Bioremediation: environmental clean-up through pathway engineering. Singh, S., Kang, S. H., Mulchandani, A., & Chen, W. Current Opinion in Biotechnology, 19(5):437--444, October, 2008.
Bioremediation: environmental clean-up through pathway engineering [link]Paper  doi  abstract   bibtex   
Given the immense risk posed by widespread environmental pollution by inorganic and organic chemicals, novel methods of decontamination and clean-up are required. Owing to the relatively high cost and the non-specificity of conventional techniques, bioremediation is a promising alternative technology for pollutant clean-up. Advances in bioremediation harness molecular, genetic, microbiology, and protein engineering tools and rely on identification of novel metal-sequestering peptides, rational and irrational pathway engineering, and enzyme design. Recent advances have been made for enhanced inorganic chemical remediation and organic chemical degradation using various pathway-engineering approaches and these are discussed in this review.
@article{singh_bioremediation:_2008,
	title = {Bioremediation: environmental clean-up through pathway engineering},
	volume = {19},
	issn = {0958-1669},
	shorttitle = {Bioremediation},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/18760355},
	doi = {10.1016/j.copbio.2008.07.012},
	abstract = {Given the immense risk posed by widespread environmental pollution by inorganic and organic chemicals, novel methods of decontamination and clean-up are required. Owing to the relatively high cost and the non-specificity of conventional techniques, bioremediation is a promising alternative technology for pollutant clean-up. Advances in bioremediation harness molecular, genetic, microbiology, and protein engineering tools and rely on identification of novel metal-sequestering peptides, rational and irrational pathway engineering, and enzyme design. Recent advances have been made for enhanced inorganic chemical remediation and organic chemical degradation using various pathway-engineering approaches and these are discussed in this review.},
	number = {5},
	urldate = {2009-11-15TZ},
	journal = {Current Opinion in Biotechnology},
	author = {Singh, Shailendra and Kang, Seung Hyun and Mulchandani, Ashok and Chen, Wilfred},
	month = oct,
	year = {2008},
	pmid = {18760355},
	keywords = {Biodegradation, Environmental, Biotechnology, Environmental Pollution, Escherichia coli, Forecasting, Genetic Engineering, Metabolomics, Signal Transduction},
	pages = {437--444}
}

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