An empirical approach for thermal stability (Tm) prediction of PNA/DNA duplexes. Takiya, T., Seto, Y., Yasuda, H., Suzuki, T., & Kawai, K. Nucleic acids symposium series (2004), January, 2004.
Paper doi abstract bibtex To predict the Tm value of PNA/DNA duplex, we performed to determine the melting temperature of several PNA oligomers. For Tm calculation model building, we searched the correlativity of measured Tm value and each base contents of PNA oligomer. Here, We propose a novel formula for thermal stability (Tm) prediction of PNA/DNA duplexes.
@article{Takiya2004,
title = {An empirical approach for thermal stability ({Tm}) prediction of {PNA}/{DNA} duplexes.},
issn = {1746-8272},
url = {http://www.ncbi.nlm.nih.gov/pubmed/17150513},
doi = {10.1093/nass/48.1.131},
abstract = {To predict the Tm value of PNA/DNA duplex, we performed to determine the melting temperature of several PNA oligomers. For Tm calculation model building, we searched the correlativity of measured Tm value and each base contents of PNA oligomer. Here, We propose a novel formula for thermal stability (Tm) prediction of PNA/DNA duplexes.},
number = {48},
journal = {Nucleic acids symposium series (2004)},
author = {Takiya, Toshiyuki and Seto, Yasuhiro and Yasuda, Hideyo and Suzuki, Tohru and Kawai, Keiichi},
month = jan,
year = {2004},
pmid = {17150513},
keywords = {\#nosource, Base Composition, DNA, DNA: chemistry, Empirical Research, Nucleic Acid Denaturation, Nucleic Acid Heteroduplexes, Nucleic Acid Heteroduplexes: chemistry, Peptide Nucleic Acids, Peptide Nucleic Acids: chemistry, Thermodynamics, Transition Temperature},
pages = {131--2},
}
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