A Molecular Take on Malignant Rhabdoid Tumors. Tang, M. & Verhaak, R. G. W. Trends Cancer, 2(5):217-218, 2016. 2405-8025 Tang, Ming Verhaak, Roel G W Journal Article United States 2016/05/01 Trends Cancer. 2016 May;2(5):217-218. doi: 10.1016/j.trecan.2016.04.003. Epub 2016 Apr 28.doi abstract bibtex The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.
@article{RN6133,
author = {Tang, M. and Verhaak, R. G. W.},
title = {A Molecular Take on Malignant Rhabdoid Tumors},
journal = {Trends Cancer},
volume = {2},
number = {5},
pages = {217-218},
note = {2405-8025
Tang, Ming
Verhaak, Roel G W
Journal Article
United States
2016/05/01
Trends Cancer. 2016 May;2(5):217-218. doi: 10.1016/j.trecan.2016.04.003. Epub 2016 Apr 28.},
abstract = {The molecular basis for the clinical heterogeneity observed in patients with malignant rhabdoid tumors is unknown. Recently, two reports revealed molecular intertumor heterogeneity in teratoid/rhabdoid tumors (ATRTs) and extra-cranial MRTs (ecMRTs) using genomic, transcriptomic, and epigenomic profiling. Distinct molecular subgroups were identified and new therapeutic targets were revealed.},
keywords = {Genetic Heterogeneity
Humans
Rhabdoid Tumor/*genetics
malignant rhabdoid tumors
molecular analysis
pediatric cancer
sequencing},
ISSN = {2405-8025},
DOI = {10.1016/j.trecan.2016.04.003},
year = {2016},
type = {Journal Article}
}
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