Deep optical imaging of tissue using the second and third near-infrared spectral windows. Sordillo, L., L., A., Pu, Y., Pratavieira, S., S., Budansky, Y., & Alfano, R., R., R. Journal of Biomedical Optics, 19(5):056004, 2014. Paper Website abstract bibtex Light at wavelengths in the near-infrared (NIR) region allows for deep penetration and minimal absorption through high scattering tissue media. NIR light has been conventionally used through the first NIR optical tissue window with wavelengths from 650 to 950 nm. Longer NIR wavelengths had been overlooked due to major water absorption peaks and a lack of NIR-CCD detectors. The second NIR spectral window from 1100 to 1350 nm and a new spectral window from 1600 to 1870 nm, known as the third NIR optical window, were investigated. Optical attenuation measurements from thin tissue slices of normal and malignant breast and prostate tissues, pig brain, and chicken tissue were obtained in the spectral range from 400 to 2500 nm. Optical images of chicken tissue overlying three black wires were also obtained using the second and third spectral windows. Due to a reduction in scattering and minimal absorption, longer attenuation lengths and clearer optical images could be seen in the second and third NIR optical windows compared to the conventional first NIR optical window. A possible fourth optical window centered at 2200 nm was noted.
@article{
title = {Deep optical imaging of tissue using the second and third near-infrared spectral windows},
type = {article},
year = {2014},
identifiers = {[object Object]},
keywords = {10,2014,4,9,Animals,Brain Chemistry,Brain Chemistry: physiology,Breast Neoplasms,Breast Neoplasms: chemistry,Breast Neoplasms: pathology,Chickens,Computer-Assisted,Female,Geometrical optics,Humans,Infrared devices,Male,Medica,Middle Aged,Near-Infrared,Near-Infrared: methods,Optical Imaging,Optical Imaging: methods,Prostatic Neoplasms,Prostatic Neoplasms: chemistry,Prostatic Neoplasms: pathology,Signal Processing,Spectroscopy,Swine,accepted for publication apr,attenuation length,breast cancer,imaging through turbid media,near-infrared imaging,near-infrared light,near-infrared therapeutic,near-infrared therapeutic window,optical mammography,paper 140143r received mar,published,revised manuscript received apr,scattering,second and third optical,second and third optical windows,turbid media,window,windows},
pages = {056004},
volume = {19},
websites = {http://www.ncbi.nlm.nih.gov/pubmed/24805808,http://dx.doi.org/10.1117/1.JBO.19.5.056004,http://biomedicaloptics.spiedigitallibrary.org/article.aspx?doi=10.1117/1.JBO.19.5.056004},
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abstract = {Light at wavelengths in the near-infrared (NIR) region allows for deep penetration and minimal absorption through high scattering tissue media. NIR light has been conventionally used through the first NIR optical tissue window with wavelengths from 650 to 950 nm. Longer NIR wavelengths had been overlooked due to major water absorption peaks and a lack of NIR-CCD detectors. The second NIR spectral window from 1100 to 1350 nm and a new spectral window from 1600 to 1870 nm, known as the third NIR optical window, were investigated. Optical attenuation measurements from thin tissue slices of normal and malignant breast and prostate tissues, pig brain, and chicken tissue were obtained in the spectral range from 400 to 2500 nm. Optical images of chicken tissue overlying three black wires were also obtained using the second and third spectral windows. Due to a reduction in scattering and minimal absorption, longer attenuation lengths and clearer optical images could be seen in the second and third NIR optical windows compared to the conventional first NIR optical window. A possible fourth optical window centered at 2200 nm was noted.},
bibtype = {article},
author = {Sordillo, L.A. Laura A. and Pu, Yang and Pratavieira, Sebastião Sebastiao and Budansky, Yury and Alfano, R.R. Robert R.},
journal = {Journal of Biomedical Optics},
number = {5}
}
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