Effects of an alveolar recruitment manoeuvre guided by lung ultrasound on anaesthesia-induced atelectasis in infants: a randomised, controlled trial. Song I.-K., Kim E.-H., Lee J.-H., Ro S., Kim H.-S., & Kim J.-T. 2017. Paper abstract bibtex Atelectasis occurs in the majority of children undergoing general anaesthesia. Lung ultrasound has shown reliable sensitivity and specificity for diagnosing anaesthesia-induced atelectasis. We assessed the effects of a recruitment manoeuvre on atelectasis using lung ultrasound in infants undergoing general anaesthesia. Forty infants, randomly allocated to either a recruitment manoeuvre group or a control group, received volume-controlled ventilation with 5 cmH2O positive end-expiratory pressure. Lung ultrasound examination was performed twice in each patient, the first a minute after starting mechanical ventilation of the lungs and the second at the end of surgery. Patients in the recruitment manoeuvre group received ultrasound-guided recruitment manoeuvres after each lung ultrasound examination. The incidence of significant anaesthesia-induced atelectasis at the second lung ultrasound examination was less in the recruitment manoeuvre group compared with the control group (25% vs. 80%; p = 0.001; odds ratio (OR) 0.083; 95% confidence interval (CI): 0.019-0.370). The median (IQR [range]) lung ultrasound scores for consolidation and B-lines on the second examination were lower in the recruitment manoeuvre group compared with the control group; 6.0 (3.0-9.3 [0.0-14.0]) vs. 13.5 (11.0-16.5 [8.0-23.0]); p \textless 0.001 and 6.5 (3.0-12.0 [0.0-28.0]) vs. 15.0 (10.8-20.5 [7.0-28.0]); p \textless 0.001, respectively. The lung ultrasound scores for consolidation on the first and second examinations showed a negative correlation with age (r = -0.340, p = 0.008; r = -0.380, p = 0.003). We conclude that ultrasound-guided recruitment manoeuvres with positive end-expiratory pressure proved useful in reducing the incidence of anaesthesia-induced atelectasis in infants, although 5 cmH2O positive end-expiratory pressure alone was not sufficient to eliminate it. In addition, the younger the patient, the more susceptible they were to atelectasis. Copyright © 2016 The Association of Anaesthetists of Great Britain and Ireland
@misc{song_i.-k._effects_2017,
title = {Effects of an alveolar recruitment manoeuvre guided by lung ultrasound on anaesthesia-induced atelectasis in infants: a randomised, controlled trial},
url = {http://www.interscience.wiley.com/jpages/0003-2409},
abstract = {Atelectasis occurs in the majority of children undergoing general anaesthesia. Lung ultrasound has shown reliable sensitivity and specificity for diagnosing anaesthesia-induced atelectasis. We assessed the effects of a recruitment manoeuvre on atelectasis using lung ultrasound in infants undergoing general anaesthesia. Forty infants, randomly allocated to either a recruitment manoeuvre group or a control group, received volume-controlled ventilation with 5 cmH2O positive end-expiratory pressure. Lung ultrasound examination was performed twice in each patient, the first a minute after starting mechanical ventilation of the lungs and the second at the end of surgery. Patients in the recruitment manoeuvre group received ultrasound-guided recruitment manoeuvres after each lung ultrasound examination. The incidence of significant anaesthesia-induced atelectasis at the second lung ultrasound examination was less in the recruitment manoeuvre group compared with the control group (25\% vs. 80\%; p = 0.001; odds ratio (OR) 0.083; 95\% confidence interval (CI): 0.019-0.370). The median (IQR [range]) lung ultrasound scores for consolidation and B-lines on the second examination were lower in the recruitment manoeuvre group compared with the control group; 6.0 (3.0-9.3 [0.0-14.0]) vs. 13.5 (11.0-16.5 [8.0-23.0]); p {\textless} 0.001 and 6.5 (3.0-12.0 [0.0-28.0]) vs. 15.0 (10.8-20.5 [7.0-28.0]); p {\textless} 