Including Walnuts in a Low-Fat/Modified-Fat Diet Improves HDL Cholesterol-to-Total Cholesterol Ratios in Patients with Type 2 Diabetes. Tapsell, L. C., Gillen, L. J., Patch, C. S., Batterham, M., Owen, A., Baré, M., & Kennedy, M. 27(12):2777–2783.
Including Walnuts in a Low-Fat/Modified-Fat Diet Improves HDL Cholesterol-to-Total Cholesterol Ratios in Patients with Type 2 Diabetes [link]Paper  doi  abstract   bibtex   
[OBJECTIVE] – The aim of this study was to examine the effect of a moderate-fat diet inclusive of walnuts on blood lipid profiles in patients with type 2 diabetes. [RESEARCH DESIGN AND METHODS] – This was a parallel randomized controlled trial comparing three dietary advice groups each with 30\,% energy as fat: low fat, modified low fat, and modified low fat inclusive of 30 g of walnuts per day. Fifty-eight men and women, mean age 59.3 ± 8.1 years, started the trial. Dietary advice was given at baseline with monthly follow-up and fortnightly phone calls for support. Body weight, percent body fat, blood lipids, HbA1c, total antioxidant capacity, and erythrocyte fatty acid levels were measured at 0, 3, and 6 months. Data were assessed by repeated-measures ANOVA with an intention-to-treat model. [RESULTS] – The walnut group achieved a significantly greater increase in HDL cholesterol-to-total cholesterol ratio (P = 0.049) and HDL (P = 0.046) than the two other treatment groups. A 10\,% reduction in LDL cholesterol was also achieved in the walnut group, reflecting a significant effect by group (P = 0.032) and time (P = 0.036). There were no significant differences between groups for changes in body weight, percent body fat, total antioxidant capacity, or HbA1c levels. The higher dietary polyunsaturated fat-to-saturated fat ratio and intakes of ω-3 fatty acids in the walnut group were confirmed by erythrocyte biomarkers of dietary intake. [CONCLUSIONS] – Structured ” whole of diet” advice that included 30 g of walnuts/day delivering substantial amounts of polyunsaturated fatty acid improved the lipid profile of patients with type 2 diabetes.
@article{tapsellIncludingWalnutsLowfat2004,
  title = {Including Walnuts in a Low-Fat/Modified-Fat Diet Improves {{HDL}} Cholesterol-to-Total Cholesterol Ratios in Patients with Type 2 Diabetes},
  author = {Tapsell, Linda C. and Gillen, Lynda J. and Patch, Craig S. and Batterham, Marijka and Owen, Alice and Baré, Marian and Kennedy, Meredith},
  date = {2004-12},
  journaltitle = {Diabetes Care},
  volume = {27},
  pages = {2777--2783},
  issn = {1935-5548},
  doi = {10.2337/diacare.27.12.2777},
  url = {https://doi.org/10.2337/diacare.27.12.2777},
  abstract = {[OBJECTIVE] -- The aim of this study was to examine the effect of a moderate-fat diet inclusive of walnuts on blood lipid profiles in patients with type 2 diabetes. 

[RESEARCH DESIGN AND METHODS] -- This was a parallel randomized controlled trial comparing three dietary advice groups each with 30\,\% energy as fat: low fat, modified low fat, and modified low fat inclusive of 30 g of walnuts per day. Fifty-eight men and women, mean age 59.3 ± 8.1 years, started the trial. Dietary advice was given at baseline with monthly follow-up and fortnightly phone calls for support. Body weight, percent body fat, blood lipids, HbA1c, total antioxidant capacity, and erythrocyte fatty acid levels were measured at 0, 3, and 6 months. Data were assessed by repeated-measures ANOVA with an intention-to-treat model. 

[RESULTS] -- The walnut group achieved a significantly greater increase in HDL cholesterol-to-total cholesterol ratio (P = 0.049) and HDL (P = 0.046) than the two other treatment groups. A 10\,\% reduction in LDL cholesterol was also achieved in the walnut group, reflecting a significant effect by group (P = 0.032) and time (P = 0.036). There were no significant differences between groups for changes in body weight, percent body fat, total antioxidant capacity, or HbA1c levels. The higher dietary polyunsaturated fat-to-saturated fat ratio and intakes of ω-3 fatty acids in the walnut group were confirmed by erythrocyte biomarkers of dietary intake. 

[CONCLUSIONS] -- Structured ” whole of diet” advice that included 30 g of walnuts/day delivering substantial amounts of polyunsaturated fatty acid improved the lipid profile of patients with type 2 diabetes.},
  keywords = {*imported-from-citeulike-INRMM,~INRMM-MiD:c-13576824,~to-add-doi-URL,diabetes,juglans-regia},
  number = {12}
}

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