@article{takei_immunological_2005,
	title = {Immunological {Characterization} of {Superantigen}-induced {Intrauterine} {Fetal} and {Newborn} {Death}},
	volume = {54},
	issn = {8755-8920},
	url = {http://doi.wiley.com/10.1111/j.1600-0897.2005.00305.x},
	doi = {10.1111/j.1600-0897.2005.00305.x},
	abstract = {Problem: The present study characterizes the immunological responses induced by superantigen and the underlying pathological mechanism using T-cell receptor-transgenic mice (TCR-Tg) to enable the ligand toxic shock syndrome toxin-1 (TSST-1) to induce a cytokine storm. Method of study: Three kinds of pregnant mice which could respond to TSST-1 at various levels were injected with TSST-1 on gestation day 17.5 and then the incidence of fetal/newborn death, production of cytokines including serum interleukin-2 (IL-2) and the histological status of the placenta were examined on day 18.5. Results: The incidence of fetal/newborn death and the concentrations of cytokines such as IL-2 were higher in TCR-Tg mother than those in other strains of mice. Pathological examinations revealed that the placenta was congestive and apoptotic in TCR-Tg mice. Conclusions: Superantigen injection into pregnant mice appears to increase the incidence of fetal/newborn death through an IL-2-dependent immunological pathway. © Blackwell Munksgaard, 2005.},
	number = {4},
	urldate = {2020-03-20},
	journal = {American Journal of Reproductive Immunology},
	author = {Takei, Eriko and Tamauchi, Hidekazu and Maruyama, Hiroko and Nakanishi, Kuniaki and Ishikawa, Masakazu and Unno, Nobuya and Habu, Sonoko},
	month = oct,
	year = {2005},
	note = {Publisher: John Wiley \& Sons, Ltd},
	keywords = {Fetal/newborn death, Interleukin-2, Superantigen, Toxic shock syndrome toxin-1},
	pages = {232--239},
}

{"_id":"47nmiby84u6uBgMzk","bibbaseid":"takei-tamauchi-maruyama-nakanishi-ishikawa-unno-habu-immunologicalcharacterizationofsuperantigeninducedintrauterinefetalandnewborndeath-2005","author_short":["Takei, E.","Tamauchi, H.","Maruyama, H.","Nakanishi, K.","Ishikawa, M.","Unno, N.","Habu, S."],"bibdata":{"bibtype":"article","type":"article","title":"Immunological Characterization of Superantigen-induced Intrauterine Fetal and Newborn Death","volume":"54","issn":"8755-8920","url":"http://doi.wiley.com/10.1111/j.1600-0897.2005.00305.x","doi":"10.1111/j.1600-0897.2005.00305.x","abstract":"Problem: The present study characterizes the immunological responses induced by superantigen and the underlying pathological mechanism using T-cell receptor-transgenic mice (TCR-Tg) to enable the ligand toxic shock syndrome toxin-1 (TSST-1) to induce a cytokine storm. Method of study: Three kinds of pregnant mice which could respond to TSST-1 at various levels were injected with TSST-1 on gestation day 17.5 and then the incidence of fetal/newborn death, production of cytokines including serum interleukin-2 (IL-2) and the histological status of the placenta were examined on day 18.5. Results: The incidence of fetal/newborn death and the concentrations of cytokines such as IL-2 were higher in TCR-Tg mother than those in other strains of mice. Pathological examinations revealed that the placenta was congestive and apoptotic in TCR-Tg mice. Conclusions: Superantigen injection into pregnant mice appears to increase the incidence of fetal/newborn death through an IL-2-dependent immunological pathway. © Blackwell Munksgaard, 2005.","number":"4","urldate":"2020-03-20","journal":"American Journal of Reproductive