Brain networks of spatial awareness: Evidence from diffusion tensor imaging tractography. Urbanski, M., Thiebaut de Schotten, M., Rodrigo, S., Catani, M., Oppenheim, C., Touze, E., Chokron, S., Meder, J., Levy, R., Dubois, B., & Bartolomeo, P. J Neurol Neurosurg Psychiatry, November, 2007. abstract bibtex Left unilateral neglect, a dramatic condition which impairs awareness of left-sided events, has been classically reported after right hemisphere cortical lesions involving the inferior parietal region. More recently, the involvement of long-range white matter tracts has been highlighted, consistent with the idea that awareness of events occurring in space depends on the coordinated activity of anatomically distributed brain regions. Damage to the superior longitudinal fasciculus (SLF), linking parietal to frontal cortical regions, or to the inferior longitudinal fasciculus (ILF), connecting occipital and temporal lobes, have been described in neglect patients. In this study four right-handed patients with right-hemisphere strokes were submitted to a high-definition anatomical MRI with diffusion tensor imaging (DTI) sequences and to a paper-and-pencil neglect battery. We used DTI tractography to visualize the SLF, the ILF and the inferior fronto-occipital fasciculus (IFOF), a pathway running in the depth of the temporal lobe, not hitherto associated with neglect. Two patients with cortical involvement of the inferior parietal and superior temporal regions, but intact and symmetrical fasciculi, showed no signs of neglect. The other two patients with signs of left neglect had superficial damage to the inferior parietal cortex and white matter damage involving the IFOF. These findings suggest that superficial damage to the inferior parietal cortex per se may not be sufficient to produce visual neglect. In some cases, a lesion to the direct connections between ventral occipital and frontal regions (i.e. IFOF) may contribute to the manifestation of neglect by impairing the top-down modulation of visual areas from frontal cortex.
@article{urbanski_brain_2007,
title = {Brain networks of spatial awareness: {Evidence} from diffusion tensor imaging tractography},
issn = {1468330},
abstract = {Left unilateral neglect, a dramatic condition which impairs awareness of left-sided events, has been classically reported after right hemisphere cortical lesions involving the inferior parietal region. More recently, the involvement of long-range white matter tracts has been highlighted, consistent with the idea that awareness of events occurring in space depends on the coordinated activity of anatomically distributed brain regions. Damage to the superior longitudinal fasciculus (SLF), linking parietal to frontal cortical regions, or to the inferior longitudinal fasciculus (ILF), connecting occipital and temporal lobes, have been described in neglect patients. In this study four right-handed patients with right-hemisphere strokes were submitted to a high-definition anatomical MRI with diffusion tensor imaging (DTI) sequences and to a paper-and-pencil neglect battery. We used DTI tractography to visualize the SLF, the ILF and the inferior fronto-occipital fasciculus (IFOF), a pathway running in the depth of the temporal lobe, not hitherto associated with neglect. Two patients with cortical involvement of the inferior parietal and superior temporal regions, but intact and symmetrical fasciculi, showed no signs of neglect. The other two patients with signs of left neglect had superficial damage to the inferior parietal cortex and white matter damage involving the IFOF. These findings suggest that superficial damage to the inferior parietal cortex per se may not be sufficient to produce visual neglect. In some cases, a lesion to the direct connections between ventral occipital and frontal regions (i.e. IFOF) may contribute to the manifestation of neglect by impairing the top-down modulation of visual areas from frontal cortex.},
journal = {J Neurol Neurosurg Psychiatry},
author = {Urbanski, Marika and Thiebaut de Schotten, Michel and Rodrigo, Sebastian and Catani, Marco and Oppenheim, Catherine and Touze, Emmanuel and Chokron, Sylvie and Meder, Jean-Francois and Levy, Richard and Dubois, Bruno and Bartolomeo, Paolo},
month = nov,
year = {2007},
