Peptides in the Hydrozoa: are they transmitters?. Spencer, A. N. In Williams, R. B., Cornelius, P. F. S., Hughes, R. G., & Robson, E. A., editors, Coelenterate Biology: Recent Research on Cnidaria and Ctenophora, of Developments in Hydrobiology, pages 565–571. Springer Netherlands, 1991.
Paper doi abstract bibtex A family of peptides with the carboxy-terminus Arg-Phe-amide has been localized to specific subpopulations of neurons in every cnidarian species examined. These neurons are typically sensory in character or are associated with smooth muscle. Although a transmitter role for these peptides has been suggested for anthozoans at neuromuscular synapses, no such evidence is available for hydrozoans. Instead there is evidence that RF-amides can be modulators of neuronal activity which takes the form of a biphasic (inhibitory then excitatory) response in vivo, while in vitro only the inhibitory response is seen. Voltage clamp studies of identified motor neurons showed large, transitory outward currents when Pol-RF-amide peptide was applied.
@incollection{spencer_peptides_1991,
series = {Developments in {Hydrobiology}},
title = {Peptides in the {Hydrozoa}: are they transmitters?},
copyright = {©1991 Springer Science+Business Media Dordrecht},
isbn = {978-94-010-5428-7 978-94-011-3240-4},
shorttitle = {Peptides in the {Hydrozoa}},
url = {http://link.springer.com.ezproxy.library.ubc.ca/chapter/10.1007/978-94-011-3240-4_79},
abstract = {A family of peptides with the carboxy-terminus Arg-Phe-amide has been localized to specific subpopulations of neurons in every cnidarian species examined. These neurons are typically sensory in character or are associated with smooth muscle. Although a transmitter role for these peptides has been suggested for anthozoans at neuromuscular synapses, no such evidence is available for hydrozoans. Instead there is evidence that RF-amides can be modulators of neuronal activity which takes the form of a biphasic (inhibitory then excitatory) response in vivo, while in vitro only the inhibitory response is seen. Voltage clamp studies of identified motor neurons showed large, transitory outward currents when Pol-RF-amide peptide was applied.},
language = {en},
number = {66},
urldate = {2016-06-08},
booktitle = {Coelenterate {Biology}: {Recent} {Research} on {Cnidaria} and {Ctenophora}},
publisher = {Springer Netherlands},
author = {Spencer, A. N.},
editor = {Williams, R. B. and Cornelius, P. F. S. and Hughes, R. G. and Robson, E. A.},
year = {1991},
doi = {10.1007/978-94-011-3240-4_79},
keywords = {Hydrozoa},
pages = {565--571},
}
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