@article{ Usrey_etal00,
  author = {Usrey, W. M. and Alonso, J. M. and Reid, R. C.},
  title = {Synaptic interactions between thalamic inputs to simple cells in
	cat visual cortex},
  journal = {J. Neurosci.},
  year = {2000},
  volume = {20},
  pages = {5461-7},
  number = {14},
  month = {Jul},
  abstract = {Laboratory of Neurobiology, The Rockefeller University, New York,
	New York 10021, USA. We performed experiments in the cat geniculocortical
	pathway, in vivo, to examine how presynaptic spikes interact to influence
	the firing of postsynaptic targets. In particular, we asked (1) how
	do multiple spikes from a single presynaptic neuron interact to influence
	the firing of a postsynaptic target (homosynaptic interactions),
	(2) how do spikes from two different presynaptic neurons interact
	(heterosynaptic interactions), and (3) what is the time course of
	homosynaptic and heterosynaptic interactions? We found that both
	homosynaptic and heterosynaptic interactions increase the likelihood
	of driving a postsynaptic spike, although with different time courses.
	For two spikes traveling down a single geniculate axon, the second
	spike is more effective than the first for approximately 15 msec.
	For two spikes on separate axons, the interaction is faster ( approximately
	7 msec duration, approximately 2.5 msec time constant). Thus changes
	in firing rate are perhaps best relayed by homosynaptic interactions,
	whereas heterosynaptic interactions may help detect coincident spikes
	from different thalamic inputs}
}

{"_id":"pBSGpaPZxkXhMqdgx","bibbaseid":"usrey-alonso-reid-synapticinteractionsbetweenthalamicinputstosimplecellsincatvisualcortex-2000","downloads":0,"creationDate":"2015-02-08T05:14:59.983Z","title":"Synaptic interactions between thalamic inputs to simple cells in cat visual cortex","author_short":["Usrey, W.<nbsp>M.","Alonso, J.<nbsp>M.","Reid, R.<nbsp>C."],"year":2000,"bibtype":"article","biburl":"http://cnslab.mb.jhu.edu/niebase.bib","bibdata":{"abstract":"Laboratory of Neurobiology, The Rockefeller University, New York, New York 10021, USA. We performed experiments in the cat geniculocortical pathway, in vivo, to examine how presynaptic spikes interact to influence the firing of postsynaptic targets. In particular, we asked (1) how do multiple spikes from a single presynaptic neuron interact to influence the firing of a postsynaptic target (homosynaptic interactions), (2) how do spikes from two different presynaptic neurons interact (heterosynaptic interactions), and (3) what is the time course of homosynaptic and heterosynaptic interactions? We found that both homosynaptic and heterosynaptic interactions increase the likelihood of driving a postsynaptic spike, although with different time courses. For two spikes traveling down a single geniculate axon, the second spike is more effective than the first for approximately 15 msec. For two spikes on separate axons, the interaction is faster ( approximately 7 msec duration, approximately 2.5 msec time constant). Thus changes in firing rate are perhaps best relayed by homosynaptic interactions, whereas heterosynaptic interactions may help detect coincident spikes from different thalamic inputs","author":["Usrey, W. M.","Alonso, J. M.","Reid, R. C."],"author_short":["Usrey, W.<nbsp>M.","Alonso, J.<nbsp>M.","Reid, R.<nbsp>C."],"bibtex":"@article{ Usrey_etal00,\n author = {Usrey, W. M. and Alonso, J. M. and Reid, R. C.},\n title = {Synaptic interactions between thalamic inputs to simple cells in\n\tcat visual cortex},\n journal = {J. Neurosci.},\n year = {2000},\n volume = {20},\n pages = {5461-7},\n number = {14},\n month = {Jul},\n abstract = {Laboratory of Neurobiology, The Rockefeller University, New York,\n\tNew York 10021, USA. We performed experiments in the cat geniculocortical\n\tpathway, in vivo, to examine how presynaptic spikes interact to influence\n\tthe firing of postsynaptic targets. In particular, we asked (1) how\n\tdo multiple spikes from a single presynaptic neuron interact to influence\n\tthe firing of a postsynaptic target (homosynaptic interactions),\n\t(2) how do spikes from two different presynaptic neurons interact\n\t(heterosynaptic interactions), and (3) what is the time course of\n\thomosynaptic and heterosynaptic interactions? We found that both\n\thomosynaptic and heterosynaptic interactions increase the likelihood\n\tof driving a postsynaptic spike, although with different time courses.\n\tFor two spikes traveling down a single geniculate axon, the second\n\tspike is more effective than the first for approximately 15 msec.\n\tFor two spikes on separate axons, the interaction is faster ( approximately\n\t7 msec duration, approximately 2.5 msec time constant). Thus changes\n\tin firing rate are perhaps best relayed by homosynaptic interactions,\n\twhereas heterosynaptic interactions may help detect coincident spikes\n\tfrom different thalamic inputs}\n}","bibtype":"article","id":"Usrey_etal00","journal":"J. Neurosci.","key":"Usrey_etal00","month":"Jul","number":"14","pages":"5461-7","title":"Synaptic interactions between thalamic inputs to simple cells in cat visual cortex","type":"article","volume":"20","year":"2000","bibbaseid":"usrey-alonso-reid-synapticinteractionsbetweenthalamicinputstosimplecellsincatvisualcortex-2000","role":"author","urls":{},"downloads":0},"search_terms":["synaptic","interactions","between","thalamic","inputs","simple","cells","cat","visual","cortex","usrey","alonso","reid"],"keywords":[],"authorIDs":[],"dataSources":["ErLXoH8mqSjESnrN5"]}