3.6 - Cell-based in vitro models for vaginal permeability studies. Tho, I., Škalko-Basnet, N., & Sarmento, B. In Concepts and Models for Drug Permeability Studies, pages 115–128. Woodhead Publishing, 2016. ![3.6 - Cell-based in vitro models for vaginal permeability studies [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Vaginal drug delivery is gaining increased attention as an alternative route of drug administration for both local and systemic drug action. To control drug retention at the vaginal site as well as predict drug absorption, it is highly relevant to determine the permeability of drugs and drug candidates through vaginal epithelium. This chapter aims to provide an unbiased overview of available cell-based in vitro drug permeability models. Practical approaches to selecting model type, basic handling protocols, and comments on merits and limitations are included.
@incollection{tho_3.6_2016,
title = {3.6 - {Cell}-based in vitro models for vaginal permeability studies},
isbn = {978-0-08-100094-6},
url = {http://www.sciencedirect.com/science/article/pii/B9780081000946000080},
abstract = {Vaginal drug delivery is gaining increased attention as an alternative route of drug administration for both local and systemic drug action. To control drug retention at the vaginal site as well as predict drug absorption, it is highly relevant to determine the permeability of drugs and drug candidates through vaginal epithelium. This chapter aims to provide an unbiased overview of available cell-based in vitro drug permeability models. Practical approaches to selecting model type, basic handling protocols, and comments on merits and limitations are included.},
booktitle = {Concepts and {Models} for {Drug} {Permeability} {Studies}},
publisher = {Woodhead Publishing},
author = {Tho, Ingunn and Škalko-Basnet, Nataša and Sarmento, Bruno},
year = {2016},
doi = {10.1016/B978-0-08-100094-6.00008-0},
keywords = {3D cell-based tissue model, Cervicovaginal, Drug delivery, Human explant, Immortalized cell cultures, In vitro, Permeability, Vaginal},
pages = {115--128}
}
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