High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. Tu, L. T. P., Hoang, N. V. M., Cuong, N. V., Campbell, J., Bryant, J. E., Hoa, N. T., Kiet, B. T., Thompson, C., Duy, D. T., Phat, V. V., Hien, V. B., Thwaites, G., Baker, S., & Carrique-Mas, J. J. Epidemiology and infection, 143(14):3074–3086, October, 2015.
doi  abstract   bibtex   
We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and farm size (three categories). Pooled faeces, collected using boot swabs, were tested using ISO 6575: 2002 (Annex D). Isolates were serogrouped; group B isolates were tested by polymerase chain reaction to detect S. Typhimurium and (monophasic) serovar 4,[5],12:i:- variants. The farm-level adjusted NTS prevalence was 64.7%, 94.3% and 91.3% for chicken, duck and pig farms, respectively. Factors independently associated with NTS were duck farms [odds ratio (OR) 21.2], farm with \textgreater50 pigs (OR 11.9), pig farm with 5-50 pigs (OR 4.88) (vs. chickens), and frequent rodent sightings (OR 2.3). Both S. Typhimurium and monophasic S. Typhimurium were more common in duck farms. Isolates had a high prevalence of resistance (77.6%) against tetracycline, moderate resistance (20-30%) against chloramphenicol, sulfamethoxazole-trimethoprim, ampicillin and nalidixic acid, and low resistance (\textless5%) against ciprofloxacin and third-generation cephalosporins. Multidrug resistance (resistance against 3 classes of antimicrobial) was independently associated with monophasic S. Typhimurium and other group B isolates (excluding S. Typhimurium) and pig farms. The unusually high prevalence of NTS on Mekong Delta farms poses formidable challenges for control.
@article{tu_high_2015,
	title = {High levels of contamination and antimicrobial-resistant non-typhoidal {Salmonella} serovars on pig and poultry farms in the {Mekong} {Delta} of {Vietnam}.},
	volume = {143},
	issn = {1469-4409 0950-2688},
	doi = {10.1017/S0950268815000102},
	abstract = {We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and farm size (three categories). Pooled faeces, collected using boot swabs, were tested using  ISO 6575: 2002 (Annex D). Isolates were serogrouped; group B isolates were tested by polymerase chain reaction to detect S. Typhimurium and (monophasic) serovar 4,[5],12:i:- variants. The farm-level adjusted NTS prevalence was 64.7\%, 94.3\% and 91.3\% for chicken, duck and pig farms, respectively. Factors independently associated with NTS were duck farms [odds ratio (OR) 21.2], farm with {\textgreater}50 pigs (OR 11.9), pig farm with 5-50 pigs (OR 4.88) (vs. chickens), and frequent rodent  sightings (OR 2.3). Both S. Typhimurium and monophasic S. Typhimurium were more common in duck farms. Isolates had a high prevalence of resistance (77.6\%) against tetracycline, moderate resistance (20-30\%) against chloramphenicol, sulfamethoxazole-trimethoprim, ampicillin and nalidixic acid, and low resistance  ({\textless}5\%) against ciprofloxacin and third-generation cephalosporins. Multidrug resistance (resistance against 3 classes of antimicrobial) was independently associated with monophasic S. Typhimurium and other group B isolates (excluding S. Typhimurium) and pig farms. The unusually high prevalence of NTS on Mekong Delta farms poses formidable challenges for control.},
	language = {eng},
	number = {14},
	journal = {Epidemiology and infection},
	author = {Tu, L. T. P. and Hoang, N. V. M. and Cuong, N. V. and Campbell, J. and Bryant, J. E. and Hoa, N. T. and Kiet, B. T. and Thompson, C. and Duy, D. T. and Phat, V. V. and Hien, V. B. and Thwaites, G. and Baker, S. and Carrique-Mas, J. J.},
	month = oct,
	year = {2015},
	pmid = {25778282},
	pmcid = {PMC4595858},
	keywords = {*Animal Husbandry, *Drug Resistance, Bacterial, *Environmental Pollution, *Poultry, *Swine, Animals, Epidemiology, Feces/microbiology, Prevalence, Salmonella, Salmonella Infections, Animal/*epidemiology/microbiology, Salmonella/drug effects/*isolation \& purification, Serotyping, Vietnam, zoonoses},
	pages = {3074--3086},
}

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