Factors Associated with Enhanced Gross Motor Progress in Children with Cerebral Palsy: A Register-Based Study. Størvold, G. V, Jahnsen, R. B, Evensen, K. A. I, Romild, U. K, & Bratberg, G. H Physical & occupational therapy in pediatrics, 38(5):548–561, 2018.
Factors Associated with Enhanced Gross Motor Progress in Children with Cerebral Palsy: A Register-Based Study [link]Paper  doi  abstract   bibtex   
AIM: To examine associations between interventions and child characteristics; and enhanced gross motor progress in children with cerebral palsy (CP). METHODS: Prospective cohort study based on 2048 assessments of 442 children (256 boys, 186 girls) aged 2-12 years registered in the Cerebral Palsy Follow-up Program and the Cerebral Palsy Register of Norway. Gross motor progress estimates were based on repeated measures of reference percentiles for the Gross Motor Function Measure (GMFM-66) in a linear mixed model. Mean follow-up time: 2.9 years. RESULTS: Intensive training was the only intervention factor associated with enhanced gross motor progress (mean 3.3 percentiles, 95% CI: 1.0, 5.5 per period of ≥3 sessions per week and/or participation in an intensive program). Gross motor function was on average 24.2 percentiles (95% CI: 15.2, 33.2) lower in children with intellectual disability compared with others. Except for eating problems (-10.5 percentiles 95% CI: -18.5, -2.4) and ankle contractures by age (-1.9 percentiles 95% CI: -3.6, -0.2) no other factors examined were associated with long-term gross motor progress. CONCLUSIONS: Intensive training was associated with enhanced gross motor progress over an average of 2.9 years in children with CP. Intellectual disability was a strong negative prognostic factor. Preventing ankle contractures appears important for gross motor progress.
@article{storvold_factors_2018,
	title = {Factors {Associated} with {Enhanced} {Gross} {Motor} {Progress} in {Children} with {Cerebral} {Palsy}: {A} {Register}-{Based} {Study}},
	volume = {38},
	issn = {1541-3144},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/29714626},
	doi = {10.1080/01942638.2018.1462288},
	abstract = {AIM: To examine associations between interventions and child characteristics; and enhanced gross motor progress in children with cerebral palsy (CP). METHODS: Prospective cohort study based on 2048 assessments of 442 children (256 boys, 186 girls) aged 2-12 years registered in the Cerebral Palsy Follow-up Program and the Cerebral Palsy Register of Norway. Gross motor progress estimates were based on repeated measures of reference percentiles for the Gross Motor Function Measure (GMFM-66) in a linear mixed model. Mean follow-up time: 2.9 years. RESULTS: Intensive training was the only intervention factor associated with enhanced gross motor progress (mean 3.3 percentiles, 95\% CI: 1.0, 5.5 per period of ≥3 sessions per week and/or participation in an intensive program). Gross motor function was on average 24.2 percentiles (95\% CI: 15.2, 33.2) lower in children with intellectual disability compared with others. Except for eating problems (-10.5 percentiles 95\% CI: -18.5, -2.4) and ankle contractures by age (-1.9 percentiles 95\% CI: -3.6, -0.2) no other factors examined were associated with long-term gross motor progress. CONCLUSIONS: Intensive training was associated with enhanced gross motor progress over an average of 2.9 years in children with CP. Intellectual disability was a strong negative prognostic factor. Preventing ankle contractures appears important for gross motor progress.},
	language = {eng},
	number = {5},
	journal = {Physical \& occupational therapy in pediatrics},
	author = {Størvold, Gunfrid V and Jahnsen, Reidun B and Evensen, Kari Anne I and Romild, Ulla K and Bratberg, Grete H},
	year = {2018},
	keywords = {*Cerebral palsy, *GMFM-66 percentiles, *gross motor function, *intensive training, *prognosis, Cerebral Palsy/*physiopathology/rehabilitation, Child, Child Development/*physiology, Child, Preschool, Cohort Studies, Disability Evaluation, Exercise Therapy/statistics \& numerical data, Female, Follow-Up Studies, Humans, Male, Motor Skills/*physiology, Norway, Prognosis, Prospective Studies, Registries, Severity of Illness Index},
	pages = {548--561}
}

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