@article{takasuga_impact_2004,
	title = {Impact of fermented brown rice with {Aspergillus} oryzae ({FEBRA}) intake and concentrations of polybrominated diphenylethers ({PBDEs}) in blood of humans from {Japan}},
	volume = {57},
	issn = {0045-6535},
	url = {http://www.sciencedirect.com/science/article/pii/S0045653504006034},
	doi = {10.1016/j.chemosphere.2004.07.016},
	abstract = {The isotope dilution technique was applied for the analysis of new polybrominated diphenylethers (PBDEs) calibration standard (both labeled and non-labeled) using high-resolution gas chromatography–high-resolution mass spectrometry (HRGC–HRMS). The relative response factor (RRF) and relative standard deviation (RSD) for new calibration standard in Finnigan Thermo Electron (MAT-95XL) and Micromass (Autospec Ultima) were more or less identical with mean RRF (0.9882), RSD (0.0865) and CV\% of (8.75). The results also revealed for DeBDE-209 quantification; labeled DeBDE-209 is essential. Furthermore, we recommend on column injection technique with a thin film instead of splitless injection in order to reduce the thermal degradation of DeBDE-209 and formation of octabromodibenzofurans (OBDF). Besides, analysis of human blood (n = 156) of FEBRA-intake and non-FEBRA-intake individuals elucidated frequent detection of eighteen PBDE congeners. The average PBDE concentrations in non-FEBRA intake and FEBRA-intake humans were 6000–11 000 (mean: 8400) and 5400–15 000 (mean: 9900) respectively on pg/g fat basis. Although FEBRA-intake individuals showed slightly greater PBDEs, computer-normalized concentrations of TeBDE-47 corroborate FEBRA-intake individual from four family showed reduced concentrations. The contamination profiles of PBDEs varied in between family, gender as well as geography. International comparison with predominant PBDE congener (TeBDE-47) prevailed lower levels in Japan when compared to Korea, Germany and USA nevertheless, congener specific profiles were different which is in accordance with different technical PBDE usage in between countries.},
	number = {8},
	urldate = {2014-08-22},
	journal = {Chemosphere},
	author = {Takasuga, Takumi and Senthilkumar, Kurunthachalam and Takemori, Hiroaki and Ohi, Etsumasa and Tsuji, Hiroshi and Nagayama, Junya},
	month = nov,
	year = {2004},
	keywords = {Autospec Ultima, Calibration standard, Computer normalization, FEBRA, HRGC–HRMS, Human blood, MAT-95XL, PBDEs, RRF, RSD\%},
	pages = {795--811},
}

{"_id":"jLYDxH8nffHP42rfF","bibbaseid":"takasuga-senthilkumar-takemori-ohi-tsuji-nagayama-impactoffermentedbrownricewithaspergillusoryzaefebraintakeandconcentrationsofpolybrominateddiphenyletherspbdesinbloodofhumansfromjapan-2004","author_short":["Takasuga, T.","Senthilkumar, K.","Takemori, H.","Ohi, E.","Tsuji, H.","Nagayama, J."],"bibdata":{"bibtype":"article","type":"article","title":"Impact of fermented brown rice with Aspergillus oryzae (FEBRA) intake and concentrations of polybrominated diphenylethers (PBDEs) in blood of humans from Japan","volume":"57","issn":"0045-6535","url":"http://www.sciencedirect.com/science/article/pii/S0045653504006034","doi":"10.1016/j.chemosphere.2004.07.016","abstract":"The isotope dilution technique was applied for the analysis of new polybrominated diphenylethers (PBDEs) calibration standard (both labeled and non-labeled) using high-resolution gas chromatography–high-resolution mass spectrometry (HRGC–HRMS). The relative response factor (RRF) and relative standard deviation (RSD) for new calibration standard in Finnigan Thermo Electron (MAT-95XL) and Micromass (Autospec Ultima) were more or less identical with mean RRF (0.9882), RSD (0.0865) and CV% of (8.75). The results also revealed for DeBDE-209 quantification; labeled DeBDE-209 is essential. Furthermore, we recommend on column injection technique with a thin film instead of splitless injection in order to reduce the thermal degradation of DeBDE-209 and formation of octabromodibenzofurans (OBDF). Besides, analysis of human blood (n = 156) of FEBRA-intake and non-FEBRA-intake individuals elucidated frequent detection of eighteen PBDE congeners. The average PBDE concentrations in non-FEBRA intake and FEBRA-intake humans were 6000–11 000 (mean: 8400) and 5400–15 000 (mean: 9900) respectively on pg/g fat basis. Although FEBRA-intake individuals showed slightly greater PBDEs, computer-normalized concentrations of TeBDE-47 corroborate FEBRA-intake individual from four family showed reduced concentrations. The contamination profiles of PBDEs varied in between family, gender as well as geography. International comparison with predominant PBDE congener (TeBDE-47) prevailed lower levels in Japan when compared to Korea, Germany