Effect of sulphur crosslinking on the stability and transition of triple helical DNA. Srivastava, S., Gupta, V. D., & Singh, S. Indian journal of biochemistry & biophysics, 36(3):177–87, June, 1999.
Effect of sulphur crosslinking on the stability and transition of triple helical DNA. [link]Paper  abstract   bibtex   
In continuation to our work on order-order and order-disorder transition in triple stranded DNA when it is bounded to netropsin, we report in this communication the stabilizing/destabilizing effect of disulphide linkage on the phase dynamics of the triplex using the amended Zimm-Bragg theory. It is observed that in contrast to the sequential triplex–¿duplex –¿single strand melting of the uncrosslinked triplex, crosslinking causes the triplex state to melt directly to the single stranded state, with no apparent intermediary of a duplex state. Since there is no overall difference in the enthalpy of crosslinked and uncrosslinked triplexes, the transition is entropy driven.
@article{Srivastava1999,
	title = {Effect of sulphur crosslinking on the stability and transition of triple helical {DNA}.},
	volume = {36},
	issn = {0301-1208},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/10650716},
	abstract = {In continuation to our work on order-order and order-disorder transition in triple stranded DNA when it is bounded to netropsin, we report in this communication the stabilizing/destabilizing effect of disulphide linkage on the phase dynamics of the triplex using the amended Zimm-Bragg theory. It is observed that in contrast to the sequential triplex–¿duplex –¿single strand melting of the uncrosslinked triplex, crosslinking causes the triplex state to melt directly to the single stranded state, with no apparent intermediary of a duplex state. Since there is no overall difference in the enthalpy of crosslinked and uncrosslinked triplexes, the transition is entropy driven.},
	number = {3},
	journal = {Indian journal of biochemistry \& biophysics},
	author = {Srivastava, Seema and Gupta, Vishwambhar Dayal and Singh, Shyam},
	month = jun,
	year = {1999},
	pmid = {10650716},
	keywords = {\#nosource, Base Sequence, Cross-Linking Reagents, Cross-Linking Reagents: chemistry, DNA, DNA: chemistry, Disulfides, Disulfides: chemistry, Molecular Sequence Data, Nucleic Acid Conformation, Thermodynamics},
	pages = {177--87},
}

Downloads: 0