0.001, respectively. The lung ultrasound scores for consolidation on the first and second examinations showed a negative correlation with age (r = -0.340, p = 0.008; r = -0.380, p = 0.003). We conclude that ultrasound-guided recruitment manoeuvres with positive end-expiratory pressure proved useful in reducing the incidence of anaesthesia-induced atelectasis in infants, although 5 cmH2O positive end-expiratory pressure alone was not sufficient to eliminate it. In addition, the younger the patient, the more susceptible they were to atelectasis. Copyright © 2016 The Association of Anaesthetists of Great Britain and Ireland},
journal = {Anaesthesia},
author = {{Song I.-K.} and {Kim E.-H.} and {Lee J.-H.} and {Ro S.} and {Kim H.-S.} and {Kim J.-T.}},
year = {2017},
keywords = {*alveolar recruitment maneuver, *atelectasis, *atelectasis/pc [Prevention], *atelectasis/si [Side Effect], *atelectasis/th [Therapy], *atropine/ae [Adverse Drug Reaction], *desflurane/ae [Adverse Drug Reaction], *general anesthesia, *interventional ultrasonography, *pediatric anesthesia, *positive end expiratory pressure, *propofol/ae [Adverse Drug Reaction], *respiration control, *rocuronium/ae [Adverse Drug Reaction], *sevoflurane/ae [Adverse Drug Reaction], *ultrasound, age, anesthesia induction, article, artificial ventilation, atelectasis/si [Side Effect], clinical article, confidence interval, control group, controlled clinical trial, controlled study, elective surgery, end tidal carbon dioxide tension, female, general anesthesia, human, incidence, infant, male, minor surgery, neostigmine, newborn surgery, odds ratio, positive end expiratory pressure, randomized controlled trial, real time ultrasound scanner, real time ultrasound scanner/ct [Clinical Trial], surgery, ultrasound transducer, ultrasound transducer/ct [Clinical Trial]}
}
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Lung ultrasound has shown reliable sensitivity and specificity for diagnosing anaesthesia-induced atelectasis. We assessed the effects of a recruitment manoeuvre on atelectasis using lung ultrasound in infants undergoing general anaesthesia. Forty infants, randomly allocated to either a recruitment manoeuvre group or a control group, received volume-controlled ventilation with 5 cmH2O positive end-expiratory pressure. Lung ultrasound examination was performed twice in each patient, the first a minute after starting mechanical ventilation of the lungs and the second at the end of surgery. Patients in the recruitment manoeuvre group received ultrasound-guided recruitment manoeuvres after each lung ultrasound examination. The incidence of significant anaesthesia-induced atelectasis at the second lung ultrasound examination was less in the recruitment manoeuvre group compared with the control group (25% vs. 80%; p = 0.001; odds ratio (OR) 0.083; 95% confidence interval (CI): 0.019-0.370). The median (IQR [range]) lung ultrasound scores for consolidation and B-lines on the second examination were lower in the recruitment manoeuvre group compared with the control group; 6.0 (3.0-9.3 [0.0-14.0]) vs. 13.5 (11.0-16.5 [8.0-23.0]); p \\textless 0.001 and 6.5 (3.0-12.0 [0.0-28.0]) vs. 15.0 (10.8-20.5 [7.0-28.0]); p \\textless 0.001, respectively. The lung ultrasound scores for consolidation on the first and second examinations showed a negative correlation with age (r = -0.340, p = 0.008; r = -0.380, p = 0.003). We conclude that ultrasound-guided recruitment manoeuvres with positive end-expiratory pressure proved useful in reducing the incidence of anaesthesia-induced atelectasis in infants, although 5 cmH2O positive end-expiratory pressure alone was not sufficient to eliminate it. In addition, the younger the patient, the more susceptible they were to atelectasis. Copyright © 2016 The Association of Anaesthetists of Great Britain and Ireland","journal":"Anaesthesia","author":[{"firstnames":[],"propositions":[],"lastnames":["Song I.