 11.9%) in Germany to 50.3% (95% CI 50.0% to 50.7%) in the United Kingdom, and all-cause mortality rates ranged from 14.4% (95% CI 14.0% to 14.8%) in Singapore to 28.3% (95% CI 28.0% to 28.6%) in the United Kingdom. Males had lower use of anti-osteoporosis medication than females, higher rates of all-cause mortality, and a larger increase in the projected number of hip fractures by 2050. Substantial variations exist in the global epidemiology of hip fractures and postfracture outcomes. Our findings inform possible actions to reduce the projected public health burden of osteoporotic fractures among the aging population. © 2023 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).","keywords":"Male Female Humans Middle Aged Aged Incidence *Hip Fractures/drug therapy/epidemiology *Osteoporosis/drug therapy *Osteoporotic Fractures/epidemiology Diphosphonates/therapeutic use Epidemiology Fracture prevention Hip fracture Mortality Osteoporosis , ISSN = 0884-0431 , DOI = 10.1002/jbmr.4821","year":"2023","bibtex":"@article{RN413,\r\n author = {Sing, C. W. and Lin, T. C. and Bartholomew, S. and Bell, J. S. and Bennett, C. and Beyene, K. and Bosco-Levy, P. and Bradbury, B. D. and Chan, A. H. Y. and Chandran, M. and Cooper, C. and de Ridder, M. and Doyon, C. Y. and Droz-Perroteau, C. and Ganesan, G. and Hartikainen, S. and Ilomaki, J. and Jeong, H. E. and Kiel, D. P. and Kubota, K. and Lai, E. C. and Lange, J. L. and Lewiecki, E. M. and Lin, J. and Liu, J. and Maskell, J. and de Abreu, M. M. and O'Kelly, J. and Ooba, N. and Pedersen, A. B. and Prats-Uribe, A. and Prieto-Alhambra, D. and Qin, S. X. and Shin, J. Y. and Sørensen, H. T. and Tan, K. B. and Thomas, T. and Tolppanen, A. M. and Verhamme, K. M. C. and Wang, G. H. and Watcharathanakij, S. and Wood, S. J. and Cheung, C. L. and Wong, I. C. K.},\r\n title = {Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality},\r\n journal = {J Bone Miner Res},\r\n volume = {38},\r\n number = {8},\r\n pages = {1064-1075},\r\n note = {1523-4681 Sing, Chor-Wing Orcid: 0000-0002-2180-3676 Lin, Tzu-Chieh Bartholomew, Sharon Bell, J Simon Bennett, Corina Beyene, Kebede Bosco-Levy, Pauline Bradbury, Brian D Chan, Amy Hai Yan Chandran, Manju Cooper, Cyrus Orcid: 0000-0003-3510-0709 de Ridder, Maria Doyon, Caroline Y Droz-Perroteau, Cécile Ganesan, Ganga Hartikainen, Sirpa Ilomaki, Jenni Jeong, Han Eol Kiel, Douglas P Orcid: 0000-0001-8474-0310 Kubota, Kiyoshi Lai, Edward Chia-Cheng Lange, Jeff L Lewiecki, E Michael Orcid: 0000-0003-2026-9587 Lin, Julian Liu, Jiannong Maskell, Joe de Abreu, Mirhelen Mendes O'Kelly, James Ooba, Nobuhiro Pedersen, Alma B Orcid: 0000-0002-3288-9401 Prats-Uribe, Albert Prieto-Alhambra, Daniel Orcid: 0000-0002-3950-6346 Qin, Simon Xiwen Shin, Ju-Young Orcid: 0000-0002-2791-1037 Sørensen, Henrik T Tan, Kelvin Bryan Thomas, Tracy Tolppanen, Anna-Maija Verhamme, Katia M C Wang, Grace Hsin-Min Watcharathanakij, Sawaeng Wood, Stephen J Cheung, Ching-Lung Orcid: 0000-0002-6233-9144 Wong, Ian C K Journal Article Research Support, Non-U.S. Gov't United States 2023/04/29 J Bone Miner Res. 2023 Aug;38(8):1064-1075. doi: 10.1002/jbmr.4821. Epub 2023 May 29.},\r\n abstract = {In this international study, we examined the incidence of hip fractures, postfracture treatment, and all-cause mortality following hip fractures, based on demographics, geography, and calendar year. We used patient-level healthcare data from 19 countries and regions to identify patients aged 50 years and older hospitalized with a hip fracture from 2005 to 2018. The age- and sex-standardized incidence rates of hip fractures, post-hip fracture treatment (defined as the proportion of patients receiving anti-osteoporosis medication with various mechanisms of action [bisphosphonates, denosumab, raloxifene, strontium ranelate, or teriparatide] following a hip fracture), and the all-cause mortality rates after hip fractures were estimated using a standardized protocol and common data model. The number of hip fractures in 2050 was projected based on trends in the incidence and estimated future population