and USA nevertheless, congener specific profiles were different which is in accordance with different technical PBDE usage in between countries.","number":"8","urldate":"2014-08-22","journal":"Chemosphere","author":[{"propositions":[],"lastnames":["Takasuga"],"firstnames":["Takumi"],"suffixes":[]},{"propositions":[],"lastnames":["Senthilkumar"],"firstnames":["Kurunthachalam"],"suffixes":[]},{"propositions":[],"lastnames":["Takemori"],"firstnames":["Hiroaki"],"suffixes":[]},{"propositions":[],"lastnames":["Ohi"],"firstnames":["Etsumasa"],"suffixes":[]},{"propositions":[],"lastnames":["Tsuji"],"firstnames":["Hiroshi"],"suffixes":[]},{"propositions":[],"lastnames":["Nagayama"],"firstnames":["Junya"],"suffixes":[]}],"month":"November","year":"2004","keywords":"Autospec Ultima, Calibration standard, Computer normalization, FEBRA, HRGC–HRMS, Human blood, MAT-95XL, PBDEs, RRF, RSD%","pages":"795–811","bibtex":"@article{takasuga_impact_2004,\n\ttitle = {Impact of fermented brown rice with {Aspergillus} oryzae ({FEBRA}) intake and concentrations of polybrominated diphenylethers ({PBDEs}) in blood of humans from {Japan}},\n\tvolume = {57},\n\tissn = {0045-6535},\n\turl = {http://www.sciencedirect.com/science/article/pii/S0045653504006034},\n\tdoi = {10.1016/j.chemosphere.2004.07.016},\n\tabstract = {The isotope dilution technique was applied for the analysis of new polybrominated diphenylethers (PBDEs) calibration standard (both labeled and non-labeled) using high-resolution gas chromatography–high-resolution mass spectrometry (HRGC–HRMS). The relative response factor (RRF) and relative standard deviation (RSD) for new calibration standard in Finnigan Thermo Electron (MAT-95XL) and Micromass (Autospec Ultima) were more or less identical with mean RRF (0.9882), RSD (0.0865) and CV\\% of (8.75). The results also revealed for DeBDE-209 quantification; labeled DeBDE-209 is essential. Furthermore, we recommend on column injection technique with a thin film instead of splitless injection in order to reduce the thermal degradation of DeBDE-209 and formation of octabromodibenzofurans (OBDF). Besides, analysis of human blood (n = 156) of FEBRA-intake and non-FEBRA-intake individuals elucidated frequent detection of eighteen PBDE congeners. The average PBDE concentrations in non-FEBRA intake and FEBRA-intake humans were 6000–11 000 (mean: 8400) and 5400–15 000 (mean: 9900) respectively on pg/g fat basis. Although FEBRA-intake individuals showed slightly greater PBDEs, computer-normalized concentrations of TeBDE-47 corroborate FEBRA-intake individual from four family showed reduced concentrations. The contamination profiles of PBDEs varied in between family, gender as well as geography. International comparison with predominant PBDE congener (TeBDE-47) prevailed lower levels in Japan when compared to Korea, Germany and USA nevertheless, congener specific profiles were different which is in accordance with different technical PBDE usage in between countries.},\n\tnumber = {8},\n\turldate = {2014-08-22},\n\tjournal = {Chemosphere},\n\tauthor = {Takasuga, Takumi and Senthilkumar, Kurunthachalam and Takemori, Hiroaki and Ohi, Etsumasa and Tsuji, Hiroshi and Nagayama, Junya},\n\tmonth = nov,\n\tyear = {2004},\n\tkeywords = {Autospec Ultima, Calibration standard, Computer normalization, FEBRA, HRGC–HRMS, Human blood, MAT-95XL, PBDEs, RRF, RSD\\%},\n\tpages = {795--811},\n}\n\n","author_short":["Takasuga, T.","Senthilkumar, K.","Takemori, H.","Ohi, E.","Tsuji, H.","Nagayama, J."],"key":"takasuga_impact_2004","id":"takasuga_impact_2004","bibbaseid":"takasuga-senthilkumar-takemori-ohi-tsuji-nagayama-impactoffermentedbrownricewithaspergillusoryzaefebraintakeandconcentrationsofpolybrominateddiphenyletherspbdesinbloodofhumansfromjapan-2004","role":"author","urls":{"Paper":"http://www.sciencedirect.com/science/article/pii/S0045653504006034"},"keyword":["Autospec Ultima","Calibration standard","Computer normalization","FEBRA","HRGC–HRMS","Human blood","MAT-95XL","PBDEs","RRF","RSD%"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"http://bibbase.org/zotero/mdedeo","dataSources":["SSfxPwd7XbkRtnZ9f"],"keywords":["autospec ultima","calibration standard","computer normalization","febra","hrgc–hrms","human blood","mat-95xl","pbdes","rrf","rsd%"],"search_terms":["impact","fermented","brown","rice","aspergillus","oryzae","febra","intake","concentrations","polybrominated","diphenylethers","pbdes","blood","humans","japan","takasuga","senthilkumar","takemori","ohi","tsuji","nagayama"],"title":"Impact of fermented brown rice with Aspergillus oryzae (FEBRA) intake and concentrations of polybrominated diphenylethers (PBDEs) in blood of humans from Japan","year":2004}