Efficient preparation of gamma-hydroxynitriles via nitrile enolate-epoxide reactions: Scope and diastereoselectivity. Taylor, S. K., DeYoung, D., Simons, L. J., Vyvyan, J. R., Wemple, M. A., & Wood, N. K. Synthetic Communications, 28(9):1691--1701, 1998. WOS:000073555900020doi abstract bibtex The nucleophilic opening of epoxides by nitrile enolates using an efficient, convenient protocol is described The diastereoselectivity of this reaction was explored and found to give syn:anti ratios ranging from 1.1:1.0 to 4.8:1.0.
@article{ taylor_efficient_1998,
title = {Efficient preparation of gamma-hydroxynitriles via nitrile enolate-epoxide reactions: Scope and diastereoselectivity},
volume = {28},
shorttitle = {Efficient preparation of gamma-hydroxynitriles via nitrile enolate-epoxide reactions},
doi = {10.1080/00397919808006873},
abstract = {The nucleophilic opening of epoxides by nitrile enolates using an efficient, convenient protocol is described The diastereoselectivity of this reaction was explored and found to give syn:anti ratios ranging from 1.1:1.0 to 4.8:1.0.},
number = {9},
journal = {Synthetic Communications},
author = {Taylor, S. K. and DeYoung, D. and Simons, L. J. and Vyvyan, J. R. and Wemple, M. A. and Wood, N. K.},
year = {1998},
note = {{WOS}:000073555900020},
pages = {1691--1701}
}
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