Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma. Srinath, A., Xie, B., Li, Y., Sone, J. Y., Romanos, S., Chen, C., Sharma, A., Polster, S., Dorrestein, P. C., Weldon, K. C., DeBiasse, D., Moore, T., Lightle, R., Koskimäki, J., Zhang, D., Stadnik, A., Piedad, K., Hagan, M., Shkoukani, A., Carrión-Penagos, J., Bi, D., Shen, L., Shenkar, R., Ji, Y., Sidebottom, A., Pamer, E., Gilbert, J. A., Kahn, M. L., D’Souza, M., Sulakhe, D., Awad, I. A., & Girard, R. Communications Medicine, 3(1):35, Nature Publishing Group, March, 2023.
Paper doi abstract bibtex Cavernous angiomas (CAs) affect 0.5% of the population, predisposing to serious neurologic sequelae from brain bleeding. A leaky gut epithelium associated with a permissive gut microbiome, was identified in patients who develop CAs, favoring lipid polysaccharide producing bacterial species. Micro-ribonucleic acids along with plasma levels of proteins reflecting angiogenesis and inflammation were also previously correlated with CA and CA with symptomatic hemorrhage.
@article{srinath_plasma_2023,
title = {Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma},
volume = {3},
copyright = {2023 The Author(s)},
issn = {2730-664X},
url = {https://www.nature.com/articles/s43856-023-00265-1},
doi = {10.1038/s43856-023-00265-1},
abstract = {Cavernous angiomas (CAs) affect 0.5\% of the population, predisposing to serious neurologic sequelae from brain bleeding. A leaky gut epithelium associated with a permissive gut microbiome, was identified in patients who develop CAs, favoring lipid polysaccharide producing bacterial species. Micro-ribonucleic acids along with plasma levels of proteins reflecting angiogenesis and inflammation were also previously correlated with CA and CA with symptomatic hemorrhage.},
language = {en},
number = {1},
urldate = {2025-12-23},
journal = {Communications Medicine},
publisher = {Nature Publishing Group},
author = {Srinath, Abhinav and Xie, Bingqing and Li, Ying and Sone, Je Yeong and Romanos, Sharbel and Chen, Chang and Sharma, Anukriti and Polster, Sean and Dorrestein, Pieter C. and Weldon, Kelly C. and DeBiasse, Dorothy and Moore, Thomas and Lightle, Rhonda and Koskimäki, Janne and Zhang, Dongdong and Stadnik, Agnieszka and Piedad, Kristina and Hagan, Matthew and Shkoukani, Abdallah and Carrión-Penagos, Julián and Bi, Dehua and Shen, Le and Shenkar, Robert and Ji, Yuan and Sidebottom, Ashley and Pamer, Eric and Gilbert, Jack A. and Kahn, Mark L. and D’Souza, Mark and Sulakhe, Dinanath and Awad, Issam A. and Girard, Romuald},
month = mar,
year = {2023},
keywords = {Diagnostic markers, Metabolomics, Stroke},
pages = {35},
}
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