{"_id":"L8QysmJeEyzThQjLR","bibbaseid":"stek-shey-mnika-schutz-thienemann-wilkinson-lynen-meintjes-relationshipbetweenlta4hpromotorpolymorphismandtuberculosisassociatedimmunereconstitutioninflammatorysyndromeanditspreventionwithprednisone-2023","author_short":["Stek, C.","Shey, M.","Mnika, K.","Schutz, C.","Thienemann, F.","Wilkinson, R. J","Lynen, L.","Meintjes, G."],"bibdata":{"bibtype":"article","type":"article","abstract":"The development of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) and its prevention using prednisone may potentially be mediated by the LTA4H genotype. We assessed this hypothesis in a clinical trial evaluating prednisone to prevent TB-IRIS. We did not find an association between LTA4H genotype and TB-IRIS incidence or prednisone efficacy.","author":[{"propositions":[],"lastnames":["Stek"],"firstnames":["Cari"],"suffixes":[]},{"propositions":[],"lastnames":["Shey"],"firstnames":["Muki"],"suffixes":[]},{"propositions":[],"lastnames":["Mnika"],"firstnames":["Khuthala"],"suffixes":[]},{"propositions":[],"lastnames":["Schutz"],"firstnames":["Charlotte"],"suffixes":[]},{"propositions":[],"lastnames":["Thienemann"],"firstnames":["Friedrich"],"suffixes":[]},{"propositions":[],"lastnames":["Wilkinson"],"firstnames":["Robert","J"],"suffixes":[]},{"propositions":[],"lastnames":["Lynen"],"firstnames":["Lutgarde"],"suffixes":[]},{"propositions":[],"lastnames":["Meintjes"],"firstnames":["Graeme"],"suffixes":[]}],"doi":"10.1093/OFID/OFAD379","file":":C$\\$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Stek et al. - 2023 - Relationship between LTA4H promotor polymorphism and tuberculosis-associated immune reconstitution inflammatory syn.pdf:pdf","issn":"23288957","journal":"Open Forum Infectious Diseases","keywords":"IRIS,LTA4H genotype,OA,OA_PMC,corticosteroids,fund_ack,immune reconstitution inflammatory syndrome,original,tuberculosis","mendeley-tags":"OA,OA_PMC,fund_ack,original","month":"jul","number":"7","pages":"ofad379","pmid":"37520416","publisher":"Oxford Academic","title":"Relationship between LTA4H promotor polymorphism and tuberculosis-associated immune reconstitution inflammatory syndrome and its prevention with prednisone","url":"https://dx.doi.org/10.1093/ofid/ofad379","volume":"10","year":"2023","bibtex":"@article{Stek2023,\r\nabstract = {The development of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) and its prevention using prednisone may potentially be mediated by the LTA4H genotype. We assessed this hypothesis in a clinical trial evaluating prednisone to prevent TB-IRIS. We did not find an association between LTA4H genotype and TB-IRIS incidence or prednisone efficacy.},\r\nauthor = {Stek, Cari and Shey, Muki and Mnika, Khuthala and Schutz, Charlotte and Thienemann, Friedrich and Wilkinson, Robert J and Lynen, Lutgarde and Meintjes, Graeme},\r\ndoi = {10.1093/OFID/OFAD379},\r\nfile = {:C$\\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Stek et al. - 2023 - Relationship between LTA4H promotor polymorphism and tuberculosis-associated immune reconstitution inflammatory syn.pdf:pdf},\r\nissn = {23288957},\r\njournal = {Open Forum Infectious Diseases},\r\nkeywords = {IRIS,LTA4H genotype,OA,OA{\\_}PMC,corticosteroids,fund{\\_}ack,immune reconstitution inflammatory syndrome,original,tuberculosis},\r\nmendeley-tags = {OA,OA{\\_}PMC,fund{\\_}ack,original},\r\nmonth = {jul},\r\nnumber = {7},\r\npages = {ofad379},\r\npmid = {37520416},\r\npublisher = {Oxford Academic},\r\ntitle = {{Relationship between LTA4H promotor polymorphism and tuberculosis-associated immune reconstitution inflammatory syndrome and its prevention with prednisone}},\r\nurl = {https://dx.doi.org/10.1093/ofid/ofad379},\r\nvolume = {10},\r\nyear = {2023}\r\n}\r\n","author_short":["Stek, C.","Shey, M.","Mnika, K.","Schutz, C.","Thienemann, F.","Wilkinson, R. 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