-K."],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["Kim E.-H."],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["Lee J.-H."],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["Ro S."],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["Kim H.-S."],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["Kim J.-T."],"suffixes":[]}],"year":"2017","keywords":"*alveolar recruitment maneuver, *atelectasis, *atelectasis/pc [Prevention], *atelectasis/si [Side Effect], *atelectasis/th [Therapy], *atropine/ae [Adverse Drug Reaction], *desflurane/ae [Adverse Drug Reaction], *general anesthesia, *interventional ultrasonography, *pediatric anesthesia, *positive end expiratory pressure, *propofol/ae [Adverse Drug Reaction], *respiration control, *rocuronium/ae [Adverse Drug Reaction], *sevoflurane/ae [Adverse Drug Reaction], *ultrasound, age, anesthesia induction, article, artificial ventilation, atelectasis/si [Side Effect], clinical article, confidence interval, control group, controlled clinical trial, controlled study, elective surgery, end tidal carbon dioxide tension, female, general anesthesia, human, incidence, infant, male, minor surgery, neostigmine, newborn surgery, odds ratio, positive end expiratory pressure, randomized controlled trial, real time ultrasound scanner, real time ultrasound scanner/ct [Clinical Trial], surgery, ultrasound transducer, ultrasound transducer/ct [Clinical Trial]","bibtex":"@misc{song_i.-k._effects_2017,\n\ttitle = {Effects of an alveolar recruitment manoeuvre guided by lung ultrasound on anaesthesia-induced atelectasis in infants: a randomised, controlled trial},\n\turl = {http://www.interscience.wiley.com/jpages/0003-2409},\n\tabstract = {Atelectasis occurs in the majority of children undergoing general anaesthesia. Lung ultrasound has shown reliable sensitivity and specificity for diagnosing anaesthesia-induced atelectasis. We assessed the effects of a recruitment manoeuvre on atelectasis using lung ultrasound in infants undergoing general anaesthesia. Forty infants, randomly allocated to either a recruitment manoeuvre group or a control group, received volume-controlled ventilation with 5 cmH2O positive end-expiratory pressure. Lung ultrasound examination was performed twice in each patient, the first a minute after starting mechanical ventilation of the lungs and the second at the end of surgery. Patients in the recruitment manoeuvre group received ultrasound-guided recruitment manoeuvres after each lung ultrasound examination. The incidence of significant anaesthesia-induced atelectasis at the second lung ultrasound examination was less in the recruitment manoeuvre group compared with the control group (25\\% vs. 80\\%; p = 0.001; odds ratio (OR) 0.083; 95\\% confidence interval (CI): 0.019-0.370). The median (IQR [range]) lung ultrasound scores for consolidation and B-lines on the second examination were lower in the recruitment manoeuvre group compared with the control group; 6.0 (3.0-9.3 [0.0-14.0]) vs. 13.5 (11.0-16.5 [8.0-23.0]); p {\\textless} 0.001 and 6.5 (3.0-12.0 [0.0-28.0]) vs. 15.0 (10.8-20.5 [7.0-28.0]); p {\\textless} 0.001, respectively. The lung ultrasound scores for consolidation on the first and second examinations showed a negative correlation with age (r = -0.340, p = 0.008; r = -0.380, p = 0.003). We conclude that ultrasound-guided recruitment manoeuvres with positive end-expiratory pressure proved useful in reducing the incidence of anaesthesia-induced atelectasis in infants, although 5 cmH2O positive end-expiratory pressure alone was not sufficient to eliminate it. In addition, the younger the patient, the more susceptible they were to atelectasis. Copyright © 2016 The Association of Anaesthetists of Great Britain and Ireland},\n\tjournal = {Anaesthesia},\n\tauthor = {{Song I.-K.} and {Kim E.-H.} and {Lee J.-H.} and {Ro S.} and {Kim H.-S.} and {Kim J.-T.