Heritability and demographic analyses in the large isolated population of Val Borbera suggest advantages in mapping complex traits genes. Traglia, M., Sala, C., Masciullo, C., Cverhova, V., Lori, F., Pistis, G., Bione, S., Gasparini, P., Ulivi, S., Ciullo, M., Nutile, T., Bosi, E., Sirtori, M., Mignogna, G., Rubinacci, A., Buetti, I., Camaschella, C., Petretto, E., & Toniolo, D. PloS one, 4(10):e7554, 1, 2009.
Heritability and demographic analyses in the large isolated population of Val Borbera suggest advantages in mapping complex traits genes. [pdf]Paper  Heritability and demographic analyses in the large isolated population of Val Borbera suggest advantages in mapping complex traits genes. [link]Website  abstract   bibtex   
Isolated populations are a useful resource for mapping complex traits due to shared stable environment, reduced genetic complexity and extended Linkage Disequilibrium (LD) compared to the general population. Here we describe a large genetic isolate from the North West Apennines, the mountain range that runs through Italy from the North West Alps to the South.

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