Immunology","author":[{"propositions":[],"lastnames":["Takei"],"firstnames":["Eriko"],"suffixes":[]},{"propositions":[],"lastnames":["Tamauchi"],"firstnames":["Hidekazu"],"suffixes":[]},{"propositions":[],"lastnames":["Maruyama"],"firstnames":["Hiroko"],"suffixes":[]},{"propositions":[],"lastnames":["Nakanishi"],"firstnames":["Kuniaki"],"suffixes":[]},{"propositions":[],"lastnames":["Ishikawa"],"firstnames":["Masakazu"],"suffixes":[]},{"propositions":[],"lastnames":["Unno"],"firstnames":["Nobuya"],"suffixes":[]},{"propositions":[],"lastnames":["Habu"],"firstnames":["Sonoko"],"suffixes":[]}],"month":"October","year":"2005","note":"Publisher: John Wiley & Sons, Ltd","keywords":"Fetal/newborn death, Interleukin-2, Superantigen, Toxic shock syndrome toxin-1","pages":"232–239","bibtex":"@article{takei_immunological_2005,\n\ttitle = {Immunological {Characterization} of {Superantigen}-induced {Intrauterine} {Fetal} and {Newborn} {Death}},\n\tvolume = {54},\n\tissn = {8755-8920},\n\turl = {http://doi.wiley.com/10.1111/j.1600-0897.2005.00305.x},\n\tdoi = {10.1111/j.1600-0897.2005.00305.x},\n\tabstract = {Problem: The present study characterizes the immunological responses induced by superantigen and the underlying pathological mechanism using T-cell receptor-transgenic mice (TCR-Tg) to enable the ligand toxic shock syndrome toxin-1 (TSST-1) to induce a cytokine storm. Method of study: Three kinds of pregnant mice which could respond to TSST-1 at various levels were injected with TSST-1 on gestation day 17.5 and then the incidence of fetal/newborn death, production of cytokines including serum interleukin-2 (IL-2) and the histological status of the placenta were examined on day 18.5. Results: The incidence of fetal/newborn death and the concentrations of cytokines such as IL-2 were higher in TCR-Tg mother than those in other strains of mice. Pathological examinations revealed that the placenta was congestive and apoptotic in TCR-Tg mice. Conclusions: Superantigen injection into pregnant mice appears to increase the incidence of fetal/newborn death through an IL-2-dependent immunological pathway. © Blackwell Munksgaard, 2005.},\n\tnumber = {4},\n\turldate = {2020-03-20},\n\tjournal = {American Journal of Reproductive Immunology},\n\tauthor = {Takei, Eriko and Tamauchi, Hidekazu and Maruyama, Hiroko and Nakanishi, Kuniaki and Ishikawa, Masakazu and Unno, Nobuya and Habu, Sonoko},\n\tmonth = oct,\n\tyear = {2005},\n\tnote = {Publisher: John Wiley \\& Sons, Ltd},\n\tkeywords = {Fetal/newborn death, Interleukin-2, Superantigen, Toxic shock syndrome toxin-1},\n\tpages = {232--239},\n}\n\n","author_short":["Takei, E.","Tamauchi, H.","Maruyama, H.","Nakanishi, K.","Ishikawa, M.","Unno, N.","Habu, S."],"key":"takei_immunological_2005","id":"takei_immunological_2005","bibbaseid":"takei-tamauchi-maruyama-nakanishi-ishikawa-unno-habu-immunologicalcharacterizationofsuperantigeninducedintrauterinefetalandnewborndeath-2005","role":"author","urls":{"Paper":"http://doi.wiley.com/10.1111/j.1600-0897.2005.00305.x"},"keyword":["Fetal/newborn death","Interleukin-2","Superantigen","Toxic shock syndrome toxin-1"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/asrommel","dataSources":["J8fbWsdsy3xAaB3pX"],"keywords":["fetal/newborn death","interleukin-2","superantigen","toxic shock syndrome toxin-1"],"search_terms":["immunological","characterization","superantigen","induced","intrauterine","fetal","newborn","death","takei","tamauchi","maruyama","nakanishi","ishikawa","unno","habu"],"title":"Immunological Characterization of Superantigen-induced Intrauterine Fetal and Newborn Death","year":2005}