keywords = {\#nosource, Aged, 80 and over, Awareness, Cerebral Cortex, Diffusion Magnetic Resonance Imaging, Dominance, Cerebral, Female, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Kinesthesis, Male, Middle Aged, Nerve Fibers, Myelinated, Nerve Net, Perceptual Disorders, Stroke, Unilateral Neglect, Spatial Attention, Diffusion MRI, awareness, ⛔ No DOI found},
}
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{"_id":"7e9gL8WKSRTh9JiWA","bibbaseid":"urbanski-thiebautdeschotten-rodrigo-catani-oppenheim-touze-chokron-meder-etal-brainnetworksofspatialawarenessevidencefromdiffusiontensorimagingtractography-2007","author_short":["Urbanski, M.","Thiebaut de Schotten, M.","Rodrigo, S.","Catani, M.","Oppenheim, C.","Touze, E.","Chokron, S.","Meder, J.","Levy, R.","Dubois, B.","Bartolomeo, P."],"bibdata":{"bibtype":"article","type":"article","title":"Brain networks of spatial awareness: Evidence from diffusion tensor imaging tractography","issn":"1468330","abstract":"Left unilateral neglect, a dramatic condition which impairs awareness of left-sided events, has been classically reported after right hemisphere cortical lesions involving the inferior parietal region. More recently, the involvement of long-range white matter tracts has been highlighted, consistent with the idea that awareness of events occurring in space depends on the coordinated activity of anatomically distributed brain regions. Damage to the superior longitudinal fasciculus (SLF), linking parietal to frontal cortical regions, or to the inferior longitudinal fasciculus (ILF), connecting occipital and temporal lobes, have been described in neglect patients. In this study four right-handed patients with right-hemisphere strokes were submitted to a high-definition anatomical MRI with diffusion tensor imaging (DTI) sequences and to a paper-and-pencil neglect battery. We used DTI tractography to visualize the SLF, the ILF and the inferior fronto-occipital fasciculus (IFOF), a pathway running in the depth of the temporal lobe, not hitherto associated with neglect. Two patients with cortical involvement of the inferior parietal and superior temporal regions, but intact and symmetrical fasciculi, showed no signs of neglect. The other two patients with signs of left neglect had superficial damage to the inferior parietal cortex and white matter damage involving the IFOF. These findings suggest that superficial damage to the inferior parietal cortex per se may not be sufficient to produce visual neglect. In some cases, a lesion to the direct connections between ventral occipital and frontal regions (i.e. IFOF) may contribute to the manifestation of neglect by impairing the top-down modulation of visual areas from frontal cortex.","journal":"J Neurol Neurosurg Psychiatry","author":[{"propositions":[],"lastnames":["Urbanski"],"firstnames":["Marika"],"suffixes":[]},{"propositions":["Thiebaut","de"],"lastnames":["Schotten"],"firstnames":["Michel"],"suffixes":[]},{"propositions":[],"lastnames":["Rodrigo"],"firstnames":["Sebastian"],"suffixes":[]},{"propositions":[],"lastnames":["Catani"],"firstnames":["Marco"],"suffixes":[]},{"propositions":[],"lastnames":["Oppenheim"],"firstnames":["Catherine"],"suffixes":[]},{"propositions":[],"lastnames":["Touze"],"firstnames":["Emmanuel"],"suffixes":[]},{"propositions":[],"lastnames":["Chokron"],"firstnames":["Sylvie"],"suffixes":[]},{"propositions":[],"lastnames":["Meder"],"firstnames":["Jean-Francois"],"suffixes":[]},{"propositions":[],"lastnames":["Levy"],"firstnames":["Richard"],"suffixes":[]},{"propositions":[],"lastnames":["Dubois"],"firstnames":["Bruno"],"suffixes":[]},{"propositions":[],"lastnames":["Bartolomeo"],"firstnames":["Paolo"],"suffixes":[]}],"month":"November","year":"2007","keywords":"#nosource, Aged, 80 and over, Awareness, Cerebral Cortex, Diffusion Magnetic Resonance Imaging, Dominance, Cerebral, Female, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Kinesthesis, Male, Middle Aged, Nerve Fibers, Myelinated, Nerve Net, Perceptual Disorders, Stroke, Unilateral Neglect, Spatial Attention, Diffusion MRI, awareness, ⛔ No DOI found","bibtex":"@article{urbanski_brain_2007,\n\ttitle = {Brain networks of spatial awareness: {Evidence} from diffusion tensor imaging tractography},\n\tissn = {1468330},\n\tabstract = {Left unilateral neglect, a dramatic condition which impairs