Factors associated with the use of benzodiazepine and opioid prescription drug in the student population: a cross-sectional study. Thomas, C., Dondaine, T., Caron, C., Bastien, A., Chérot, N., Deheul, S., Gautier, S., Cottencin, O., Moreau-Crépeaux, S., Bordet, R., & Carton, L. Scientific reports, 14(1):13040, jun, 2024.
doi  abstract   bibtex   
The misuse of benzodiazepines and opioid medications is frequent in students. To improve our understanding of this behavior, we aimed to identify factors associated with separate and concomitant use of these substances. Anonymous self-reported questionnaires were e-mailed to students enrolled at a French university between March and July 2021, covering: sociodemographic characteristics, academics, psychoactive substance use, ADHD symptomatology (adulthood and childhood), and psychiatric/psychological or addiction follow-up. Factors associated with the use of benzodiazepines and opioid medications included female sex (OR = 1.41 [1.08; 1.86]) and OR = 1.38 [1.06; 1.79], respectively), older age (OR = 1.65 [1.04; 2.6] and OR = 2.17 [1.4; 3.36], respectively), current psychiatric/psychological follow-up (OR = 6.53 [5.18; 8.24] and OR= 1.5 [1.12; 2.0], respectively), ADHD symptomatology (OR= 2.33 [1.71;3.16] and OR= 1.61 [1.15; 2.24], respectively), polyconsumption (tobacco use for benzodiazepine users, OR = 1.38 [1.04; 1.82]; alcohol use OR = 1.67 [1.17; 2.39] and tobacco use OR = 1.62 [1.23; 2.14] for opioid users). These factors were even more strongly associated with the concomitant use of benzodiazepines and opioid medications: older age (OR = 3.64 [2.22; 5.99]), female sex (OR = 1.54 [1.1; 2.14]), grade repetition (OR = 1.7 [1.14; 2.54]), psychiatric/psychological follow-up (OR = 4.51 [3.35;6.06]), ADHD symptomatology (OR = 5.3 [3.69; 7.63]), polyconsumption (tobacco use OR = 2.05 [1.39; 3] and cannabis use, OR = 2.07 [1.97; 4.16]. The factors associated with the use of benzodiazepines and prescription opioids identified in this study could lead to the development of targeted prevention methods.
@article{Thomas2024,
abstract = {The misuse of benzodiazepines and opioid medications is frequent in students. To  improve our understanding of this behavior, we aimed to identify factors associated with separate and concomitant use of these substances. Anonymous self-reported questionnaires were e-mailed to students enrolled at a French university between March and July 2021, covering: sociodemographic characteristics, academics, psychoactive substance use, ADHD symptomatology (adulthood and childhood), and psychiatric/psychological or addiction follow-up. Factors associated with the use of benzodiazepines and opioid medications included female sex (OR = 1.41 [1.08; 1.86]) and OR = 1.38 [1.06; 1.79], respectively), older age (OR = 1.65 [1.04; 2.6] and OR = 2.17 [1.4; 3.36], respectively), current psychiatric/psychological follow-up (OR = 6.53 [5.18; 8.24] and OR= 1.5 [1.12; 2.0], respectively), ADHD symptomatology (OR= 2.33 [1.71;3.16] and OR= 1.61 [1.15; 2.24], respectively), polyconsumption (tobacco use for benzodiazepine users, OR = 1.38 [1.04; 1.82]; alcohol use OR = 1.67 [1.17; 2.39] and tobacco use OR = 1.62 [1.23; 2.14] for opioid users). These factors were even more strongly associated with the concomitant use of benzodiazepines and opioid medications: older age (OR = 3.64 [2.22; 5.99]), female sex (OR = 1.54 [1.1; 2.14]), grade repetition (OR = 1.7 [1.14; 2.54]), psychiatric/psychological follow-up (OR = 4.51 [3.35;6.06]), ADHD symptomatology (OR = 5.3 [3.69; 7.63]), polyconsumption (tobacco use OR = 2.05 [1.39; 3] and cannabis use, OR = 2.07 [1.97; 4.16]. The factors associated with the use of benzodiazepines and prescription opioids identified in this study could lead to the development of targeted prevention methods.},
author = {Thomas, Charlotte and Dondaine, Thibaut and Caron, Cl{\'{e}}ment and Bastien, Axel and Ch{\'{e}}rot, Nathalie and Deheul, Sylvie and Gautier, Sophie and Cottencin, Olivier and Moreau-Cr{\'{e}}peaux, Sophie and Bordet, R{\'{e}}gis and Carton, Louise},
doi = {10.1038/s41598-024-63037-4},
issn = {2045-2322 (Electronic)},
journal = {Scientific reports},
keywords = {Adolescent,Adult,Analgesics, Opioid,Attention Deficit Disorder with Hyperactivity,Benzodiazepines,Cross-Sectional Studies,Female,France,Humans,Male,Prescription Drug Misuse,Prescription Drugs,Students,Substance-Related Disorders,Surveys and Questionnaires,Young Adult,adverse effects,epidemiology,psychology,statistics & numerical data,therapeutic use},
language = {eng},
month = {jun},
number = {1},
pages = {13040},
pmid = {38844771},
title = {{Factors associated with the use of benzodiazepine and opioid prescription drug in  the student population: a cross-sectional study.}},
volume = {14},
year = {2024}
}

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