demographics. In total, 4,115,046 hip fractures were identified from 20 databases. The reported age- and sex-standardized incidence rates of hip fractures ranged from 95.1 (95% confidence interval [CI] 94.8-95.4) in Brazil to 315.9 (95% CI 314.0-317.7) in Denmark per 100,000 population. Incidence rates decreased over the study period in most countries; however, the estimated total annual number of hip fractures nearly doubled from 2018 to 2050. Within 1 year following a hip fracture, post-hip fracture treatment ranged from 11.5% (95% CI 11.1% to 11.9%) in Germany to 50.3% (95% CI 50.0% to 50.7%) in the United Kingdom, and all-cause mortality rates ranged from 14.4% (95% CI 14.0% to 14.8%) in Singapore to 28.3% (95% CI 28.0% to 28.6%) in the United Kingdom. Males had lower use of anti-osteoporosis medication than females, higher rates of all-cause mortality, and a larger increase in the projected number of hip fractures by 2050. Substantial variations exist in the global epidemiology of hip fractures and postfracture outcomes. Our findings inform possible actions to reduce the projected public health burden of osteoporotic fractures among the aging population. © 2023 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).},\r\n keywords = {Male\r\nFemale\r\nHumans\r\nMiddle Aged\r\nAged\r\nIncidence\r\n*Hip Fractures/drug therapy/epidemiology\r\n*Osteoporosis/drug therapy\r\n*Osteoporotic Fractures/epidemiology\r\nDiphosphonates/therapeutic use\r\nEpidemiology\r\nFracture prevention\r\nHip fracture\r\nMortality\r\nOsteoporosis ,\r\nISSN = 0884-0431 ,\r\nDOI = 10.1002/jbmr.4821},\r\n year = {2023},\r\n type = {Journal Article}\r\n}\r\n\r\n","author_short":["Sing, C. W.","Lin, T. C.","Bartholomew, S.","Bell, J. S.","Bennett, C.","Beyene, K.","Bosco-Levy, P.","Bradbury, B. D.","Chan, A. H. Y.","Chandran, M.","Cooper, C.","de Ridder, M.","Doyon, C. Y.","Droz-Perroteau, C.","Ganesan, G.","Hartikainen, S.","Ilomaki, J.","Jeong, H. E.","Kiel, D. P.","Kubota, K.","Lai, E. C.","Lange, J. L.","Lewiecki, E. M.","Lin, J.","Liu, J.","Maskell, J.","de Abreu, M. M.","O'Kelly, J.","Ooba, N.","Pedersen, A. B.","Prats-Uribe, A.","Prieto-Alhambra, D.","Qin, S. X.","Shin, J. Y.","Sørensen, H. T.","Tan, K. B.","Thomas, T.","Tolppanen, A. M.","Verhamme, K. M. C.","Wang, G. H.","Watcharathanakij, S.","Wood, S. J.","Cheung, C. L.","Wong, I. C. K."],"bibbaseid":"sing-lin-bartholomew-bell-bennett-beyene-boscolevy-bradbury-etal-globalepidemiologyofhipfracturesseculartrendsinincidenceratepostfracturetreatmentandallcausemortality-2023","role":"author","urls":{},"keyword":["Male Female Humans Middle Aged Aged Incidence *Hip Fractures/drug therapy/epidemiology *Osteoporosis/drug therapy *Osteoporotic Fractures/epidemiology Diphosphonates/therapeutic use Epidemiology Fracture prevention Hip fracture Mortality Osteoporosis","ISSN = 0884-0431","DOI = 10.1002/jbmr.4821"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/f/Y3pdXAEbo8qQHfE5w/IPCI Publications update 2026.bib","dataSources":["PJSqX8FMpCPRdw3CQ","qLDnCcKM9omXNrRY8","TB9sD3avjy7bNxfgS","vDmJPYmHEKAT3tMNL","PcZMFHooKwpboi2he"],"keywords":["male female humans middle aged aged incidence *hip fractures/drug therapy/epidemiology *osteoporosis/drug therapy *osteoporotic fractures/epidemiology diphosphonates/therapeutic use epidemiology fracture prevention hip fracture mortality osteoporosis","issn = 0884-0431","doi = 10.1002/jbmr.4821"],"search_terms":["global","epidemiology","hip","fractures","secular","trends","incidence","rate","post","fracture","treatment","cause","mortality","sing","lin","bartholomew","bell","bennett","beyene","bosco-levy","bradbury","chan","chandran","cooper","de ridder","doyon","droz-perroteau","ganesan","hartikainen","ilomaki","jeong","kiel","kubota","lai","lange","lewiecki","lin","liu","maskell","de abreu","o'kelly","ooba","pedersen","prats-uribe","prieto-alhambra","qin","shin","sørensen","tan","thomas","tolppanen","verhamme","wang","watcharathanakij","wood","cheung","wong"],"title":"Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality","year":2023}