awareness of left-sided events, has been classically reported after right hemisphere cortical lesions involving the inferior parietal region. More recently, the involvement of long-range white matter tracts has been highlighted, consistent with the idea that awareness of events occurring in space depends on the coordinated activity of anatomically distributed brain regions. Damage to the superior longitudinal fasciculus (SLF), linking parietal to frontal cortical regions, or to the inferior longitudinal fasciculus (ILF), connecting occipital and temporal lobes, have been described in neglect patients. In this study four right-handed patients with right-hemisphere strokes were submitted to a high-definition anatomical MRI with diffusion tensor imaging (DTI) sequences and to a paper-and-pencil neglect battery. We used DTI tractography to visualize the SLF, the ILF and the inferior fronto-occipital fasciculus (IFOF), a pathway running in the depth of the temporal lobe, not hitherto associated with neglect. Two patients with cortical involvement of the inferior parietal and superior temporal regions, but intact and symmetrical fasciculi, showed no signs of neglect. The other two patients with signs of left neglect had superficial damage to the inferior parietal cortex and white matter damage involving the IFOF. These findings suggest that superficial damage to the inferior parietal cortex per se may not be sufficient to produce visual neglect. In some cases, a lesion to the direct connections between ventral occipital and frontal regions (i.e. IFOF) may contribute to the manifestation of neglect by impairing the top-down modulation of visual areas from frontal cortex.},\n\tjournal = {J Neurol Neurosurg Psychiatry},\n\tauthor = {Urbanski, Marika and Thiebaut de Schotten, Michel and Rodrigo, Sebastian and Catani, Marco and Oppenheim, Catherine and Touze, Emmanuel and Chokron, Sylvie and Meder, Jean-Francois and Levy, Richard and Dubois, Bruno and Bartolomeo, Paolo},\n\tmonth = nov,\n\tyear = {2007},\n\tkeywords = {\\#nosource, Aged, 80 and over, Awareness, Cerebral Cortex, Diffusion Magnetic Resonance Imaging, Dominance, Cerebral, Female, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Kinesthesis, Male, Middle Aged, Nerve Fibers, Myelinated, Nerve Net, Perceptual Disorders, Stroke, Unilateral Neglect, Spatial Attention, Diffusion MRI, awareness, ⛔ No DOI found},\n}\n\n","author_short":["Urbanski, M.","Thiebaut de Schotten, M.","Rodrigo, S.","Catani, M.","Oppenheim, C.","Touze, E.","Chokron, S.","Meder, J.","Levy, R.","Dubois, B.","Bartolomeo, P."],"key":"urbanski_brain_2007","id":"urbanski_brain_2007","bibbaseid":"urbanski-thiebautdeschotten-rodrigo-catani-oppenheim-touze-chokron-meder-etal-brainnetworksofspatialawarenessevidencefromdiffusiontensorimagingtractography-2007","role":"author","urls":{},"keyword":["#nosource","Aged","80 and over","Awareness","Cerebral Cortex","Diffusion Magnetic Resonance Imaging","Dominance","Cerebral","Female","Humans","Image Processing","Computer-Assisted","Imaging","Three-Dimensional","Kinesthesis","Male","Middle Aged","Nerve Fibers","Myelinated","Nerve Net","Perceptual Disorders","Stroke","Unilateral Neglect","Spatial Attention","Diffusion MRI","awareness","⛔ No DOI found"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://api.zotero.org/users/10176/collections/TF8X26N8/items?key=7qraobRCjdfVup9q5USnsAPd&format=bibtex&limit=100","dataSources":["FiAwa3WyFa4YNpBnH","MDN92uztrK9rBiHJj","ETrv3dJ8d99xS3hnM","uAjmjGrDPcqisdqtM","HxyCDbhEsgZuppBr5","5GYP3zzf4H9cjs52t"],"keywords":["#nosource","aged","80 and over","awareness","cerebral cortex","diffusion magnetic resonance imaging","dominance","cerebral","female","humans","image processing","computer-assisted","imaging","three-dimensional","kinesthesis","male","middle aged","nerve fibers","myelinated","nerve net","perceptual disorders","stroke","unilateral neglect","spatial attention","diffusion mri","awareness","⛔ no doi found"],"search_terms":["brain","networks","spatial","awareness","evidence","diffusion","tensor","imaging","tractography","urbanski","thiebaut de schotten","rodrigo","catani","oppenheim","touze","chokron","meder","levy","dubois","bartolomeo"],"title":"Brain networks of spatial awareness: Evidence from diffusion tensor imaging tractography","year":2007}