Pharmaceutical treatment of symptomatic vertebral fractures in primary care. Torgerson, D. J., Sykes, D., Puffer, S., Brown, P., & Cooper, C. Annals of the Rheumatic Diseases, 63(7):853--856, July, 2004. doi abstract bibtex BACKGROUND: Vertebral fractures are associated with a reduction in quality of life and are an important predictor of other non-spine fractures. Previous work has shown that up to 60% of patients with a vertebral fracture identified in primary care remain untreated. OBJECTIVE: To examine the prevalence of pharmaceutical treatment and predictors of treatment in a primary care setting. METHODS: Case-control study using the general practice research database (GPRD). All women aged 50 years and over with a first diagnosis of a vertebral fracture since 1990 were identified and matched with a control by age and practice. Appropriate use of a pharmaceutical agent was defined as a prescription occurring within 30 days of the diagnosis being recorded. RESULTS: We identified 2719 women with the same number of controls. Within 30 days of diagnosis 61% of women were prescribed treatment, compared with only 3% of the controls. Bisphosphonate was the single most important treatment prescribed. Predictors of any drug treatment included: year of fracture (most recent year increased the likelihood of treatment); age (younger patients were more likely to receive treatment); history of back pain; low body weight; history of steroid use. CONCLUSIONS: Treatment of diagnosed vertebral fractures is becoming more common. Treated patients tend to be younger but to have a higher prevalence of clinical risk factors than untreated patients. There remain significant numbers of patients who are not offered treatment.
@article{torgerson_pharmaceutical_2004,
title = {Pharmaceutical treatment of symptomatic vertebral fractures in primary care},
volume = {63},
issn = {0003-4967},
doi = {10.1136/ard.2003.013508},
abstract = {BACKGROUND: Vertebral fractures are associated with a reduction in quality of life and are an important predictor of other non-spine fractures. Previous work has shown that up to 60\% of patients with a vertebral fracture identified in primary care remain untreated.
OBJECTIVE: To examine the prevalence of pharmaceutical treatment and predictors of treatment in a primary care setting.
METHODS: Case-control study using the general practice research database (GPRD). All women aged 50 years and over with a first diagnosis of a vertebral fracture since 1990 were identified and matched with a control by age and practice. Appropriate use of a pharmaceutical agent was defined as a prescription occurring within 30 days of the diagnosis being recorded.
RESULTS: We identified 2719 women with the same number of controls. Within 30 days of diagnosis 61\% of women were prescribed treatment, compared with only 3\% of the controls. Bisphosphonate was the single most important treatment prescribed. Predictors of any drug treatment included: year of fracture (most recent year increased the likelihood of treatment); age (younger patients were more likely to receive treatment); history of back pain; low body weight; history of steroid use.
CONCLUSIONS: Treatment of diagnosed vertebral fractures is becoming more common. Treated patients tend to be younger but to have a higher prevalence of clinical risk factors than untreated patients. There remain significant numbers of patients who are not offered treatment.},
language = {eng},
number = {7},
journal = {Annals of the Rheumatic Diseases},
author = {Torgerson, D. J. and Sykes, D. and Puffer, S. and Brown, P. and Cooper, C.},
month = jul,
year = {2004},
pmid = {15194583},
pmcid = {PMC1755056},
keywords = {Age Factors, Aged, Case-Control Studies, Diphosphonates, Family Practice, Female, Glucocorticoids, Humans, Low Back Pain, Middle Aged, Patient Selection, Spinal Fractures, Time Factors},
pages = {853--856}
}
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OBJECTIVE: To examine the prevalence of pharmaceutical treatment and predictors of treatment in a primary care setting. METHODS: Case-control study using the general practice research database (GPRD). All women aged 50 years and over with a first diagnosis of a vertebral fracture since 1990 were identified and matched with a control by age and practice. Appropriate use of a pharmaceutical agent was defined as a prescription occurring within 30 days of the diagnosis being recorded. RESULTS: We identified 2719 women with the same number of controls. Within 30 days of diagnosis 61% of women were prescribed treatment, compared with only 3% of the controls. Bisphosphonate was the single most important treatment prescribed. Predictors of any drug treatment included: year of fracture (most recent year increased the likelihood of treatment); age (younger patients were more likely to receive treatment); history of back pain; low body weight; history of steroid use. CONCLUSIONS: Treatment of diagnosed vertebral fractures is becoming more common. Treated patients tend to be younger but to have a higher prevalence of clinical risk factors than untreated patients. There remain significant numbers of patients who are not offered treatment.","language":"eng","number":"7","journal":"Annals of the Rheumatic Diseases","author":[{"propositions":[],"lastnames":["Torgerson"],"firstnames":["D.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Sykes"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Puffer"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Brown"],"firstnames":["P."],"suffixes":[]},{"propositions":[],"lastnames":["Cooper"],"firstnames":["C."],"suffixes":[]}],"month":"July","year":"2004","pmid":"15194583","pmcid":"PMC1755056","keywords":"Age Factors, Aged, Case-Control Studies, Diphosphonates, Family Practice, Female, Glucocorticoids, Humans, Low Back Pain, Middle Aged, Patient Selection, Spinal Fractures, Time Factors","pages":"853--856","bibtex":"@article{torgerson_pharmaceutical_2004,\n\ttitle = {Pharmaceutical treatment of symptomatic vertebral fractures in primary care},\n\tvolume = {63},\n\tissn = {0003-4967},\n\tdoi = {10.1136/ard.2003.013508},\n\tabstract = {BACKGROUND: Vertebral fractures are associated with a reduction in quality of life and are an important predictor of other non-spine fractures. Previous work has shown that up to 60\\% of patients with a vertebral fracture identified in primary care remain untreated.\nOBJECTIVE: To examine the prevalence of pharmaceutical treatment and predictors of treatment in a primary care setting.\nMETHODS: Case-control study using the general practice research database (GPRD). All women aged 50 years and over with a first diagnosis of a vertebral fracture since 1990 were identified and matched with a control by age and practice. Appropriate use of a pharmaceutical agent was defined as a prescription occurring within 30 days of the diagnosis being recorded.\nRESULTS: We identified 2719 women with the same number of controls. Within 30 days of diagnosis 61\\% of women were prescribed treatment, compared with only 3\\% of the controls. Bisphosphonate was the single most important treatment prescribed. Predictors of any drug treatment included: year of fracture (most recent year increased the likelihood of treatment); age (younger patients were more likely to receive treatment); history of back pain; low body weight; history of steroid use.\nCONCLUSIONS: Treatment of diagnosed vertebral fractures is becoming more common. Treated patients tend to be younger but to have a higher prevalence of clinical risk factors than untreated patients. There remain significant numbers of patients who are not offered treatment.},\n\tlanguage = {eng},\n\tnumber = {7},\n\tjournal = {Annals of the Rheumatic Diseases},\n\tauthor = {Torgerson, D. 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