Racial Discrimination and Alcohol Problems: Examining Interactions with Genetic Risk and Impulsivity among African American Young Adults. Su, J., Trevino, A. D., Kuo, S. I., Aliev, F., Williams, C. D., Guy, M. C., Dick, D., Amstadter, A., Lilley, E., Gelzinis, R., Morris, A., Bountress, K., Adkins, A., Thomas, N., Neale, Z., Pedersen, K., Bannard, T., Cho, S., Barr, P., Byers, H., Berenz, E., Caraway, E., Clifford, J., Cooke, M., Do, E., Edwards, A., Goyal, N., Hack, L., Halberstadt, L., Hawn, S., Kuo, S., Lasko, E., Lent, J., Lind, M., Long, E., Martelli, A., Meyers, J., Mitchell, K., Moore, A., Moscati, A., Nasim, A., Opalesky, J., Overstreet, C., Pais, C., Raldiris, T., Salvatore, J., Savage, J., Smith, R., Sosnowski, D., Su, J., Walker, C., Walsh, M., Willoughby, T., Woodroof, M., Yan, J., Sun, C., Wormley, B., Riley, B., Aliev, F., Peterson, R., Webb, B., Dick, D. M., & The Spit for Science Working Group Journal of Youth and Adolescence, 51(8):1552–1567, August, 2022. ![Racial Discrimination and Alcohol Problems: Examining Interactions with Genetic Risk and Impulsivity among African American Young Adults [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Experiences of racial discrimination have been shown to increase risk for alcohol problems. Some individuals may be particularly vulnerable to the negative effects of racial discrimination. However, little research has examined interaction effects between racial discrimination and individual characteristics, such as genetic predispositions and personality, in relation to alcohol outcomes. This study examined whether genetic risk and dimensions of impulsivity moderate the association between racial discrimination and alcohol problems among African American young adults (n = 383, Mage = 20.65, SD = 2.28; 81% female). Participants completed online surveys and provided a saliva sample for genotyping. Results from multiple regression analyses indicated that both blatant and subtle forms of racial discrimination (i.e., experience of racist events and racial microaggressions) were associated with more alcohol problems. Racial microaggressions interacted with dimensions of impulsivity in relation to alcohol problems, such that racial microaggressions were associated with more alcohol problems when negative urgency was high or when sensation seeking was low. There was no significant interaction between alcohol use disorder genome-wide polygenic score and experience of racist events or racial microaggression in relation to alcohol problems, which may partly reflect low power due in part to limited representation of African-Americans in genetic research. The findings highlight the need to increase the representation of African Americans in genetically-informed research in order to better characterize genetic risk and understand gene-environment interaction in this understudied population, as well as the importance of examining impulsivity as a multidimensional construct that interacts with racial discrimination in relation to alcohol outcomes.
@article{su_racial_2022,
title = {Racial {Discrimination} and {Alcohol} {Problems}: {Examining} {Interactions} with {Genetic} {Risk} and {Impulsivity} among {African} {American} {Young} {Adults}},
volume = {51},
issn = {1573-6601},
shorttitle = {Racial {Discrimination} and {Alcohol} {Problems}},
url = {https://doi.org/10.1007/s10964-022-01609-1},
doi = {10.1007/s10964-022-01609-1},
abstract = {Experiences of racial discrimination have been shown to increase risk for alcohol problems. Some individuals may be particularly vulnerable to the negative effects of racial discrimination. However, little research has examined interaction effects between racial discrimination and individual characteristics, such as genetic predispositions and personality, in relation to alcohol outcomes. This study examined whether genetic risk and dimensions of impulsivity moderate the association between racial discrimination and alcohol problems among African American young adults (n = 383, Mage = 20.65, SD = 2.28; 81\% female). Participants completed online surveys and provided a saliva sample for genotyping. Results from multiple regression analyses indicated that both blatant and subtle forms of racial discrimination (i.e., experience of racist events and racial microaggressions) were associated with more alcohol problems. Racial microaggressions interacted with dimensions of impulsivity in relation to alcohol problems, such that racial microaggressions were associated with more alcohol problems when negative urgency was high or when sensation seeking was low. There was no significant interaction between alcohol use disorder genome-wide polygenic score and experience of racist events or racial microaggression in relation to alcohol problems, which may partly reflect low power due in part to limited representation of African-Americans in genetic research. The findings highlight the need to increase the representation of African Americans in genetically-informed research in order to better characterize genetic risk and understand gene-environment interaction in this understudied population, as well as the importance of examining impulsivity as a multidimensional construct that interacts with racial discrimination in relation to alcohol outcomes.},
language = {en},
number = {8},
urldate = {2025-06-11},
journal = {Journal of Youth and Adolescence},
