Saturation of postsynaptic receptors after quantal release of transmitter. Tang, C. M., Margulis, M., Shi, Q. Y., & Fielding, A. Neuron, 13(6):1385-1393, 1994. abstract bibtex Miniature excitatory postsynaptic currents (mEPSCs) were elicited from small numbers of release sites after brief microperfusion of Ba2+ and K+ onto proximal dendritic processes of hippocampal neurons in culture. Temporal summation of closely timed mEPSCs deviated significantly from linearity. The number of instances of closely timed mEPSCs that were also closely matched in terms of peak amplitudes was significantly greater than that expected by chance. Amplitude pairing became statistically more significant after prolongation of mEPSC duration and inhibition of glutamate receptor desensitization with cyclothiazide. These results are best explained by postsynaptic receptors that approach saturation after quantal release of transmitter.
@article{ Tang_etal94,
author = {Tang, C. M. and Margulis, M. and Shi, Q. Y. and Fielding, A.},
title = {Saturation of postsynaptic receptors after quantal release of transmitter},
journal = {Neuron},
year = {1994},
volume = {13},
pages = {1385-1393},
number = {6},
abstract = { Miniature excitatory postsynaptic currents (mEPSCs) were elicited
from small numbers of release sites after brief microperfusion of
Ba2+ and K+ onto proximal dendritic processes of hippocampal neurons
in culture. Temporal summation of closely timed mEPSCs deviated significantly
from linearity. The number of instances of closely timed mEPSCs that
were also closely matched in terms of peak amplitudes was significantly
greater than that expected by chance. Amplitude pairing became statistically
more significant after prolongation of mEPSC duration and inhibition
of glutamate receptor desensitization with cyclothiazide. These results
are best explained by postsynaptic receptors that approach saturation
after quantal release of transmitter.},
en_number = { }
}
Downloads: 0
{"_id":"8QrEoef78AiQjXiGq","bibbaseid":"tang-margulis-shi-fielding-saturationofpostsynapticreceptorsafterquantalreleaseoftransmitter-1994","downloads":0,"creationDate":"2015-02-08T05:14:59.099Z","title":"Saturation of postsynaptic receptors after quantal release of transmitter","author_short":["Tang, C.<nbsp>M.","Margulis, M.","Shi, Q.<nbsp>Y.","Fielding, A."],"year":1994,"bibtype":"article","biburl":"http://cnslab.mb.jhu.edu/niebase.bib","bibdata":{"abstract":"Miniature excitatory postsynaptic currents (mEPSCs) were elicited from small numbers of release sites after brief microperfusion of Ba2+ and K+ onto proximal dendritic processes of hippocampal neurons in culture. Temporal summation of closely timed mEPSCs deviated significantly from linearity. The number of instances of closely timed mEPSCs that were also closely matched in terms of peak amplitudes was significantly greater than that expected by chance. Amplitude pairing became statistically more significant after prolongation of mEPSC duration and inhibition of glutamate receptor desensitization with cyclothiazide. These results are best explained by postsynaptic receptors that approach saturation after quantal release of transmitter.","author":["Tang, C. M.","Margulis, M.","Shi, Q. Y.","Fielding, A."],"author_short":["Tang, C.<nbsp>M.","Margulis, M.","Shi, Q.<nbsp>Y.","Fielding, A."],"bibtex":"@article{ Tang_etal94,\n author = {Tang, C. M. and Margulis, M. and Shi, Q. Y. and Fielding, A.},\n title = {Saturation of postsynaptic receptors after quantal release of transmitter},\n journal = {Neuron},\n year = {1994},\n volume = {13},\n pages = {1385-1393},\n number = {6},\n abstract = { Miniature excitatory postsynaptic currents (mEPSCs) were elicited\n\tfrom small numbers of release sites after brief microperfusion of\n\tBa2+ and K+ onto proximal dendritic processes of hippocampal neurons\n\tin culture. Temporal summation of closely timed mEPSCs deviated significantly\n\tfrom linearity. The number of instances of closely timed mEPSCs that\n\twere also closely matched in terms of peak amplitudes was significantly\n\tgreater than that expected by chance. Amplitude pairing became statistically\n\tmore significant after prolongation of mEPSC duration and inhibition\n\tof glutamate receptor desensitization with cyclothiazide. These results\n\tare best explained by postsynaptic receptors that approach saturation\n\tafter quantal release of transmitter.},\n en_number = { }\n}","bibtype":"article","en_number":"","id":"Tang_etal94","journal":"Neuron","key":"Tang_etal94","number":"6","pages":"1385-1393","title":"Saturation of postsynaptic receptors after quantal release of transmitter","type":"article","volume":"13","year":"1994","bibbaseid":"tang-margulis-shi-fielding-saturationofpostsynapticreceptorsafterquantalreleaseoftransmitter-1994","role":"author","urls":{},"downloads":0},"search_terms":["saturation","postsynaptic","receptors","quantal","release","transmitter","tang","margulis","shi","fielding"],"keywords":[],"authorIDs":[],"dataSources":["ErLXoH8mqSjESnrN5"]}