}},\n\tyear = {2017},\n\tkeywords = {*alveolar recruitment maneuver, *atelectasis, *atelectasis/pc [Prevention], *atelectasis/si [Side Effect], *atelectasis/th [Therapy], *atropine/ae [Adverse Drug Reaction], *desflurane/ae [Adverse Drug Reaction], *general anesthesia, *interventional ultrasonography, *pediatric anesthesia, *positive end expiratory pressure, *propofol/ae [Adverse Drug Reaction], *respiration control, *rocuronium/ae [Adverse Drug Reaction], *sevoflurane/ae [Adverse Drug Reaction], *ultrasound, age, anesthesia induction, article, artificial ventilation, atelectasis/si [Side Effect], clinical article, confidence interval, control group, controlled clinical trial, controlled study, elective surgery, end tidal carbon dioxide tension, female, general anesthesia, human, incidence, infant, male, minor surgery, neostigmine, newborn surgery, odds ratio, positive end expiratory pressure, randomized controlled trial, real time ultrasound scanner, real time ultrasound scanner/ct [Clinical Trial], surgery, ultrasound transducer, ultrasound transducer/ct [Clinical Trial]}\n}\n\n","author_short":["Song I.-K.","Kim E.-H.","Lee J.-H.","Ro S.","Kim H.-S.","Kim J.-T."],"key":"song_i.-k._effects_2017","id":"song_i.-k._effects_2017","bibbaseid":"songik-kimeh-leejh-ros-kimhs-kimjt-effectsofanalveolarrecruitmentmanoeuvreguidedbylungultrasoundonanaesthesiainducedatelectasisininfantsarandomisedcontrolledtrial-2017","role":"author","urls":{"Paper":"http://www.interscience.wiley.com/jpages/0003-2409"},"keyword":["*alveolar recruitment maneuver","*atelectasis","*atelectasis/pc [Prevention]","*atelectasis/si [Side Effect]","*atelectasis/th [Therapy]","*atropine/ae [Adverse Drug Reaction]","*desflurane/ae [Adverse Drug Reaction]","*general anesthesia","*interventional ultrasonography","*pediatric anesthesia","*positive end expiratory pressure","*propofol/ae [Adverse Drug Reaction]","*respiration control","*rocuronium/ae [Adverse Drug Reaction]","*sevoflurane/ae [Adverse Drug Reaction]","*ultrasound","age","anesthesia induction","article","artificial ventilation","atelectasis/si [Side Effect]","clinical article","confidence interval","control group","controlled clinical trial","controlled study","elective surgery","end tidal carbon dioxide tension","female","general anesthesia","human","incidence","infant","male","minor surgery","neostigmine","newborn surgery","odds ratio","positive end expiratory pressure","randomized controlled trial","real time ultrasound scanner","real time ultrasound scanner/ct [Clinical Trial]","surgery","ultrasound transducer","ultrasound transducer/ct [Clinical Trial]"],"downloads":0,"html":""},"search_terms":["effects","alveolar","recruitment","manoeuvre","guided","lung","ultrasound","anaesthesia","induced","atelectasis","infants","randomised","controlled","trial","song i.-k.","kim e.-h.","lee j.-h.","ro s.","kim h.-s.","kim j.-t."],"keywords":["*alveolar recruitment maneuver","*atelectasis","*atelectasis/pc [prevention]","*atelectasis/si [side effect]","*atelectasis/th [therapy]","*atropine/ae [adverse drug reaction]","*desflurane/ae [adverse drug reaction]","*general anesthesia","*interventional ultrasonography","*pediatric anesthesia","*positive end expiratory pressure","*propofol/ae [adverse drug reaction]","*respiration control","*rocuronium/ae [adverse drug reaction]","*sevoflurane/ae [adverse drug reaction]","*ultrasound","age","anesthesia induction","article","artificial ventilation","atelectasis/si [side effect]","clinical article","confidence interval","control group","controlled clinical trial","controlled study","elective surgery","end tidal carbon dioxide tension","female","general anesthesia","human","incidence","infant","male","minor surgery","neostigmine","newborn surgery","odds ratio","positive end expiratory pressure","randomized controlled trial","real time ultrasound scanner","real time ultrasound scanner/ct [clinical trial]","surgery","ultrasound transducer","ultrasound transducer/ct [clinical trial]"],"authorIDs":[],"dataSources":["9LqPNaySNpNxYBFzj"]}