author = {Su, Jinni and Trevino, Angel D. and Kuo, Sally I-Chun and Aliev, Fazil and Williams, Chelsea Derlan and Guy, Mignonne C. and Dick, Danielle and Amstadter, Ananda and Lilley, Emily and Gelzinis, Renolda and Morris, Anne and Bountress, Katie and Adkins, Amy and Thomas, Nathaniel and Neale, Zoe and Pedersen, Kimberly and Bannard, Thomas and Cho, Seung and Barr, Peter and Byers, Holly and Berenz, Erin and Caraway, Erin and Clifford, James and Cooke, Megan and Do, Elizabeth and Edwards, Alexis and Goyal, Neeru and Hack, Laura and Halberstadt, Lisa and Hawn, Sage and Kuo, Sally and Lasko, Emily and Lent, Jennifer and Lind, Mackenzie and Long, Elizabeth and Martelli, Alexandra and Meyers, Jacquelyn and Mitchell, Kerry and Moore, Ashlee and Moscati, Arden and Nasim, Aashir and Opalesky, Jill and Overstreet, Cassie and Pais, Christian and Raldiris, Tarah and Salvatore, Jessica and Savage, Jeanne and Smith, Rebecca and Sosnowski, David and Su, Jinni and Walker, Chloe and Walsh, Marcie and Willoughby, Teresa and Woodroof, Madison and Yan, Jia and Sun, Cuie and Wormley, Brandon and Riley, Brien and Aliev, Fazil and Peterson, Roseann and Webb, Bradley and Dick, Danielle M. and {The Spit for Science Working Group}},
month = aug,
year = {2022},
keywords = {Alcohol use, Behavioral Genetics, Black/African American, Ethnicity, Class, Gender and Crime, Genetic Interaction, Impulsivity, Polygenic risk, Race and Ethnicity, Race and Ethnicity Studies, Racial discrimination, Research on Racism, Anti-Semitism and Extremism},
pages = {1552--1567},
}
Downloads: 0
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This study examined whether genetic risk and dimensions of impulsivity moderate the association between racial discrimination and alcohol problems among African American young adults (n = 383, Mage = 20.65, SD = 2.28; 81% female). Participants completed online surveys and provided a saliva sample for genotyping. Results from multiple regression analyses indicated that both blatant and subtle forms of racial discrimination (i.e., experience of racist events and racial microaggressions) were associated with more alcohol problems. Racial microaggressions interacted with dimensions of impulsivity in relation to alcohol problems, such that racial microaggressions were associated with more alcohol problems when negative urgency was high or when sensation seeking was low. There was no significant interaction between alcohol use disorder genome-wide polygenic score and experience of racist events or racial microaggression in relation to alcohol problems, which may partly reflect low power due in part to limited representation of African-Americans in genetic research. 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Some individuals may be particularly vulnerable to the negative effects of racial discrimination. However, little research has examined interaction effects between racial discrimination and individual characteristics, such as genetic predispositions and personality, in relation to alcohol outcomes. This study examined whether genetic risk and dimensions of impulsivity moderate the association between racial discrimination and alcohol problems among African American young adults (n = 383, Mage = 20.65, SD = 2.28; 81\\% female). Participants completed online surveys and provided a saliva sample for genotyping. Results from multiple regression analyses indicated that both blatant and subtle forms of racial discrimination (i.e., experience of racist events and racial microaggressions) were associated with more alcohol problems. Racial microaggressions interacted with dimensions of impulsivity in relation to alcohol problems, such that racial microaggressions were associated with more alcohol problems when negative urgency was high or when sensation seeking was low. There was no significant interaction between alcohol use disorder genome-wide polygenic score and experience of racist events or racial microaggression in relation to alcohol problems, which may partly reflect low power due in part to limited representation of African-Americans in genetic research. The findings highlight the need to increase the representation of African Americans in genetically-informed research in order to better characterize genetic risk and understand gene-environment interaction in this understudied population, as well as the importance of examining impulsivity as a multidimensional construct that interacts with racial discrimination in relation to alcohol outcomes.},\n\tlanguage = {en},\n\tnumber = {8},\n\turldate = {2025-06-11},\n\tjournal = {Journal of Youth and Adolescence},\n\tauthor = {Su, Jinni and Trevino, Angel D. and Kuo, Sally I-Chun and Aliev, Fazil and Williams, Chelsea Derlan and Guy, Mignonne C. and Dick, Danielle and Amstadter, Ananda and Lilley, Emily and Gelzinis, Renolda and Morris, Anne and Bountress, Katie and Adkins, Amy and Thomas, Nathaniel and Neale, Zoe and Pedersen, Kimberly and Bannard, Thomas and Cho, Seung and Barr, Peter and Byers, Holly and Berenz, Erin and Caraway, Erin and Clifford, James and Cooke, Megan and Do, Elizabeth and Edwards, Alexis and Goyal, Neeru and Hack, Laura and Halberstadt, Lisa and Hawn, Sage and Kuo, Sally and Lasko, Emily and Lent, Jennifer and Lind, Mackenzie and Long, Elizabeth and Martelli, Alexandra and Meyers, Jacquelyn and Mitchell, Kerry and Moore, Ashlee and Moscati, Arden and Nasim, Aashir and Opalesky, Jill and Overstreet, Cassie and Pais, Christian and Raldiris, Tarah and Salvatore, Jessica and Savage, Jeanne and Smith, Rebecca and Sosnowski, David and Su, Jinni and Walker, Chloe and Walsh, Marcie and Willoughby, Teresa and Woodroof, Madison and Yan, Jia and Sun, Cuie and Wormley, Brandon and Riley, Brien and Aliev, Fazil and Peterson, Roseann and Webb, Bradley and Dick, Danielle M. and {The Spit for Science Working Group}},\n\tmonth = aug,\n\tyear = {2022},\n\tkeywords = {Alcohol use, Behavioral Genetics, Black/African American, Ethnicity, Class, Gender and Crime, Genetic Interaction, Impulsivity, Polygenic risk, Race and Ethnicity, Race and Ethnicity Studies, Racial discrimination, Research on Racism, Anti-Semitism and Extremism},\n\tpages = {1552--1567},\n}\n\n\n\n","author_short":["Su, J.","Trevino, A. 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