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@article{
 title = {Resolving isomeric peptide mixtures: a combined HPLC/ion mobility-TOFMS analysis of a 4000-component combinatorial library.},
 type = {article},
 year = {2002},
 identifiers = {[object Object]},
 keywords = {Chromatography, High Pressure Liquid,Combinatorial Chemistry Techniques,Peptide Library,Peptides,Peptides: chemistry,Peptides: isolation & purification,Spectrometry, Mass, Matrix-Assisted Laser Desorpti,Stereoisomerism},
 pages = {26-36},
 volume = {74},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/11795805},
 month = {1},
 day = {1},
 id = {62b5fa79-1bcd-3fef-9aec-45f7ef0d6dbb},
 created = {2014-05-31T04:14:15.000Z},
 file_attached = {true},
 profile_id = {9edae5ec-3a23-3830-8934-2c27bef6ccbe},
 group_id = {63e349d6-2c70-3938-9e67-2f6483f6cbab},
 last_modified = {2014-11-19T06:02:18.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 abstract = {A reversed-phase high-performance liquid chromatography (HPLC) separation approach has been combined with ion mobility/time-of-flight (TOF) mass spectrometry in order to characterize a combinatorial peptide library designed to contain 4000 peptides of the general form NH2-Xxx-Xxx-XXX-CO2H, NH2-Ala-Xxx-Xxx-Xxx-CO2H, NH2-Ser-Ala-Xxx-Xxx-Xxx-CO2H and NH2-Leu-Ser-Ala-Xxx-Xxx-Xxx-CO2H (where Xxx represents a randomization over 10 different amino acids: Ala, Arg, Asp, Glu, Gly, Leu, Lys, Phe, Ser, and Val). Addition of the gas-phase mobility separation between the HPLC separation and TOF measurement dimensions makes it possible to resolve many peptide isomers that have identical retention times (and masses).},
 bibtype = {article},
 author = {Srebalus, BarnesCatherineA and Hilderbrand, Amy E and Valentine, Stephen J and Clemmer, David E},
 journal = {Analytical chemistry},
 number = {1}
}