Effects and mechanisms of medicinal plants on dopamine reward system to reduce complications of substance abuse: A systematic review Effects and mechanisms of medicinal plants on dopamine reward system to reduce complications of substance abuse: A sys- te. Solati, K., Asadi-Samani, M., Heidari-Soureshjani, S., & Pocock, L. WORLD FAMILY MEDICINE/MIDDLE EAST JOURNAL OF FAMILY MEDICINE World Family Medicine. WORLD FAMILY MEDICINE/MIDDLE EAST JOURNAL OF FAMILY MEDICINE, 1(10):202-207, 2017.
Effects and mechanisms of medicinal plants on dopamine reward system to reduce complications of substance abuse: A systematic review Effects and mechanisms of medicinal plants on dopamine reward system to reduce complications of substance abuse: A sys- te [pdf]Website  abstract   bibtex   
Substance abuse is one of the problems that many countries are currently dealing with and it imposes several complications on our communities. The dopamine reward system is one of the regions of the brain that plays important roles in the pleasure and persistence of addiction. This review was con-ducted to investigate the effects and action mecha-nisms of medicinal plants on the dopaminergic review system in preventing substance abuse. The key words " dopamine* " in combination with " substance abuse " , " drug abuse " , " addiction " or " medicinal plant " , " herb* " , and " phyto* " were used to retrieve relevant publications indexed in the Institute for Scientific Information (ISI) and PubMed using the EndNote software. After examining the studies, we includ-ed 23 of them in final analysis. Medicinal plants and their derivatives can exhibit anti-addiction ef-fects in substance use disorders mainly through influencing dopamine receptors (D1 and D2). They can also serve as appropriate alternatives to drugs and to help treat relapse due to stimulating the dopamine reward system. Because substance abuse is multifactorial, it should be taken into account that phytotherapy alone cannot be effective in treating it but instead a combination of different therapies should be adopted to fight it.

Downloads: 0